A5085502355- Cerebrospinal fluid and hydrocephalus
- Spinal Dysraphism and Malformations
- Heavy Metal Exposure and Toxicity
- Fetal and Pediatric Neurological Disorders
- Arsenic contamination and mitigation
- Folate and B Vitamins Research
- Glioma Diagnosis and Treatment
- Craniofacial Disorders and Treatments
- Neonatal and fetal brain pathology
- Fluoride Effects and Removal
- Traumatic Brain Injury and Neurovascular Disturbances
- Head and Neck Surgical Oncology
- Otolaryngology and Infectious Diseases
- Intraoperative Neuromonitoring and Anesthetic Effects
- Anesthesia and Neurotoxicity Research
- Congenital gastrointestinal and neural anomalies
- Anesthesia and Pain Management
- Teratomas and Epidermoid Cysts
- Sarcoma Diagnosis and Treatment
- Electronic Health Records Systems
- Assisted Reproductive Technology and Twin Pregnancy
- Pregnancy and Medication Impact
- Prenatal Screening and Diagnostics
- Cleft Lip and Palate Research
- Neurofibromatosis and Schwannoma Cases
National Institute of Neurosciences & Hospital
2017-2024
Dhaka Shishu Hospital
2024
Bangabandhu Sheikh Mujib Medical University
2024
Neural tube defects are a pressing public health concern despite advances in prevention from folic acid-based strategies. Numerous chemicals, particular arsenic, have been associated with neural animal models and could influence risk humans.
Abstract Background Arsenic exposure has been associated with gestational diabetes mellitus. However, the extent to which arsenic during pregnancy is postpartum glucose intolerance unknown. Methods We studied 323 women in Bangladesh. assessed early via toenail and water samples. measured fasting insulin serum at a mean (SD) of 4.0 (3.5) weeks post-delivery. ran covariate-adjusted, linear regression models examine associations concentrations HOMA-IR, marker resistance, HOMA-β, beta cell...
Abstract Background Human studies of genetic risk factors for neural tube defects, severe birth defects associated with long‐term health consequences in surviving children, have predominantly been restricted to a subset candidate genes specific biological pathways including folate metabolism. Methods In this study, we investigated the association variants spanning genome spina bifida (i.e., myelomeningocele and meningocele) families enrolled from December 2016 through 2022 case–control study...
Abstract Background Spina bifida, a developmental malformation of the spinal cord, is associated with high rates mortality and disability. Although folic acid-based preventive strategies have been successful in reducing spina some areas continue to be at higher risk because chemical exposures. Bangladesh has arsenic exposures through contaminated drinking water bifida. Methods We conducted hospital-based case-control study National Institute Neurosciences & Hospital (NINS&H) Dhaka,...
Abstract Background Spina bifida, a developmental malformation of the spinal cord, is associated with high rates mortality and disability. Although folic acid-based preventive strategies have been successful in reducing spina some areas continue to be at higher risk because chemical exposures. Bangladesh has arsenic exposures through contaminated drinking water bifida. This study examines relationships between mother’s exposure, acid, bifida Bangladesh. Methods We conducted hospital-based...
Introduction: ToRCH is an acronym for four congenital infections that are sometimes difficult to distinguish: Toxoplasmosis, Rubella, Cytomegalovirus (CMV), and Herpes Simplex Virus (HSV). This group of organisms produces serious Central Nervous System (CNS) other infections, which potentially preventable treatable. Methods: Neonates infants with hydrocephalus (N = 65) identified via the outpatient department National Institute Neurosciences Hospital (NINS&H), were prospectively screened...
An emerging hypothesis linking arsenic toxicity involves altered epigenetic mechanisms, such as DNA methylation. In this study, we examined the relationship between parents' exposure and methylation in tissues obtained from 28 infants with spina bifida Bangladesh. We analyzed toenails using inductively coupled plasma mass spectrometry (ICP-MS). was measured infants' dural tissue, buccal swabs, whole blood Illumina Infinium MethylationEPIC BeadChip. performed epigenome-wide association...
Background: Posterior cranial fossa tumors are the most common in children and constitute about two-thirds of pediatric brain tumors. Such patient presents with symptoms signs raised intracranial pressure. All patients were diagnosed midline posterior hydrocephalus. The ventriculoperitoneal shunt was done before definitive surgery for all patients. Definitive later on. These followed up to 7th postoperative day following surgery. We assessed development Objectives: objective study assess...
Object: The objective of this study was to determine the relationship location ventricular catheter tip and function ventriculoperitoneal shunt. Methods: This prospective observational included 140 patients from a single institution who underwent shunt procedure in which new placed between September, 2013 September 2016. Data abstracted for each patient age, sex, diagnosis, site side placement. Postoperative CT scan images were reviewed accuracy Patients followed up over 2 ½ 4 years.63...
