A5102954611- Historical Studies and Socio-cultural Analysis
- European Political History Analysis
- Multiculturalism, Politics, Migration, Gender
- Political and Social Issues
- French Historical and Cultural Studies
- Radio Frequency Integrated Circuit Design
- Religious Tourism and Spaces
- French Urban and Social Studies
- Diverse Cultural and Historical Studies
- Religion and Society Interactions
- Theology and Canon Law Studies
- Diet and metabolism studies
- CAR-T cell therapy research
- Cultural Identity and Heritage
- Immune Cell Function and Interaction
- Advanced Power Amplifier Design
- Metabolism and Genetic Disorders
- Metabolism, Diabetes, and Cancer
- Advancements in PLL and VCO Technologies
- GaN-based semiconductor devices and materials
- Cancer Research and Treatments
- Digital Imaging for Blood Diseases
- Analog and Mixed-Signal Circuit Design
- Education, sociology, and vocational training
- Historical and Literary Studies
Schneider Electric (Germany)
2020-2025
University of Mauritius
2023
Thales (France)
2004-2023
Commissariat à l'Énergie Atomique et aux Énergies Alternatives
2023
Centre National de la Recherche Scientifique
2007-2023
Sorbonne Université
2023
CEA Paris-Saclay
2023
Inserm
2023
Centre d'Etudes Supérieures de la Renaissance
2023
Université de Montpellier
2023
Nonalcoholic fatty liver disease (NAFLD) is commonly associated with obesity, metabolic syndrome, and type 2 diabetes. Several studies suggest that NAFLD independently an increased risk of cardiovascular in nondiabetic subjects. In diabetic subjects, the link between atherosclerosis less clear. this study, we set out to determine, whether content, evaluated using 1H-magnetic resonance spectroscopy, a very precise imaging technique, was people diabetes.A total 101 patients diabetes mellitus...
Diabetes affects roughly 537 million people in the world, and it is predicted to reach 783 by 2045. Diabetic Foot Ulcer (DFU) a major issue with diabetes that may lead lower limb amputation. The rapid evolution of DFU demands immediate intervention prevent terrible consequences amputation related complications.This research introduces novel approach utilizing deep neural networks machine learning for accurate classification diabetic foot ulcer images. proposed method harnesses cutting-edge...
Dengue is caused by a taxonomic group of four viruses, dengue virus types 1-4 (DENV1-DENV4). A molecular understanding the antibody-mediated protection against this disease critical to design safe vaccines and therapeutics. Here, energetic epitope antibody mAb4E11, which neutralizes serotypes DENV but no other flavivirus, binds domain 3 (ED3) their envelope glycoprotein, was characterized. Alanine-scanning mutagenesis ED3 from serotype DENV1 performed affinities between mutant domains Fab...
Glucose transporter type 1 (GLUT1) deficiency syndrome (GLUT1-DS) leads to a wide range of neurological symptoms. Ketogenic diets are very efficient control epilepsy and movement disorders. We tested novel simple rapid blood test in 30 patients with GLUT1-DS predominant disorders, 18 disorders attributed other genetic defects, 346 healthy controls. detected significantly reduced GLUT1 expression only on red cells from (23 patients; 78%), including inconclusive analysis. This opens...
<title>Abstract</title> Building decarbonization is critical for meeting long-term climate goals, given the embodied energy, material and resource flows involved in making buildings, operational energy use, need to both build new facilities meet growing populations retrofit older, less efficient homes businesses. In this review, authors examine ninety-five sociotechnical barriers that inhibit progress on of building sector can be categorized by economic, political, social, behavioral,...
Objective GLUT1 deficiency syndrome (Glut1DS) is a treatable neurometabolic disease that causes wide range of neurological symptoms in children and adults. However, its diagnosis relies on an invasive test, i.e., lumbar puncture (LP) to measure glycorrhachia, and, sometimes complex, molecular analyses the <i>SLC2A1</i> gene. This procedure limits number patients able receive standard care. We wished validate diagnostic performance METAglut1™, simple blood test quantifies at erythrocyte...
Statin treatment of hypercholesterolemia can lead to chronic myotoxicity which is, in most cases, alleviated by drug withdrawal. Cellular and molecular mechanisms this adverse effect have been elusive, particular because the lack vitro models suitable for long-term exposures. We taken advantage properties human pluripotent stem cell-derived mesodermal precursors, that be maintained unaltered a long period time, develop model repeated exposures simvastatin during more than 2 weeks. This...
Abstract Objective The goal of this study is to demonstrate the utility a growth assay quantify functional impact single nucleotide variants (SNVs) in SLC2A1 , gene responsible for Glut1DS. Methods 40 SNVs was quantitatively determined HAP1 cells which required growth. Donor libraries were introduced into endogenous HAP1‐Lig4KO using CRISPR/Cas9. Cell populations harvested and sequenced effect on generate score. Quantitative scores compared 3‐OMG uptake, cell surface expression, CADD score,...
