A5026161402- Biomarkers in Disease Mechanisms
- Essential Oils and Antimicrobial Activity
- Migraine and Headache Studies
- Sperm and Testicular Function
- Electrospun Nanofibers in Biomedical Applications
- Tissue Engineering and Regenerative Medicine
- Phytochemistry and Biological Activities
- Reproductive Biology and Fertility
- Phytochemicals and Antioxidant Activities
- Probiotics and Fermented Foods
- Animal Nutrition and Physiology
- Hepatitis B Virus Studies
- Renal and related cancers
- Allelopathy and phytotoxic interactions
- Ophthalmology and Eye Disorders
- Celiac Disease Research and Management
- Italian Literature and Culture
- RNA Interference and Gene Delivery
- COVID-19 and Mental Health
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Leptospirosis research and findings
- Pluripotent Stem Cells Research
- Innovations in Medical Education
- Mental Health Treatment and Access
- Microscopic Colitis
Shahid Beheshti University of Medical Sciences
2024-2025
University of Oslo
2024-2025
Sykehuset i Vestfold
2025
Academic Center for Education, Culture and Research
2024-2025
Islamic Azad University Medical Branch of Tehran
2025
Shiraz University of Medical Sciences
2025
Pasteur Institute of Iran
2018-2024
Iran University of Medical Sciences
2013-2024
IRCCS Humanitas Research Hospital
2021-2023
Kashan University of Medical Sciences
2023
Abstract Background The innate immune system recalls a challenge to adapt secondary challenge, phenomenon called trained immunity. Training involves cellular metabolic, epigenetic and functional reprogramming, but how broadly immunity protects from infections is unknown. For the first time, we addressed whether provides protection in large panel of preclinical models infections. Methods Mice were subjected systemic infections, peritonitis, enteritis, pneumonia induced by Staphylococcus...
The aim of this paper was to design and fabricate a novel composite scaffold based on the combination 3D-printed polylactic acid-based triply periodic minimal surfaces (TPMSs) cell-laden alginate hydrogel. This improves low mechanical properties hydrogel can also provide with suitable pore size, which be used in bone regeneration applications. In regard, an implicit function generate some gyroid TPMS scaffolds. Then fused deposition modeling process employed print Moreover, micro computed...
Skin injuries lead to a large burden of morbidity. Although numerous clinical and scientific strategies have been investigated repair injured skin, optimal regeneration therapy still poses considerable obstacle. To address this challenge, decellularized extracellular matrix-based scaffolds recellularized with stem cells offer significant advancements in skin wound healing. Herein, human placental sponge (DPS) was fabricated using the decellularization freeze-drying technique then...
Background . There have been few studies on the relation between vitamin D and migraine. We investigated prevalence of deficiency in migraine patients compared it with a control group. also evaluated relationship severity Methods 105 newly diagnosed 110 controls, matched for age, sex, socioeconomic status, education, sun exposure, were enrolled during spring 2011. 25-Hydroxy [25(OH)D] plasma levels measured by chemiluminescence immunoassay. Results The mean ± SE concentration 25(OH)D...
MIDAS is a valid and reliable short questionnaire for assessment of headache related disability. Linguistic validation Persian psychometric properties between tension type (TTH) migraine were the aims this study.Patients with or TTH included. At first visit, we administered symptom questionnaire, MIDAS, SF-36. Patients filled out in second third visit within three eight weeks after base line visit. Internal consistency (Cronbach α ) test-retest reproducibility (Spearman correlation...
Objectives: Problematic substance use is one of the most stigmatised health conditions leading research to examine how labels and models used describe it influence public stigma.Two recent studies whether beliefs in a disease model addiction stigma but result equivocal findingsin line with mixed-blessings model, Kelly et al. (2021) found that whilst label 'chronically relapsing brain disease' reduced blame attribution, decreased prognostic optimism increased perceived danger need for...
Headache Impact Test (HIT-6) measures the impact headaches in a 1-month period. We validated Persian translation of HIT-6, compared HIT-6 psychometric analysis between migraine and tension-type headache (TTH) patients, evaluated capability to differentiate TTH, chronic migraine, episodic migraine.Qualified participants, including 274 patients diagnosed with or were required complete SF-36v2, symptoms questionnaire on their first visit. At 3 8 weeks from visit, participants completed HIT-6....
