- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Protein Structure and Dynamics
- Hemoglobin structure and function
- Medical Imaging and Pathology Studies
- Immune Response and Inflammation
- Glioma Diagnosis and Treatment
- Cerebrovascular and Carotid Artery Diseases
- Oral and Maxillofacial Pathology
- Gastrointestinal disorders and treatments
- Dental materials and restorations
- Spine and Intervertebral Disc Pathology
- Cancer Diagnosis and Treatment
- Enzyme Structure and Function
- Dental Radiography and Imaging
- Acute Ischemic Stroke Management
- Artificial Intelligence in Healthcare and Education
- Testicular diseases and treatments
- Reconstructive Facial Surgery Techniques
- Ion Transport and Channel Regulation
- Polysaccharides Composition and Applications
- Electron Spin Resonance Studies
- Spectroscopy and Quantum Chemical Studies
- Material Properties and Processing
- Medical Imaging and Analysis
Kyoto Prefectural University of Medicine
2009-2025
Indiana University – Purdue University Indianapolis
2024
Kyoto first Red Cross hospital
2022
Kyoto Prefectural University
2020
Kobe Central Hospital
2016-2017
Nara Institute of Science and Technology
2016
Keio University
2009-2013
Osaka City University
1993
BACKGROUND Schwannomas typically show slow growth and a low risk of recurrence. The authors report rare case 56-year-old woman with spinal schwannoma that exhibited rapid recurrence an atypically high Ki-67 index (8.9%), suggesting more aggressive behavior than usually observed in benign schwannomas. OBSERVATIONS patient initially presented worsening back right sciatic nerve pain, resulting difficulty walking independently. MRI revealed dumbbell-shaped tumor compressing the cauda equina. A...
Abstract Purpose To evaluate the shade variability and stability of interim definitive tooth‐colored restorative materials by comparing manufacturer‐claimed shades to a universal guide before after thermocycling. Materials Methods Eight commercially available were tested, including conventional, milled, 3D‐printed types. Each material was categorized into three subgroups (A1, A2, A3), with 10 samples per subgroup. The color differences (Δ E 00 ) between materials’ (VITA classical A1‐D4)...
Objectives: To examine the effects of surface treatments on color stability, roughness, gloss, and wettability monolithic polychromatic material jetting (MJT) 3D-printed denture material. Material Methods: Twenty-one variants same (TrueDent; Stratasys, Eden, MN, USA) underwent two (polishing only or polishing glazing), creating 42 study groups with a total 420 samples (n = 10 per group). The were manufactured using PolyJet 3D printer (J5 DentaJet; USA), type MJT printer. Color measurements...
Abstract Purpose To examine the color stability of 3D‐printed and milled, interim, definitive, restorative materials after immersion in artificial saliva wine for 1, 3, 6 months. Material Methods The study used a 2 × 5 factorial design with 10 subgroups, including liquids (artificial wine) manufacturing technology material combinations ( n = 10). Color measurements were taken using contact‐type digital spectrophotometer (CM‐2600d Spectrophotometer; Konica Minolta Healthcare Americas Inc)...
A new relaxation mode analysis method, which is referred to as the principal component has been proposed handle a large number of degrees freedom protein systems. In this carried out first and then applied small components with fluctuations. To reduce contribution fast modes in these efficiently, we have also method using multiple evolution times. The two times an all-atom molecular dynamics simulation human lysozyme aqueous solution. Slow corresponding appropriately estimated, demonstrating...
Polyfluorenes are well-known derivatives that exhibit electrical conductivity, electroluminescence, and liquid crystallinity, but its crystallization process is not well understood. To investigate the role of intra-CH/π interaction in process, 2,7-dibromo-9,9′-dialkylfluorenes (DBFs) with various dialkyl side chains (alkyl group = methyl, ethyl, n-propyl, n-butyl, n-pentyl, n-hexyl, n-octyl, 2-methylpropyl, 2-ethylbutyl) were prepared. Systematic observation single-crystal structure revealed...
