Yan He

ORCID: 0009-0003-2947-2642
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About
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Research Areas
  • Congenital Heart Disease Studies
  • Pancreatitis Pathology and Treatment
  • Dialysis and Renal Disease Management
  • Pregnancy and preeclampsia studies
  • Acute Kidney Injury Research
  • Soft tissue tumor case studies
  • Neuroinflammation and Neurodegeneration Mechanisms
  • MicroRNA in disease regulation
  • Cancer Mechanisms and Therapy
  • Colorectal Cancer Treatments and Studies
  • Congenital heart defects research
  • Reproductive tract infections research
  • Inflammatory Biomarkers in Disease Prognosis
  • Circular RNAs in diseases
  • Urinary Tract Infections Management
  • Gut microbiota and health
  • RNA Research and Splicing
  • Pituitary Gland Disorders and Treatments
  • Ectopic Pregnancy Diagnosis and Management
  • Metabolism, Diabetes, and Cancer
  • Abdominal Surgery and Complications
  • Sarcoma Diagnosis and Treatment
  • Congenital Anomalies and Fetal Surgery
  • Antibiotic Use and Resistance
  • Pharmacy and Medical Practices

Sichuan University
2024-2025

West China Hospital of Sichuan University
2025

University of Chinese Academy of Sciences
2021-2025

Wuhan University of Science and Technology
2025

Shanghai Institute of Technical Physics
2025

Second Affiliated Hospital of Jilin University
2025

Peking University Shenzhen Hospital
2008-2024

Longgang Central Hospital
2020-2024

Zhujiang Hospital
2023-2024

Southern Medical University
2021-2024

Photonic integrated interferometric imaging systems (PIISs) provide a compact solution for high-resolution Earth observation missions with stringent size, weight, and power (SWaP) constraints. As an indirect method, PIIS exhibits fundamentally different noise response characteristics compared to conventional remote sensing systems, its performance under practical operational scenarios has not been thoroughly investigated. The primary objective of this paper is evaluate the capabilities PIISs...

10.3390/rs17091484 article EN cc-by Remote Sensing 2025-04-22

Cisplatin resistance significantly impedes effective treatment of non-small cell lung cancer (NSCLC). This study investigates the role M6A-related circFUT8/miR-185-5p/HNRNPC competing endogenous RNA (ceRNA) axis in NSCLC cisplatin resistance. Bioinformatics analysis identified HNRNPC, a critical M6A modification-related gene, as promoter proliferation and metastasis. Our vitro vivo experiments reveal that circFUT8 upregulates HNRNPC by sponging miR-185-5p, thus enhancing proliferation,...

10.1152/ajpcell.00881.2024 article EN AJP Cell Physiology 2025-04-28

Background There is no effective drug treatment for the organ failure (OF) caused by severe acute pancreatitis (SAP). Objective We aimed to evaluate efficacy of cyclooxygenase-2 inhibitors (COX-2-Is) on SAP and its safety. Design In this multicentre, double-blind, randomised, placebo-controlled, investigator-initiated trial, 348 patients with aged 18–75 years, <1 week from onset illness admission, Acute Physiology Chronic Health Evaluation II Score ≥7 or modified Marshall ≥2, were...

10.1136/gutjnl-2024-334038 article EN Gut 2025-04-29

Objective To enhance the understanding of splenectomy in children with hereditary spherocytosis, specifically focusing on preservation accessory spleens or partial splenectomy. Methods A retrospective review clinical data and surgical methods a child spherocytosis who underwent surgery for spleen hyperfunction 7 years after at General Surgery Department Anhui Provincial Children's Hospital, along literature review. Results The successfully single-port plus one laparoscopic spleenectomy....

10.3389/fped.2025.1572397 article EN cc-by Frontiers in Pediatrics 2025-05-26

Purpose: Antibiotic administration leads to alterations in pathogenic organisms and antibiotic resistance, posing a significant risk peritoneal dialysis patients' health.This study aimed investigate changes the cause-specific peritonitis, pathogen profiles, prognostic factors among patients with dialysis-associated peritonitis (PDAP) at our center.Patients Methods: We included 463 PDAP who attended Peking University Shenzhen Hospital between 2002 2023.We analyzed effects of empirical...

