A5008200593- Natural product bioactivities and synthesis
- Traditional Chinese Medicine Analysis
- Phytochemistry and Bioactive Compounds
- Phytochemistry and Biological Activities
- Fungal Biology and Applications
- Food Chemistry and Fat Analysis
- Advanced Chemical Sensor Technologies
- Phytochemical compounds biological activities
- Spine and Intervertebral Disc Pathology
- Phytochemistry and Bioactivity Studies
- Plant-based Medicinal Research
- Plant Toxicity and Pharmacological Properties
- Metabolomics and Mass Spectrometry Studies
Anhui University
2024-2025
Minzu University of China
2023-2024
Anhui University of Traditional Chinese Medicine
2023
Fuyang Normal University
2023
The ancient Chinese medical texts have recorded Guizhi Fuzi decoction (GZFZT) as a therapeutic intervention for lumbar disc herniation (LDH), and its clinical efficacy has been validated in practice. This research endeavor is specifically designed to delve into elucidate precise underlying mechanisms of action, leveraging the sophisticated methodologies network pharmacology bioinformatics. In this study, we used Traditional Medicine Systems Pharmacology Database Analysis Platform extract...
The ethnobotanical plant Marsdenia tenacissima has been used for hundreds of years Dai people in Yunnan Province, China. Previously, chemical investigations on this have revealed that pregnane glycosides were the main biological constituents. Nine new glycosides, marsdeosides A–I (1–9), isolated from cultivated dried stems medicinal study. structures analyzed by extensive spectroscopic analysis, including 1D, 2D NMR, HRESIMS, and IR analysis. absolute configurations sugar moieties identified...
The Paeonia suffruticosa, known as 'Feng Dan', has been used for thousands of years in traditional Chinese medicine. In our chemical investigation on the root bark plant, five new phenolic dimers, namely, paeobenzofuranones A-E (1-5), were characterized. Their structures determined using spectroscopic analysis including 1D and 2D NMR, HRESIMS, UV, IR, well ECD calculations. Compounds 2, 4, 5 showed cytotoxicity against three human cancer cell lines, with IC50 values ranging from 6.7 to 25.1...
The Marsdenia tenacissima, has been used as traditional Chinese medicine for six hundred years. Our chemical investigation on the stem of tenacissima led to isolation one new pregnane glycoside, namely, marsdeoside J (compound 1) and twelve known compounds. structure compound was elucidated by spectroscopic analysis including 1D 2D NMR, HRESIMS, IR, UV. absolute configurations sugar moiety were identified comparing specific optical rotations Rf values with those commercially available...
The Paeonia ostii, also known as "Feng Dan" have a crucial role in folk medicine to treat lumbar muscles strain, knee osteoarthritis and cervical spondylosis. In this study, four new phenolic compounds, specifically Paeoniaostiph A–E (1–4) compounds were characterised through spectroscopic techniques, including 1D 2D NMR, HRESIMS, UV, IR, electronic circular dichroism computations explore their structures. Cytotoxicity NO production inhibition of the studied. results cytotoxicity experiment...
This study aimed to investigate the changes of coffee bean lipids during process roasting. The lipid classes and molecular species in beans were characterized by lipidomic analysis combined with chemometrics. A total 12 105 identified quantified. content phosphatidylethanolamine (PE) lysophosphatidylethanolamine (LPE) green was obviously higher than roasted bean. Other phospholipids, such as phosphatidylinositol (PI), lysophosphatidylinositol (LPI), phosphatidylcholine (PC),...