A5001392681- Maternal and fetal healthcare
- RNA Research and Splicing
- Pregnancy and preeclampsia studies
- Congenital Diaphragmatic Hernia Studies
- Cancer-related molecular mechanisms research
- RNA modifications and cancer
Fuling Center Hospital of Chongqing
2023-2025
Chongqing Medical University
2025
Chongqing University
2025
Abstract Background Pseudogene‐derived lncRNAs are widely dysregulated in cancer. Technological advancements have facilitated the functional characterization of increasing pseudogenes cancer progression. However, association between and RNA N6‐methyladenosine (m 6 A) modification cancer, as well underlying mechanisms, remains largely unexplored. Methods We analyzed expression 12 146 comprehensively examined m A RNAs derived from them their paralogs. Through integrative analysis multi‐omics...
Ovarian cancer has the highest mortality rate among gynecologic tumors worldwide, with unclear underlying mechanisms of pathogenesis. RNA-binding proteins (RBPs) primarily direct post-transcriptional regulation through modulating RNA metabolism. Recent evidence demonstrates that RBPs are also implicated in transcriptional control. However, role and mechanism RBP-mediated tumorigenesis remain largely unexplored. Here, we show RBP heterogeneous ribonucleoprotein L (hnRNPL) interacts chromatin...
Abstract Objective :Pernicious placenta previa (PPP) is a special type of previa, which emphasizes that the attaches to scar uterus [1] , and has high risk adhesion, implantation fatal bleeding.PPP requires cesarean section terminate pregnancy, often endangers life parturient due excessive bleeding during operation. Therefore, how take effective measures reduce operation key rate hysterectomy mortality.In order solve this problem, we propose apply new surgical method--uterine tone-preserving...