A5101316087- Advanced Drug Delivery Systems
- biodegradable polymer synthesis and properties
- Advanced Glycation End Products research
- bioluminescence and chemiluminescence research
- Genetics, Aging, and Longevity in Model Organisms
- Environmental and Agricultural Sciences
- Proteins in Food Systems
- Wastewater Treatment and Nitrogen Removal
- Hydrocarbon exploration and reservoir analysis
- Ecosystem dynamics and resilience
- Forest, Soil, and Plant Ecology in China
- Constructed Wetlands for Wastewater Treatment
- Peatlands and Wetlands Ecology
- Microplastics and Plastic Pollution
- Catalytic Processes in Materials Science
- Ammonia Synthesis and Nitrogen Reduction
- Plant Ecology and Soil Science
- Drug Solubulity and Delivery Systems
- Microbial Inactivation Methods
- Membrane Separation Technologies
- Computational Drug Discovery Methods
- Enhanced Oil Recovery Techniques
- Autophagy in Disease and Therapy
- Advanced Biosensing Techniques and Applications
- Arsenic contamination and mitigation
University of Electronic Science and Technology of China
2024-2025
Changzhou University
2024
China University of Petroleum, Beijing
2024
Southwest University
2023
Guilin University of Technology
2023
Beijing Normal University
2017
Capital Medical University
2015
Capital University
2015
Shenyang Pharmaceutical University
2002-2003
L-theanine, a non-protein amino acid naturally occurring in tea leaves, is recognized for its antioxidant, anti-inflammatory, and neuroprotective properties. Despite known benefits, the mechanisms by which L-theanine influences lifespan extension remain poorly understood. This study investigated effects of on Caenorhabditis elegans explored underlying mechanisms. Our findings indicate that significantly diminishes accumulation advanced glycation end products (AGEs), are biomarkers closely...
Abstract In this study, a novel high‐temperature and high‐pressure foam evaluator with variable diameters inner cell cylinder flip function was designed on our own, which can solve the problems such as difficulties in generation inaccurate determination of various parameters by same type instruments, through foaming performance more than 10 betaine surfactants evaluated. The results show that: (1) higher pressure, rate agent stable foam, but stability foamers at low high pressures,...
C-terminal Src kinase (CSK) is the major inhibitory for family kinases (SFKs) through phosphorylation of their C-tail tyrosine site, and regulates various cellular activities in association with SFKs functions. As a cytoplasmic protein, CSK need be recruited to plasma membrane regulate activities. The regulatory mechanism activity its subcellular localization remains largely unclear. In this work, we developed genetically encoded biosensor based on fluorescence resonance energy transfer...
Glycation Stress (GS), induced by advanced glycation end-products (AGEs), significantly impacts aging processes. This study introduces a new model of GS Caenorhabditis elegans feeding them Escherichia coli OP50 cultured in glucose-enriched medium, which better simulates human dietary compared to previous single protein–glucose cross-linking methods. Utilizing WormCNN, deep learning model, we assessed the health status and calculated Healthy Aging Index (HAI) worms with or without GS. Our...
Atmospheric nitrogen deposition has increased in the last several decades due to anthropogenic activities and global changes.Increasing become an important factor regulating carbon cycle grassland ecosystems.Litter decomposition, a key process of nutrient cycling terrestrial ecosystems, is main source soil pool basis fertility maintenance.Elevated could affect litter decomposition by raising availability, increasing quantity quality inputs, altering microorganism conditions.Litter are...
A turn-on fluorescent nanoprobe was developed by grafting a coumarin-based fluorophore onto halloysite nanotubes. This probe can be used for both rapid detection and efficient removal of ClO − in pure aqueous solution.
C-terminal Src kinase (CSK) is the major inhibitory for family kinases (SFKs) through phosphorylation of their C-tail tyrosine sites, and it regulates various types cellular activity in association with SFK function. As a cytoplasmic protein, CSK needs be recruited to plasma membrane regulate SFKs' activity. The regulatory mechanism behind its subcellular localization remains largely unclear. In this work, we developed genetically encoded biosensor based on fluorescence resonance energy...
Despite the growing interest in anti-aging drug development, high cost and low success rate pose a significant challenge. We present ElixirSeeker, new machine-learning framework designed to help speed up discovery of potential compounds by utilizing attention-driven fusion molecular fingerprints. Our approach integrates fingerprints generated different algorithms utilizes XGBoost select optimal fingerprint lengths. Subsequently, we assign weights employ Kernel Principal Component Analysis...
Extracellular matrix (ECM) often becomes stiffer during tumor development, which not only gives the tumor's hardness feel but also actively contributes to formation. A good example is hepatocellular carcinoma (HCC) that usually develops within chronically stiffened liver tissues due fibrosis and cirrhosis. On other hand, HCC cells exhibit reduced autophagy in a malignancy dependent manner, suggesting suppressed development. However, it known whether ECM stiffness would influence To...
Commonly used external carbon sources in sewage treatment plants include sodium acetate (NaAc) and glucose (Glu). Previous studies have demonstrated that substituting with kitchen waste hydrolysate (KWH) can effectively enhance total nitrogen (TN) removal efficiency. However, there is a concern regarding the potential increase nitrous oxide (N2O) emissions due to introduction of complex organic loads from KWH. Hence, this study aimed compare impacts KWH, Glu, NaAc on N2O treatment. The...