- Semiconductor materials and devices
- Rough Sets and Fuzzy Logic
- Data Mining Algorithms and Applications
- Ferroelectric and Negative Capacitance Devices
- Advanced Memory and Neural Computing
- Aldose Reductase and Taurine
- Enzyme Structure and Function
- Traffic control and management
- Integrated Circuits and Semiconductor Failure Analysis
- Heat Transfer and Boiling Studies
- Imbalanced Data Classification Techniques
- Electronic Packaging and Soldering Technologies
- Antenna Design and Analysis
- Advancements in Semiconductor Devices and Circuit Design
- Heat Transfer and Optimization
- Transportation Planning and Optimization
- 3D IC and TSV technologies
- 14-3-3 protein interactions
- Herbal Medicine Research Studies
- Distributed Sensor Networks and Detection Algorithms
- Algorithms and Data Compression
- MXene and MAX Phase Materials
- Traffic Prediction and Management Techniques
- Gene expression and cancer classification
- Olfactory and Sensory Function Studies
Fred Hutch Cancer Center
2025
Rochester Institute of Technology
2022-2024
National Taiwan University
2014-2019
National Yang Ming Chiao Tung University
2017-2018
Feng Chia University
2017
Element Six (United States)
2016
Kaohsiung Medical University
2009-2015
Yuan Ze University
2010-2012
National University of Kaohsiung
2007-2009
Taipei Medical University
2009
In this work, we demonstrate a wavelength-tunable erbium-doped fiber (EDF) ring laser with stable single-longitudinal-mode (SLM) output. Here using the self-injection method and unpumped EDF-based saturable absorber can suppress other densely sidemode to achieve SLM. Hence, output power optical signal-to-noise ratio of proposed EDF are between -7.1 2.1 dBm 30.1 36.5 dB in tuning range 1525.0 1574.0 nm, respectively. According structure, wavelength operation extend shorter L-band from C-band....
ABSTRACT It is of substantial scientific interest to detect mediators that lie in the causal pathway from an exposure a survival outcome. However, with high‐dimensional mediators, as often encountered modern genomic data settings, there lack powerful methods can provide valid post‐selection inference for identified marginal mediation effect. To resolve this challenge, we develop procedure maximally selected natural indirect effect using semiparametric efficient influence function approach....
In this work, a compact and novel ferroelectric (FE) programmable majority gate is proposed its application in Binary Neural Network (BNNs) investigated. We demonstrate: i) by integrating N metal-ferroelectric-metal (MFM) capacitors on the of transistor (1T-N-MFM structure), nonvolatile (MAJ) that performs MAJ AND between input polarization realized; ii) validation functionality our 3-input through comprehensive theoretical experimental investigations; iii) implementation XNOR leverages only...
A simple yet practical antenna structure composed of a regular half-wavelength dipole with coupling arms is presented. Adjustment the amount to main through physical dimensions enables operation in either dual-band or wideband mode. Omni-directional radiation patterns can be achieved for both modes. The proposed has been implemented mid- and upper-bands WiMAX system. Good agreement between simulation measurement results observed.
Numerous breast cancer patients who achieve an initial response to HER-targeted therapy rapidly develop resistance within one year, leading treatment failure. Observations from clinical samples indicate that such correlates with increase in Src, EGFR, and PI3K/Akt activities a decrease PTEN activity. Furthermore, Akt survival signaling activation is also found tumors treated by toxic chemotherapeutic agents. Because cotreatment PI3K inhibitor promising strategy delay acquired preventing...
In this work, we exploit a 2TnC ferroelectric random access memory (FeRAM) cell design to realize the quasi-nondestructive readout (QNRO) of polarization ( <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">${P}_{\text{FE}}$ </tex-math></inline-formula> ) in capacitor, which can relax endurance requirement thin film and exploits benefits both FeRAM FET (FeFET). We demonstrate that: i) QNRO sensing is conducted...
S ‐Petasin is the main sesquiterpene of Petasites formosanus , a traditional folk medicine used to treat hypertension, tumors and asthma in Taiwan. The aim present study was investigate its inhibitory effects on phosphodiesterase (PDE) 1–5, ovalbumin (OVA)‐induced airway hyperresponsiveness (AHR) murine model allergic asthma. concentration‐dependently inhibited PDE3 PDE4 activities with 50% concentrations (IC 50 ) 25.5, 17.5 μ M, respectively. According Lineweaver‐Burk analysis, ‐petasin...
