A5100553414- Xenotransplantation and immune response
- Pancreatic function and diabetes
- Medical Imaging Techniques and Applications
- Nuclear Physics and Applications
- Virus-based gene therapy research
- Radiation Detection and Scintillator Technologies
- Immune Cell Function and Interaction
- Neurofibromatosis and Schwannoma Cases
- Diabetes and associated disorders
- PI3K/AKT/mTOR signaling in cancer
- Adipokines, Inflammation, and Metabolic Diseases
- Phagocytosis and Immune Regulation
- Neuroblastoma Research and Treatments
- Iron Metabolism and Disorders
- Transplantation: Methods and Outcomes
- Cardiovascular Disease and Adiposity
- Acute Myeloid Leukemia Research
- Cholesterol and Lipid Metabolism
- Heat shock proteins research
- Organ and Tissue Transplantation Research
- Aldose Reductase and Taurine
- Nerve Injury and Rehabilitation
- Apelin-related biomedical research
- Nitric Oxide and Endothelin Effects
- Spectroscopy Techniques in Biomedical and Chemical Research
Hebei Medical University
2024-2025
Northeast Forestry University
2024
Zhongda Hospital Southeast University
2013-2023
United Imaging Healthcare (China)
2023
Huazhong University of Science and Technology
2001-2018
Union Hospital
2010-2014
Tongji Hospital
2001-2003
Universidade de São Paulo
1996
UCLA Medical Center
1996
Our previous studies demonstrated that inflammation contributes to atherosclerosis through disruption of the low density lipoprotein receptor (LDLr) pathway. However, this effect is overridden by rapamycin, which an inhibitor mammalian target rapamycin (mTOR). This study investigated role mTOR pathway in vivo and vitro. To induce inflammation, we used subcutaneous injection 10% casein apolipoprotein E knockout (ApoE KO) mice lipopolysaccharide stimulation rat vascular smooth muscle cells...
Abstract Background Cold‐inducible RNA ‐binding protein ( CIRBP ) is associated with cell stress. However, its upstream regulatory factors are still largely unknown. Objectives This study investigated whether expression was regulated by transforming growth factor beta TGF ‐β) during the process of heat‐induced testicular damage. Materials and Methods Ten male adult ICR mice were allocated to heat treatment (scrotal hyperthermia at 43 °C for 30 min, n = 5) control group 5); ‐β1, ‐β2, ‐β3...
Erythropoietin (EPO), known for its role in erythroid differentiation, has been suggested to have a direct protective against variety of neurotoxic insults. In the present study, we investigated expression EPO receptor (EPOR) and number EPOR-positive cells three encephalic regions (ventral mesencephalon, striatum, cortex) following lesion induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). C57BL/6 mice underwent intraperitoneal injection MPTP at 24 h intervals 5 days, their...
Abstract Background Adipose tissue (AT) dysfunction is closely associated with obesity-related heart damage. Serpina3c which highly expressed in mature adipocytes, a secreted serine protease inhibitor that can regulate AT function. The present study aimed to investigate the effect of on and during obesity. Methods Wild type (WT) knockout (3cKO) mice were fed high-fat diet (HFD) for 20 weeks. AAV-mediated overexpression was injected locally epididymal white adipose (eWAT) examine Serpina3c....
System status of a PET scanner changes slowly but continuously with environment and aging detectors. To achieve the best imaging quality, this natural change should be compensated correctly. The traditional approach is to perform detector calibration periodically. An important normalization which estimating sensitivities lines response (LORs) usually at frequency several months. It obvious that between two adjacent calibrations, mismatch factors current system become larger may lead...
PET systems with LYSO crystals generally has a low-level discriminator (LLD) around 430 keV, to seek the balance between sensitivity and noise equivalent count rate (NECR). A lower LLD could provide higher sensitivity, but may cost of NECR greater difficulties in scatter correction (SC). However, scans expanded energy window (EEW) is possible scenario for simultaneously collecting background radiation annihilation photons. This work explores whether increased events EEW be beneficial. Monte...
The objective of this study was to evaluate the Na-K (NaK) and !he Mg (Mg) ATPase activity in presence serum normotensives (NT}, uremies (U}, essential hypertensives (EH) wth wthout addition an anti-digoxin monoclonal antibody (Ab).Seven NT (ad-lib die!}, 8 U on chronic hemodialysis die!) EH low (LSD-20mEqNa/day-7days) high salt die! (HSD-LSD+200mEqNa-7days) were studied.Patients colleeled 7th day each HT immediately befare U. lnorgan1c phosphorus (Pi) release trom reaction rat renal medulla...