A5013827710- Lung Cancer Diagnosis and Treatment
- Ovarian function and disorders
- Lung Cancer Treatments and Mutations
- Pleural and Pulmonary Diseases
- Reproductive Biology and Fertility
- Tracheal and airway disorders
- Esophageal and GI Pathology
- Radiomics and Machine Learning in Medical Imaging
- Assisted Reproductive Technology and Twin Pregnancy
- Reproductive System and Pregnancy
- Birth, Development, and Health
- Per- and polyfluoroalkyl substances research
- Myasthenia Gravis and Thymoma
- Nanoplatforms for cancer theranostics
- Muscle activation and electromyography studies
- Esophageal Cancer Research and Treatment
- Congenital Diaphragmatic Hernia Studies
- Photodynamic Therapy Research Studies
- Evacuation and Crowd Dynamics
- Stroke Rehabilitation and Recovery
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Ectopic Pregnancy Diagnosis and Management
- RNA modifications and cancer
- Hydraulic Fracturing and Reservoir Analysis
- Autophagy in Disease and Therapy
First Hospital of Lanzhou University
2022-2025
Lanzhou University
2022-2025
Shenzhen University
2024-2025
Guangzhou Medical University
2024-2025
China Agricultural University
2025
State Key Laboratory of Respiratory Disease
2024-2025
Shanghai Pulmonary Hospital
2016-2024
Tongji University
2016-2024
Harbin Medical University
2020-2024
Heilongjiang University of Chinese Medicine
2018-2024
High crop yields require adequate nutrients, particularly nitrate (N) and phosphorus (P). Identifying regulators for efficient N-P utilization is critical in wheat. To explore interactions, we analyze root transcriptomes under varying supplies identify TaTCP6 as a potential regulator. Nitrate-stimulated directly triggers the expression of genes related to nitrogen utilization. competes with TaSPX1/4 release TaPHR2, also interacts TaPHR2 enhance transactivation capacity downstream genes....
Abstract Owing to its difficulty in degrading and ease of accumulation the body, perfluorooctanoic acid (PFOA) has a detrimental effect on reproduction. This study aimed examine PFOA concentration follicular fluid during ovulation stimulation embryo quality impact exposure metabolic components fluid. was single-center prospective that included 25 patients with diminished ovarian reserve (DOR), normal (NOR), polycystic ovary syndrome (PCOS). Follicular samples were analyzed using ultra-high...
To investigate the impact of endometrial thickness on embryo transfer(ET) day clinical pregnancy outcomes frozen-thawed transfer cycles which have undergone hormone replacement therapy(HRT-FET).A total 10,165 HRT-FET performed between January 2013 to December 2017 in Reproductive Medicine Center Henan Provincial People's Hospital were studied retrospectively. All patients grouped according their ET (each group having an increment 1mm two neighboring groups). Multivariate regression analysis,...
To evaluate the feasibility and safety of sleeve lobectomy after neoadjuvant therapy by assessing postoperative morbidity.
Degeneration of ovarian function is an obvious feature female aging. In addition, studies have shown that autophagy decreases with age, and DNA methylation a hallmark epigenetic pattern during However, it not clear whether the expression genes are involved in declines occur aging.Three groups rats were used: 6-month-old (6 M) rats, 12-month-old (12 24-month-old (24 rats. Serum E2 levels mRNA protein Atg5, Atg12, Atg16L, Beclin1 Lc3B significantly decreased aged Atg5 gene increased The Dnmt1...
Mesenchymal stem cells-derived extracellular vesicles (MSCs-EVs) can improve intervertebral disc degeneration (IDD). Considering that, their concrete mechanisms from microRNA-194-5p/tumor receptor-associated factor 6 (miR-194-5p/TRAF6) axis in IDD ask for disclosure a scientific way.Nucleus pulposus (NP) cells and MSCs were obtained. EVs isolated the obtained identified. miR-194-5p expression MSC-EVs was altered by sequence transfection. Subsequently, MSCs-EVs co-cultured with NP intervened...
Objective To compare the cumulative live birth rate (CLBR) of a gonadotropin-releasing hormone (GnRH) antagonist regimen and progestin-primed ovarian stimulation (PPOS) in low-prognosis patients according to POSEIDON criteria. Design Single-center, retrospective, observational study. Setting Henan Provincial People’s Hospital, Zhengzhou, China Patients Women aged ≤40 years, with body mass index <25 kg/m 2 , who underwent vitro fertilization (IVF) or intracytoplasmic sperm...
Tryptophan (TRP) and its indole metabolites exhibit numerous biological effects, especially their antioxidant properties. This study used untargeted metabolomics in conjunction with targeted to investigate the differential expression of tryptophan follicular fluid (FF) diminished ovarian reserve (DOR) normal (NOR) populations. included patients DOR (n = 50) females NOR 35) who received vitro fertilization embryo transfer. Untargeted suggests that affects metabolic profile FF, TRP were...
Abstract The life‐threatening colorectal cancer exhibits multilevel immunosuppressive characteristics, including low immunogenicity, abnormal cellular metabolism, and acidic microenvironment. In this work, multi‐synergistic chemotherapeutic drug assemblies are fabricated to activate immunotherapy by modulating the characteristics. Without any excipients, glycolysis inhibitor of lonidamine (LON), indoleamine 2,3‐dioxygenase 1 (IDO‐1) NLG919 (NLG), photosensitizer chlorine e6 could...
The swift and accurate identification of motor unit spike trains (MUSTs) from surface electromyography (sEMG) is essential for enabling real-time control in neural interfaces. However, the existing sEMG decomposition methods, including blind source separation (BSS) deep learning, have not yet achieved satisfactory performance, due to high latency or low accuracy. This study introduces a novel high-density (HD-sEMG) algorithm named ML-DRSNet, which combines multi-label learning with residual...
This study was aimed to investigate potential benefits of thoracoscopic surgery for intralobar pulmonary sequestration in adult patients terms short-term surgical outcomes when compared with open surgery.Data 110 consecutive undergoing or from January 2000 December 2015 at our institution were reviewed. A total 42 video-assisted thoracic cases and 68 identified. Perioperative between evaluate efficacy.Neither group had mortality. Although the overall morbidity without statistical...
This phase I study aimed to evaluate the antitumor effect and safety of programmed death-ligand-1 (PD-L1)-targeting autologous chimeric antigen receptor T (CAR-T) cells for patients with non-small cell lung cancer (NSCLC).Programmed death-ligand-1-specific CAR-T were generated using lentiviral transduction. Four NSCLC recruited, but only one patient was finally involved. infused on three different days (total dose during therapy, 1 × 106 kg-1 body weight). The date which received first...
Although chest tube-omitted video-assisted thoracoscopic surgery (VATS) has been proven to be safe and efficacious, its universal application is precluded by a varying morbidity rate due lack of standardization. Since digital drainage already shown improved accuracy consistency in the management postoperative air leak, we incorporated it strategy intraoperative tube withdrawal, aiming achieve better results.We collected clinical data 114 consecutive patients who underwent elective uniportal...
T4N0-1 non-small-cell lung cancer (NSCLC) was historically considered curable but now includes tumours of size >7 cm according to the 8th edition tumour, node and metastasis (TNM) staging. This study set out evaluate role surgery predictors long-term survival after in this renewed group patients.Patients, with clinical T4N0-2M0 NSCLC diagnosed 2010-2013, National Cancer Database were queried. A Cox regression analysis applied investigate independent 1588 N0-1 surgical cases. For previous T3...