A5073908064- Silk-based biomaterials and applications
- Insect Resistance and Genetics
- Viral Infectious Diseases and Gene Expression in Insects
- Insect Utilization and Effects
- Neurobiology and Insect Physiology Research
- Invertebrate Immune Response Mechanisms
- Calpain Protease Function and Regulation
- Silkworms and Sericulture Research
- Insect symbiosis and bacterial influences
- Signaling Pathways in Disease
- Impact of Technology on Adolescents
- Digital Mental Health Interventions
- RNA and protein synthesis mechanisms
- Alcohol Consumption and Health Effects
- Autophagy in Disease and Therapy
- COVID-19 and Mental Health
- Traumatic Brain Injury and Neurovascular Disturbances
- RNA modifications and cancer
- Mosquito-borne diseases and control
- Lipid metabolism and biosynthesis
- Traumatic Brain Injury Research
- RNA Research and Splicing
- Insect-Plant Interactions and Control
- Entomopathogenic Microorganisms in Pest Control
- Insect and Pesticide Research
Soochow University
2023-2025
Brigham and Women's Hospital
2023
Harvard University
2023
National Institutes for Food and Drug Control
2021-2022
Peking University
2021-2022
Jiangsu University of Science and Technology
2020
Background and Objectives COVID‐19‐related quarantine stress have likely escalated the crisis of Internet addiction. This study aimed to determine impact COVID‐19 pandemic on use related risk factors among general public in China. Methods A large‐sample cross‐sectional online survey was conducted from March 24 April 30, 2020, China, 20,472 participants completed survey. We investigated prevalence severity addiction based Addiction Test (IAT), explored increases time spent addiction, as well...
Abstract Chlorantraniliprole (CAP) is a novel amide insecticide widely used in agriculture. Trace residues of CAP the environment pose threat to development and metamorphosis silkworm ( Bombyx mori ). However, mechanisms by which exposure disrupts insect remain poorly understood. This study investigated levels intracellular Ca 2+ 20‐hydroxyecdysone (20E) following low concentrations CAP. The results revealed that both directly caused increased indirectly promoted an increase inducing...
The Duox-ROS defense system plays an important role in insect intestinal immunity. To investigate the of microbiota regulation herein, 16S rRNA sequencing technology was utilized to compare characteristics bacterial populations midgut silkworm after different time-periods treatment with three feeding methods: 1-4 instars artificial diet (AD), mulberry leaf (ML) and 1-3 + 4 instar (TM). results revealed simple AD group whilst were abundant variable ML TM silkworms. By analyzing relationship...
Abstract Florfenicol (FF) is a new antibiotic commonly used in sericulture. This study aimed to examine the effects of low (LC: 0.06 g/L), medium (MC: 0.12 and high (HC: 1.2 g/L) concentrations FF on midgut physiological functions silkworm, Bombyx mori (L.) (Lepidoptera: Bombycidae). The results showed that body weight whole cocoon silkworms decreased development duration fifth instar was prolonged HC group. structure intestinal microbiota silkworm larvae changed by exposure. Specifically,...
Abstract Starvation can induce autophagy and apoptosis in intestinal cells. To elucidate the underlying mechanisms, we investigated midgut of model insect, silkworm ( Bombyx mori ), focusing on calcium homeostasis. The results indicated that body weight silkworms decreased, along with damage to morphology their digestive tracts midguts after starvation treatment. Additionally, mitochondrial swelling, were observable. Further investigation revealed upregulated transcription Ca 2+ release...
The novel pesticide chlorantraniliprole (CAP) is widely used for pest control in agriculture, and the safety non-target organisms of trace residues environment has received widespread attention. In present study, exposure to low concentrations CAP resulted abnormal silk gland development B. mori induced release intracellular Ca2+ addition triggering Ca2+-dependent gene transcription. Moreover, treatment group exhibited down-regulation oxidative phosphorylation antioxidant enzyme-related...
Abstract The silkworm, Bombyx mori , is a complete metamorphosed economic insect, and the silk gland significant organ for protein synthesis secretion. completely degenerates during pupation, but regulatory mechanism of programmed cell death (PCD) has not yet been understood. In present study, we investigated non‐genetic pathway 20E‐induced PCD in posterior (PSG) based on intracellular Ca 2+ levels. Silk morphology index indicated rapid degeneration metamorphosis from mature silkworm (MS) to...
Chlorantraniliprole (CAP), a new amide insecticide, has been widely used in agricultural production. Its trace residues the environment pose threat to non-target biological organisms such as silkworm. CAP exposure was reported cause pupation metamorphosis defects and intracellular Ca2+ imbalance. It is known that 20-hydroxyecdysone (20E) modulates Fushi-tarazu factor 1 (Ftz-f1) promote metamorphosis. However, regulatory mechanism of on Ftz-f1 remains unclear. The present study revealed...
Bacillus thuringiensis (Bt) has been extensively applied in agricultural pest management, posing a notable ecological risk to beneficial insects like Bombyx mori (silkworms). However, the toxicological mechanisms of Bt at low concentrations on silkworms remain largely unexplored. In this study, we determined LC50 (96 h) for fifth-instar silkworm larvae be 0.08 × 10−3 mg/L. Exposure sub-lethal concentration (1/2 LC50) led significant reductions body weight, pupal size, and weights both whole...