10.2147/idr.s442641 article EN cc-by-nc Infection and Drug Resistance 2024-02-01

ABSTRACT Colorectal cancer (CRC) is the most common gastrointestinal malignancy, with its recurrence and metastasis significantly affecting patient survival. Circular RNAs (circRNAs), a novel class of noncoding RNAs, have emerged as crucial contributors to CRC pathogenesis. However, role circEIF3I in remains unclear. Quantitative real‐time polymerase chain reaction (qRT‐PCR) was applied assess circEIF3I, microRNA (miR)‐328‐3p, NCAPH expression. cell migration invasion were determined via...

10.1002/mc.23860 article EN Molecular Carcinogenesis 2024-12-02

Peripheral blood lymphocyte counts is a pivotal parameter in assessing the host's immune response during maladies and equilibrium of system which has been found to correlate with various diseases progression prognosis. However, there was no study on patients peritoneal dialysis-associated peritonitis (PDAP). We sought investigate prognostic value baseline peripheral count PDAP patients.This retrospective analyzed data from 286 over nine years. Episodes were categorized according tertiles...

10.2147/jir.s438674 article EN cc-by-nc Journal of Inflammation Research 2023-11-01

Melanoma is considered as the most frequent primary malignancy occurring in skin. Accumulating studies have suggested that long non-coding RNAs (lncRNAs) play critical parts multiple cancers. In this study, we explored molecular mechanism of ZBED3 antisense RNA 1 (ZBED3-AS1) melanoma. We observed ZBED3-AS1 expression was remarkably up-regulated melanoma tissues, and high level linked to unsatisfactory survival patients. Then, discovered overexpressed cells compared with human epidermal...

10.1080/15476286.2021.1950463 article EN RNA Biology 2021-07-09

Background and Objectives: Peritoneal dialysis-associated peritonitis (PDAP) poses significant challenges in peritoneal dialysis (PD) patient management outcomes. Total bilirubin has gained attention due to its antioxidant immunomodulatory properties. However, relationship with PDAP prognosis remains underexplored. Materials Methods: We conducted a retrospective single-center study involving 243 patients stratified into tertile-based groups according total levels. The association between...

10.3390/medicina59101837 article EN cc-by Medicina 2023-10-16

This study aims to investigate the potential correlation between baseline red cell distribution width (RDW) albumin ratio (RAR) levels and treatment failure in peritoneal dialysis-associated peritonitis (PDAP) patients.

10.1111/1744-9987.14098 article EN Therapeutic Apheresis and Dialysis 2023-12-19

Although several studies have identified a distinct gut microbiota in individuals with acute ischemic stroke (AIS), there is limited amount of research that has simultaneously investigated alterations the oral and intestinal AIS patients their correlation clinical prognosis. This was prospective observational single-center cohort study which we included 160 who were admitted within 24 h after event. We collected rectal swab samples for analysis using 16S rRNA high-throughput sequencing. Our...

10.1007/s12035-024-04618-2 article EN cc-by-nc-nd Molecular Neurobiology 2024-11-15

Abstract Introduction Reconstruction of composite oromandibular defects oral malignancy is a challenging problem for oromaxillofacial and plastic surgeons. Revolutionary microvascular surgical techniques permit surgeons to use two free flaps in one stage— the bone inner lining skin or soft tissue. But some cases with poor quality recipient vessel site heavily irradiated neck condition, these also have problems, especially ablative large soft-tissue loss. The aim this article was report case...

10.13172/2052-7837-1-3-746 article EN cc-by Annals of Oral and Maxillofacial Surgery 2013-08-01

10.1002/uog.19377 article EN Ultrasound in Obstetrics and Gynecology 2018-10-01
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