Hypervariability of HCV proteins is an important obstacle to design efficient vaccine for infection. Multi-epitope vaccines containing conserved epitopes the virus could be a promising approach protection against HCV.Cellular and humoral immune responses multi-epitope DNA peptide were evaluated in BALB/c mice.In this experimental study, DNA- peptide-based infection harboring immunodominant CD8+ T cell (HLA-A2 H2-Dd) from Core (132-142), NS3 (1073-1081) NS5B (2727-2735), Th CD4+ epitope...
This study was performed to evaluate the effects of Lactobacillus acidophilus bacteria as a probiotic on chicken T cell subset populations in peripheral blood and lymphoid tissues. Thirty chickens were divided into three groups fed sterilised cow milk, mixture milk L. (probiotic), or neither, control group. Chickens euthanised after 14 21 days, whole ileal, bursal, caecal tonsillar tissues collected. The subsets, including CD4 + , CD8 TCR1 cells, evaluated by immunohistochemistry flow...
Abstract Decellularized scaffolds have been found to be excellent platforms for tissue engineering applications. The attempts are still being made optimize a decellularization protocol with successful removal of the cells minimal damages extracellular matrix components. We examined twelve procedures using different concentrations Sodium dodecyl sulfate and Triton X-100 (alone or in combination), incubation time points 15 30 min. Then, potential decellularized scaffold as three-dimensional...
Background Early prognostic stratification of patients with sepsis is a difficult clinical challenge. Aim this study was to evaluate novel molecules in association parameters as predictors 90-days mortality admitted at Humanitas Research Hospital. Methods Plasma samples were collected from 178 patients, diagnosed based on Sepsis-3 criteria, admission the Emergency Department and after 5 days hospitalization. Levels pentraxin 3 (PTX3), soluble IL-1 type 2 receptor (sIL-1R2), panel pro-...
The goal of the study was to determine which aspects interpersonal touch interactions lead a positive or negative experience. Previous research has focused primarily on physical characteristics. We suggest that this may not be sufficient fully capture complexity Specifically, we examined how fulfilment psychological needs influences experiences and relates characteristics situational factors.
Abstract Biocompatible polymer-based scaffolds hold great promise for neural repair, especially when they are coupled with electrostimulation to induce differentiation. In this study, a combination of polyacrylonitrile/polyaniline (PAN/PANI) and Carbon Nanotubes (CNTs) were used fabricate three different biomimetic electrospun (samples 1, 2 3 containing 0.26 wt%, 1 wt% CNTs, respectively). These underwent thorough characterization assessing electroconductivity, tensile strength, wettability,...
Background and Objective: Breast cancer (BC) is one of the most common cancers among women, with a high potential for metastasis. The epithelial-mesenchymal transition (EMT) crucial in invasion metastasis cells. This research was designed to examine efficacy photobiomodulation therapy combination celecoxib inhibiting EMT process. We also analyzed changes expression E-cadherin, N-cadherin, α-SMA genes BC cell lines MCF-7 MDA-MB-231. Material Methods: In this study, IC50 first determined using...
Objective: The present study aimed to carry out the molecular identification of some bacteria in seminal fluid and investigation their effects on semen quality Methods: research cohort comprised 80 infertile individuals men with no fer-tility issues. Evaluation sperm characteristics adhered protocols outlined by World Health Organization. Detection verification pathogens were carried PCR. Results: prevalence bacteriospermia group exhibited a noticeable increase compared control (p<0.05)....
ABSTRACT Introduction Social relationships and support are vital for well‐being health. In the context of metabolic bariatric surgery (MBS), these might influence emotion regulation health behaviors that affect surgical outcomes. Conversely, outcomes MBS can impact an individual's social dynamics due to enhanced engagement or potential shifts in structures resulting from changes self‐perception. Objective This study investigated bidirectional relationship between factors (MBS) outcomes,...
Migraine-specific quality of life (MSQ) is a valid and reliable questionnaire. Linguistic validation Persian MSQ questionnaire, analysis psychometric properties between chronic episodic migraine patients, capability to differentiate migraines were the aims this study.Participants selected from four different neurology clinics that diagnosed as or patients. Baseline data included information v. 2.1, MIGSEV, SF-36, symptoms At third week baseline, participants filled out MIGSEV. Internal...
Streptococcus pneumoniae is a major pathogen in children, elderly subjects, and immunodeficient patients. Pentraxin 3 (PTX3) fluid-phase pattern recognition molecule (PRM) involved resistance to selected microbial agents regulation of inflammation. The present study was designed assess the role PTX3 invasive pneumococcal infection. In murine model infection, strongly induced non-hematopoietic (particularly, endothelial) cells. IL-1β/MyD88 axis played Ptx3 gene expression. −/− mice presented...