A5110687327- Ultrasound and Hyperthermia Applications
- Glycosylation and Glycoproteins Research
- Natural product bioactivities and synthesis
- Effects and risks of endocrine disrupting chemicals
- Photoacoustic and Ultrasonic Imaging
- Hypothalamic control of reproductive hormones
- Menstrual Health and Disorders
- Ferroptosis and cancer prognosis
- Optical Network Technologies
- Retinoids in leukemia and cellular processes
- Medicinal Plant Pharmacodynamics Research
- Toxic Organic Pollutants Impact
- Acute Myeloid Leukemia Research
- Ultrasound Imaging and Elastography
- Wnt/β-catenin signaling in development and cancer
- Adrenal Hormones and Disorders
- Fluoride Effects and Removal
- Hippo pathway signaling and YAP/TAZ
- Hormonal Regulation and Hypertension
- Testicular diseases and treatments
- Nanoplatforms for cancer theranostics
- Hematopoietic Stem Cell Transplantation
- GDF15 and Related Biomarkers
- Frailty in Older Adults
- Myeloproliferative Neoplasms: Diagnosis and Treatment
Chongqing Medical University
2010-2025
Chongqing Public Health Medical Center
2024-2025
University of Hong Kong
2023-2024
The Affiliated Yongchuan Hospital of Chongqing Medical University
2024
Yangtze Optical Electronic (China)
2024
Guangxi Medical University
2024
Yangtze University
2024
University of Hong Kong - Shenzhen Hospital
2024
Yunnan University of Traditional Chinese Medicine
2024
Brigham and Women's Hospital
2023
Previous studies have found a correlation between peer attachment and Internet addiction. The three dimensions (peer trust, communication, alienation) of reflect different needs in relationships. This study used network analysis to construct model the primary aim was identify which relationship are most significantly associated with addiction adolescents. A total 782 adolescents (413 girls 369 boys, Mean age = 13.52, SD 1.17) from school participated this study. Basic demographic information...
ABSTRACT Background Acute myeloid leukemia (AML) is a malignant hematological disease that has shown an increased prevalence in recent years. Despite advancements treatment, significant limitations remain. Therefore, more information about AML mechanisms essential to improve therapeutic strategies. Methods RT‐qPCR, IHC, and western blot were used analyze SPAG6 expression levels. The association between patient survival was evaluated using LeukemiaDB, GEPIA, Bloodspot databases. Cell...
To determine the incidence and risk factors of severe infection (SI) in patients with diffuse large B-cell lymphoma (DLBCL) receiving rituximab-chemotherapy (R-C). This retrospective study was conducted at a tertiary care center China. Patients newly diagnosed DLBCL who were treated R-C between January 1, 2022, July 2023, our included this study. SI defined as an resulting hospitalization. COVID-19 infections excluded from categorized having or not by analyzing clinical data, comparing...
Background: Puberty is a life milestone that marks the transition from childhood to adulthood. An ambispective Chongqing Pubertal Timing (CQPT) cohort was started in 2014 understand pubertal timing and identify environmental risk factors. Methods: A total of 1429 children adolescents were recruited have been followed up once every 6 months for 8 years district Chongqing, China. Data collected via questionnaires social family environment, health conditions, gestational maternal information,...
Abstract Objective To investigate the effects of ulinastatin and docetaxel on invasion breast cancer cells expression uPA, uPAR ERK, MDA-MB-231 MCF-7 cells. Methods The nude mice were treated with PBS, ulinastatin, docetaxel, plus respectively. Their 1) cell ability was assayed using Transwell; 2) ERK detected by real time PCR Western blot; 3) p-ERK protein level in quantified immunohistochemistry. Results Treatment respectively, significantly inhibited invasion; mRNA levels ERK1/2 but...
This study investigated the effects of Ulinastatin (UTI) and docataxel (Taxotere, TAX) on tumor growth expression interleukin-6 (IL-6), interleukin-8 (IL-8), necrosis factor-α (TNF-α) in breast cancer.MDA-MB-231 human carcinoma cells were cultured vitro injected into nude mice to establish xenografts vivo. Cultured with tumors randomly divided four groups for treatment TAX, UTI, TAX+UTI. The these drug treatments cell proliferation apoptosis was measured using MTT assay Annexin V/propidium...
Urinary trypsin inhibitor (UTI) ulinastatin as a broad-spectrum protease has been widely used to treat acute pancreatitis and shock improve the surgical outcome in clinic. In present study, we investigated potential antihuman breast cancer effects of UTI its combination with taxotere (TXT). Human primary cells cell line MDA-MB-231 were treated or without TXT, invasion metastasis ability these evaluated, respectively, by transwell assay. Reverse transcription-polymerase chain reaction was...
Abstract Context Evidence for the associations between psychosocial stress PS related exposures and puberty timing are inconclusive. The of children has rarely been evaluated through repeated measurements. Objective To evaluate trajectories pubertal outcomes girls boys in a Chinese cohort (2015-2022). Methods Pubertal 732 688 were physically examined every 6 months. Stressful life events repeatedly assessed 7 times. A group-based trajectory model was fitted optimum total from 5 sources. Cox...
To date, the reliability of pubertal development self-assessment tools is questioned, and very few studies have explored comparison between these in longitudinal studies. Hence, this study aimed to examine using realistic color images (RCIs) Pubertal Development Scale (PDS) a cohort study.
Weakly coupled mode-division-multiplexing (MDM) systems based on intensity modulation and direct detection (IM-DD) are a good candidate for further improving the capacity of short-reach optical interconnections. However, restrained by modal crosstalk transmission link reception degenerate mode groups (DMGs) utilizing bandwidth-limited multimode photodetectors (PDs), high-speed MDM IM-DD has encountered bottleneck. In this Letter, we investigate weakly system diversity receiver scheme...
Ovarian cancer (OC) is a kind of lethiferous in gynecology, and the development chemoresistance brief reason for treatment failure. The genes which contribute to are often leading short survival. Thus, this study aims identify predictive markers survival from chemoresistant-related genes.
Emerging evidence suggests that cancer cells may disseminate early, prior to the formation of traditional macro-metastases. However, mechanisms underlying seeding and transition early disseminated (DCCs) into metastatic tumors remain poorly understood. Through single-cell RNA sequencing, we show lung DCCs from esophageal squamous cell carcinoma (ESCC) exhibit a trophoblast-like 'tumor implantation' phenotype, which enhances their dissemination supports growth. Notably, ESCC overexpressing...
Abstract The invasion and metastasis affect the survival prognosis of patients with esophageal carcinoma (ESCC). Through single-cell sequencing analysis para-cancerous tissue, tumor normal lymph node tissue in 4 untreated ESCC patients, we found that APOC1 was specifically up-regulated tissue. In vitro vivo experiments revealed overexpression significantly promoted migration anti-ferroptosis function ESCC. Also, upregulation promotes M2 macrophage differentiation, Treg aggregation, CD8 T...