Sarcomas are malignant neoplasms originating from mesodermal tissues that constitute connective of the body. This seven years old girl was born after an uncomplicated full term pregnancy. Her physical status at birth unremarkable. younger sister is healthy. At age one and a half year she developed swelling over posterior head neck region gradually increasing. The rate growth more rapid October 2014. She admitted in National Institute Neurosciences & Hospital (NINS). Local examination...
Acrania is a rare congenital anomaly and characterized by partial or complete absence of the calvarium. Although acrania associated with anencephaly well recognized entity but isolated anomaly. Ultrasound allows early diagnosis this The fetus was found to have completely formed brain, base skull facial structures lacking cranium. Authors present case acrania. Bang. J Neurosurgery 2021; 11(1): 50-53
Background: Management for simple hydrocephalus in low/middle income countries include insertion of a ventriculoperitoneal shunt (VPS) or performance an endoscopic third ventriculostomy (ETV).
 Objective: This present study was carried out to compare presenting features, surgical management and outcomes patients with loculated hydrocephalus.
 Methodology: case-control performed the Department Paediatric Neurosurgery at National Institute Neurosciences Hospital, Dhaka, Bangladesh...
BACKGROUND AND AIM: The pathogenesis of spina bifida involves complex gene‒environment interactions, and folate pathway genes are the main targets interest. High prenatal arsenic exposure increases risk in experimental animals, possibly by its disruption metabolism. However, few population health studies have examined effect modification arsenic-induced genetic polymorphisms involved METHOD: We assessed genotypes 108 infants with (myelomeningocele or meningocele), 113 controls, their mothers...
A spinal epidermoid cyst is a rare congenital tumour that may be associated with dysraphism. Congenital cysts without dysraphism are rare. Here we reporting and interesting case of thoracic Intradural extra-medullary not Epidermoid (EC) represent less than 1.0% rarely seen as an intradural cord tumor. Preoperative Clinico- Radiological assumption important for surgical planning. Journal National Institute Neurosciences Bangladesh, January 2023;9(1):88-95
Intradural arachnoid cysts involving the spine are uncommon and especially rare in an anterior cervical location. In literature, among 15 patients, 8 were paediatric age group 3 patients cyst was localized to full length of spinal canal. Although they occur secondary trauma, haemorrhage, surgery or inflammation, most them known be idiopathic congenital. disease shows a dramatic neurological course, early diagnosis treatment could provide good results. group, intradural is unusual cause...
Encephalocele is defined as protrusion of cranial contents like meninges and cerebral tissue beyond the normal confines skull through a defect in cranium. It one form neural tube are anencephaly spina bifida. There 2 main types encephalomeningocele, frontoethmoidal occipital, according to location defect. The type defect, which located area frontal ethmoidal bones. authors present case frontonasal encephalocele very young child.Journal National Institute Neurosciences Bangladesh, 2018;4(1): 58-62
Background: Inaccurate placement of VP shunt catheter is related to failure.
 Objective: The objective this study was determine the accuracy ventricular during ventriculoperitoneal operations using freehand technique.
 Methodology: This prospective observational included all patients from a single institution who underwent procedure in which new placed between September 2013 and August 2016 for period three (03) years. Data abstracted each patient age, sex, diagnosis, site side...
Background: The successful correction of frontonasal encephaloceles was shown to depend on a detailed understanding the pathological anatomy, careful planning bone movements correct these deformities, and attention detail regarding placement scars, positioning medial canthi nasal reconstruction.
 Objective: We reviewed our experience at paediatric neurosurgery department national institute neurosciences, Dhaka, Bangladesh discussed evolution toward definitive, single-stage correction,...
Ventriculoperitoneal (VP) shunt is a common procedure performed for treatinghydrocephalus. Recently, endoscopy has been used in selected cases. Proximalmigration of VP rare complication. Complete intracranial migration VPshunt very with few cases reported literature. We report case ofcomplete which was endoscopically retrieved.The possible mechanisms causing this uncommon complication and themanagement are explained. Bang. J Neurosurgery 2020; 9(2): 168-172
Background: Neural tube defects, severe birth defects that occur when the neural plate fails to close in early gestation, continue be a pressing public health concern, despite advances prevention from folic acid-based strategies. Arsenic, chemical naturally occurring soils and drinking water, has been shown induce animal models could contribute humans. We investigated relationship between parental arsenic exposure risk of myelomeningocele, common form defect, case control study Bangladesh....