The release behavior of prednisolone from hydrogels prepared with xanthan and locust bean gums was investigated. Newly developed equipment employed in order to increase the gum concentration hydrogels. apparent rate decreased increasing concentration, suggesting that diffusion drug molecules mainly controlled by density three-dimensional network structure matrix. effect additives such as glycerin sucrose on also investigated detail. Drug significantly lowered addition these compounds A...
A 77-year-old woman with chronic iron deficiency anemia had a medical examination in May 2002. She was diagnosed as having anisakiasis after upper endoscopy of the antrum stomach, and worm removed. Three years later, an showed several worms first second portions duodenum, but there were no symptoms. Ten live removed using standard biopsy forceps identified by microscopic hookworm (Ancylostoma duodenale).
Abstract The effect of hydrostatic pressure on the paracellular ion conductance (Gp) composed Na + (G ) and Cl − has been Investigated. Gp, G were time‐dependently increased after applying an osmotic gradient generated by NaCl with basolateral hypotonicity. Hydrostatic (1–4 cm H 2 O) applied from side enhanced gradient‐induced increase in a magnitude‐dependent manner, while apical diminished . How influences under isosmotic condition was also investigated. stably constant application sucrose...
The effects of shikonnin (SK) and its optical isomer alkannin (AK) on the hydroxyl radical (HO.) generation system including iron ions were evaluated using spin trap method by ESR spectroscopy. 5,5-Dimethyl-1-pyrroline-1-oxide (DMPO) was used as a agent HO. generated reaction between an ion hydrogen peroxide, which is called Fenton system. SK inhibited adduct (DMPO-OH) yielded in dose-dependent manner. In this effect no difference observed AK. When different concentrations DMPO for...
In previous studies on the nasal administration of human fibroblast interferon (HuIFN-beta), only rabbits have been used. Therefore, this route was investigated in mice, rats, and dogs. HuIFN-beta could be delivered across mucosa dogs, when it mixed with sodium glycocholate as an absorption promoter. However, pattern plasma concentration-time curve different from that rabbits. Rabbits gave highest value maximum concentration (Cmax), but declined rapidly thereafter, upon powder dosage form...
We compare two cases of primary spinal atypical teratoid/rhabdoid tumor (AT/RT), which rarely occurs in adults marked by SMARCA4 inactivation, and SMARCB1 inactivation for pediatric cases. AT/RT represents a highly malignant neoplasm comprising poorly differentiated constituents rhabdoid cells, with (INI1) or infrequently (BRG1) inactivation. These tumors are predominantly found children but rare adults. While can arise anywhere the central nervous system, cord localization is comparatively...
Abstract Background Low body weight is known to be a bleeding risk in the anticoagulation treatment. ONCO DVT study revealed that 12-month edoxaban treatment for cancer patients with isolated distal deep vein thrombosis (DVT) reduced composite outcome of symptomatic recurrent venous thromboembolism (VTE) or VTE-related death compared 3-month However, efficacy and safety long-term low unclear. Purpose In this subgroup analysis, we assessed DVT. Methods We conducted post-hoc analysis patients....
Abstract Although there are difficulties with using intraoral scans for implant‐supported complete‐arch fixed dental prostheses (ISCFDPs), several commercially available systems have become helpful in simplifying the treatment process prosthetic phase. These help patients move from interim ISCFDPs to receiving definitive just three clinical visits. This report summarizes indications, benefits, and limitations of four systems. The information provided this about digital workflow aims...
Mobile lesions of the carotid artery, which can generally be found by ultrasonography (US), are treated as unstable plaque. ≥2 mm in diameter were observed for 7 patients (6 men, 1 woman) our hospital between January 2002 and July 2015. Mean age was 67.8 years (range, 52-84 years). Diagnosis major stroke patient transient ischemic attack/minor 6 patients. Surgical treatment performed cases: endarterectomy 4 artery stenting 2. The remaining did not undergo surgery because a marked reduction...