A5004755437- Bone health and osteoporosis research
- Vitamin D Research Studies
- Genetic factors in colorectal cancer
- Diet and metabolism studies
- Cancer, Lipids, and Metabolism
- Parathyroid Disorders and Treatments
- Nutritional Studies and Diet
- Prosthetics and Rehabilitation Robotics
- Diabetic Foot Ulcer Assessment and Management
- Orthopedic Surgery and Rehabilitation
- Musculoskeletal pain and rehabilitation
- Vitamin C and Antioxidants Research
- Bone health and treatments
- Alkaline Phosphatase Research Studies
- Veterinary Orthopedics and Neurology
- Noise Effects and Management
- Agriculture Sustainability and Environmental Impact
- Facial Trauma and Fracture Management
- Metabolism, Diabetes, and Cancer
- Spinal Fractures and Fixation Techniques
- Cancer-related molecular mechanisms research
- Climate Change and Health Impacts
- Health Promotion and Cardiovascular Prevention
- HIV-related health complications and treatments
- Primary Care and Health Outcomes
University of Jyväskylä
2009-2025
University of Helsinki
1993-2018
Helsinki University Hospital
2018
Minerva Foundation
1993-2000
Public Health Institute
1998
To evaluate the contribution to peak bone mass of exercise, smoking, and calcium intake in adolescents young adults.Prospective cohort study with end point measurement (bone mineral density) after 11 years' follow up for lifestyle.Five university hospital clinics.264 (153 females, 111 males) subjects aged 9 18 years at beginning 20 29 time density.Bone density lumbar spine femoral neck by dual energy x ray absorptiometry; measures physical activity smoking estimates repeated three times...
Abstract We studied the effects of a single oral phosphate (Pi) dose as well those three consecutive doses on calcium and bone metabolism. In first part study (P1 study) 10 female volunteers were given orally 1500 mg Pi in water, dose, or plain water randomized order at two different sessions. second (P3 study), Pi, separate 500 order. Calcium metabolism was monitored for 24 h by measuring concentrations serum ionized (S-iCa), urinary calcium, (S-P), P, intact parathyroid hormone (PTH),...
<title>Abstract</title> <bold>Background</bold> Lynch syndrome is a genetic cancer-predisposing caused by pathogenic mutations in DNA mismatch repair (path_MMR) genes. Due to the elevated cancer risk, novel screening methods, alongside current surveillance techniques could enhance risk stratification. Here we show how multi-omics integration be utilized pinpoint cancer-predicting biomarkers Syndrome. We studied which blood-based circulating microRNAs and metabolites predict Syndrome...
Thus far the search for osteoporosis candidate genes has focused less attention on regulation of calcium homeostasis. Associations vitamin D receptor (VDR) FokI, calcium-sensing (CaSR) A986S and parathyroid hormone (PTH) BstBI polymorphisms with homeostasis peripheral bone density were investigated in adult Finns.The subgroup population-based FINRISK survey consists 339 healthy adults aged 31-43 years. Lifestyle data assessed questionnaires food diaries. DNA was isolated from blood,...
Objective: To evaluate the effects of a low-frequency sound wave therapy programme on functional capacity, blood circulation and bone metabolism frail elderly. Design: Single-blind, randomized, controlled trial. Setting: Two senior service centres. Subjects: Forty-nine volunteers (14 males 35 females) aged 62—93 years with up to 12 diagnosed diseases were allocated in either intervention group (n = 30) or control 19). Intervention: The underwent therapy, 3—5 times week for 30 minutes per...
Abstract Circulating metabolites systemically reflect cellular processes and can modulate the tissue microenvironment in complex ways, potentially impacting cancer initiation processes. Genetic background increases risk individuals with Lynch syndrome; however, not all carriers develop cancer. Various lifestyle factors influence syndrome risk, choices actively shape systemic metabolism, circulating serving as mechanical link between risk. This study aims to characterize metabolome of...
To report the protocol of a study evaluating efficacy transdermal oestradiol (E2) gel in reducing adverse effects androgen deprivation therapy (ADT), specifically on sexual function, and to assess utility E2 combination with supervised exercise.
Sensitiivisiä henkilötietoja, kuten terveyttä tai sairautta koskevia tietoja, voidaan joissain tapauksissa käsitellä tutkimuksessa oikeudellisiin perusteisiin nojaten ilman tutkittavan henkilön erillistä suostumusta. Tieteellisen tutkimuksen toteuttaminen voi olla terveystietojen käsittelyyn riittävä peruste edellyttäen, että tutkimus toteutetaan lainsäädäntöä noudattaen. Sensitiivisten keräämistä ja säilyttämistä ohjaa kotimaisten kansainvälisten lakien lisäksi tutkimuseettiset...