In this paper, we propose two path-based MAXBAND models for solving signal synchronization problems coordinated traffic signalization systems. the first proposed model (RM1), relax assumptions that lengths of common cycle, as well green splits, are fixed in base model. These factors considered decision variables RM1, which leads us to a generalized offset optimization problem. second (RM2), further free-flow speed assumption used estimating link travel times system. Since can only be reached...
Compounds from Lingzhi has been demonstrated the ability for inhibiting tyrosinase (a key enzyme in melanogenesis) activity. In this study, we investigated anti-melanogenic activity submerged mycelial culture of Ganoderma weberianum and elucidated skin lightening mechanism by B16-F10 murine melanoma cells. From cellular context, several fractionated mycelium samples exhibited reducing more than 40% extracellular melanin content particular, chloroform extract (CF-F3) inhibited both secreted...
With more phonons carrying the energy in lattice, phonon density of states diamond extends to a much higher frequencies than that any other material. This is related Debye temperature diamond, being highest bulk materials and having sound velocity known materials. However, thermal conductivity not only depends on number how fast they are, but also long can travel without disturbed or scattered. The measurement this length Mean Free Path phonons, l, which lattice through 3-phonon processes...
In this study, a process is developed for the fabrication of buried top-gated graphene transistors with Al2O3 as gate dielectric, yielding devices that can be suitable not only flexible electronics but also laser-induced (LIG)-based technology implementations. A new processing option presented use tetraethyl-orthosilicate (TEOS) an etch stop contact via etching Al2O3. Buried locally gated Al/Al2O3 field-effect (GFETs) are fabricated Dirac points low 4 V, metal-to-graphene resistance ∼1.7...
As NAND flash memory has become a major choice of storage media in diversified computing environments, the performance issue been extensively addressed many excellent designs. Among them, an effective strategy is to adopt multiple channels and flash-memory chips improve on data accesses. However, degree access parallelism cannot be increased by simply increasing number device, because it seriously limited maximum current constraint bus interface affected patterns user data. consequence,...
In this work, we study ferroelectric capacitor memories and demonstrate comparative advantages of 2T-nC (Two transistors-n metal-ferroelectric-metal (MFM) capacitors) in scalability, reliability, feasibility dense 3D integration operation. We show that: i) the sensing scalability issues conventional 1T-1C FeRAM rooted its charge-based sensing; ii) FeMFET suffers from poor reliability scaling challenges; iii) structure can be exploited to address their density reliability; iv) through...
Advanced electronics technology is moving towards smaller footprints and higher computational power. In order to achieve this, advanced packaging techniques are currently being considered, including organic, glass, semiconductor-based substrates that allow for 2.5D or 3D integration of chips devices. Metal-core a new alternative with similar properties those but the added benefits flexibility metal ductility. This work comprehensively compares thermal novel metal-based substrate, molybdenum,...
Diffusion models have demonstrated significant promise in various generative tasks; however, they often struggle to satisfy challenging constraints. Our approach addresses this limitation by rethinking training-free loss-guided diffusion from an optimization perspective. We formulate a series of constrained optimizations throughout the inference process model. In each optimization, we allow sample take multiple steps along gradient proxy constraint function until can no longer trust proxy,...
Accelerated thermal cycling (ATC) test, though time-consuming, is currently the most widely used reliability test for electronic components. However, a much faster mechanical bend often adopted as an alternative ATC test. But it general guideline that results are meaningful only if stresses applied on components either same or identical to those found in stress machines were just purposes material machines. Normally, could apply half of full cycles (from heating cooling) not even dwell time...
In the past, researchers usually assumed databases were static and items lay on same level to simplify mining problem. Modification of records with item taxonomy is, however, commonly seen in real-world applications. this paper, we thus attempt extend Han Fu's approach our previous concept pre-large itemsets maintain discovered multiple-level association rules for record modification. The is used reduce need rescanning original save maintenance costs. A itemset not truly large, but promises...
<p>In this work, we propose a 2TnC ferroelectric random access memory (FeRAM) cell design to realize the quasi- nondestructive readout (QNRO) of polarization (PFE) in capacitor, which can relax endurance requirement thin film and exploits benefits both FeRAM FET (FeFET). We demonstrate that: i) QNRO sensing PFE is conducted successfully experiment with ON/OFF ratio (ION/IOFF)>103, ION>10 μA, read endurance>106 cycles, by 106x; ii) optimization performance be realized tuning...