This paper presents a highly compact Ku band 130nm SiGe power amplifier (PA) in double balanced architecture. A low-loss 4 to 1 combiner is associated with cascode topology provide combination up 1W and high resilience the standing wave ratio (SWR) from 2:1 4:1. thermal stability 120°C ensured by an advanced configuration of transistors. choices innovative set on stage design layout improves control impact ionization selfheating. driver allows circuit achieve over 20 dB linear gain. At 30°C,...
In response to a number of growing global health challenges, New York University and UNICEF designed Behavioral Communication Strategies for Global Epidemics course that brings together United Nations professionals, government staff, MPH (Master Public Health) students design innovative social behavior change communication (SBCC) strategies address disease outbreaks humanitarian challenges around the world. Applying systems approach, participants in work on interdisciplinary teams...
Diabetes affects roughly 537 million people, and is predicted to reach 783 by 2045. Foot Ulcer (DFU) a major complication associated with diabetes can lead lower limb amputation. The rapid evolution of diabetic foot ulcers (DFUs) necessitates immediate intervention prevent the severe consequences amputation related complications. Continuous meticulous patient monitoring for individuals crucial currently carried out medical practitioners on daily basis. This research article introduces...
170 Background: CRC is the 4 th leading cause of global cancer-related deaths, and novel therapeutic strategies for advanced are urgently needed. Adoptive cell therapy (ACT) effective in treating hematological malignancies; however, ACT solid tumors hindered by target antigen identification, restricted migration into tumors, survival tumor microenvironment (TME) due to immunosuppressive signals scarcity nutrients. NK cells central anti-tumor immunity can directly eliminate without prior...
It is a known fact that AI models need massive amounts of data for training. In the medical field, are not necessarily available at single site but distributed over several sites. field sharing, particularly among healthcare institutions, to maintain confidentiality sensitive information often restricts comprehensive utilization real-world in machine learning. To address this challenge, our study experiments with an innovative approach using federated learning enable collaborative model...
We applied a novel profiling approach using receptor binding domain (RBD) ligands to cell surface domains of panel nutrient transporters characterize the impact number tyrosine kinase inhibitor anticancer drugs on human stem cell-derived cardiomyocytes. High-content screening and flow cytometry analysis showed diagnostic changes in transporter expression correlating with glycolysis oxidative phosphorylation-based metabolism glucose galactose media. Cluster RBD signatures drug-treated cells...
This paper presents a compact quasi inverse class-F highly efficient power amplifier (PA) based on the 130 nm SiGe technology. The purpose is to drive high output with added efficiency (PAE) over X-band, while ensuring good amplitude and phase linearity. To do that, differential cascode topology low base impedance has been used. Measured results exhibit 51.8% peak PAE 25.7 dBm at 9 GHz. our knowledge, this PA demonstrates highest linear behaviour among Si-based X-band amplifiers found in literature.
L’invention de saint Napoléon en 1806 relève la raison d’État : il s’agit d’un acte hautement politique, sanctionné explicitement après coup par un dignitaire l’Église catholique puis implicitement, mûr examen, Curie. L’initiative Portalis et du cardinal Caprara, qui consiste d’une part office liturgique célébré le clergé les fidèles, d’autre une fête publique destinée à associer l’ensemble des citoyens, fait l’objet Rome réflexion fois historique politique apparaît décisive dans l’évolution...
A step-by-step simulation methodology for large-bandwidth Track-and-hold (T/H) microwave circuit is proposed. T/H characterized accurately under the Cadence <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">©</sup> environment. With consideration of a specific windowing function, linearity analysis could be done effectively. Moreover, use an input frequency generation in accordance with theoretical calculation, allows to treat entire bandwidth...
In his famous work The Civilisation of Manners, Norbert Elias regarded the church purely as an agent in process implanting practices court among lower social groups. Entirely enveloped state and possessing a quasi-monopoly on teaching, preaching publishing, was seen by him effective intermediary civilising manners, which it only required to christianise. But what if, instead simply appropriating then propagating model that not its own making, did not, contrary, continue from 16th century...
La Paroisse universitaire qui réunit les enseignants catholiques de l’enseignement public a joué un rôle important dans le diocèse Besançon, terre chrétienté fervente mais républicaine et patriote. Ses membres ont été à la pointe l’aggiornamento du monde catholique partir 1945, que ce soit avec l’acceptation définitive principe laïcité l’école, ralliement des partis gauche, sur terrain spécifiquement religieux, liturgie l’œcuménisme. Cette étude, au plus près terrain, s’attachera surtout...