A5085572834- Adipose Tissue and Metabolism
- Nutritional Studies and Diet
- Adipokines, Inflammation, and Metabolic Diseases
- Obesity, Physical Activity, Diet
- Sleep and related disorders
- Dietary Effects on Health
- Diet and metabolism studies
- Phytoestrogen effects and research
- Orthopaedic implants and arthroplasty
- Cytokine Signaling Pathways and Interactions
- Advanced Fluorescence Microscopy Techniques
- Consumer Attitudes and Food Labeling
- Pancreatic function and diabetes
- Cell Image Analysis Techniques
- Nutrition and Health in Aging
- Olfactory and Sensory Function Studies
- Regulation of Appetite and Obesity
- IL-33, ST2, and ILC Pathways
- Bone Tissue Engineering Materials
- Diabetes and associated disorders
- Tissue Engineering and Regenerative Medicine
- Electrospun Nanofibers in Biomedical Applications
- Ovarian function and disorders
- Neural dynamics and brain function
- 3D Printing in Biomedical Research
University of Colorado Anschutz Medical Campus
2022-2025
Goethe University Frankfurt
2019
The University of Texas Health Science Center at Houston
2019
West Virginia University
2016-2018
West Virginia University Hospitals
2017
New York University
2015
Proponents for electronic cigarettes (E-cigs) claim that they are a safe alternative to tobacco-based cigarettes; however, little is known about the long-term effects of exposure E-cig vapor on vascular function. The purpose this study was determine cardiovascular consequences chronic exposure. Female mice (C57BL/6 background strain) were randomly assigned daily vapor, standard (3R4F reference) cigarette smoke, or filtered air ( n = 15/group). Respective whole body exposures consisted four...
The purpose of this study was to evaluate the feasibility and acceptability randomizing adults with overweight obesity (BMI 25-40 kg/m
Long-term (≥12 months) randomized trials evaluating the efficacy of intermittent fasting (IMF) as a dietary weight loss strategy are limited. Furthermore, no studies have compared IMF versus daily caloric restriction (DCR) when both interventions provided in context guidelines-based behavioral program.
Abstract Background The objective of this secondary analysis was to examine the effect MVPA and time day that (i.e., morning vs. evening) is performed on long-term changes in body weight aerobic capacity. Methods Adults with overweight obesity ( n = 105) enrolled an 18-month behavioral loss intervention involving a reduced calorie diet supervised exercise program. Participants were encouraged increase their bouted accumulated bouts ≥ 10 min) 300 min/wk. Body weight, composition, capacity,...
We find no effect of follicle-stimulating hormone (FSH) on energy balance using a novel model in which rats are ovariectomized, subjected to gonadotropin-releasing antagonism, and systematically given back FSH by osmotic pump. However, tissue-specific effects adipose tissue liver were observed this study. These include unique transcriptomic signatures induced the stark reduction hepatic triglyceride accumulation.
To investigate the bone regenerative effect of polymer and collagen incorporation to synthetic graft materials.The ingrowth biphasic materials was tested in a rabbit calvaria defect model after chemical characterization: HA/TCP (25%/75%) with collagen, without (HA/TCP)/PLGA (85%/15%) (65%/35%) commercially available (50%/50%) (ReOss™, Intra-Lock International, Boca Raton, FL) used as control. After 4 8 weeks, retrieved samples were subjected histomorphometrical analysis.Histomorphometry...
Introduction The aim of this feasibility and proof-of-concept study was to examine the use a novel wearable device for automatic food intake detection capture full range free-living eating environments adults with overweight obesity. In paper, we document individuals that have not been thoroughly described previously in nutrition software as current practices rely on participant self-report methods limited environment options. Methods Data from 25 participants 116 total days (7 men, 18...
Rationale The precision of the doubly labeled water (DLW) method is determined by and accuracy isotopic measurements. Quality control (QC) procedures to mitigate sample variability require additional measurements if duplicates differ more than a factor instrument precision. We explored effect widening QC ranges on total daily energy expenditure (TDEE) using two‐point sampling method. Methods screened DLW data from 121 individuals for instances where samples were analyzed twice our existing...
Background Electronic cigarettes (E‐cigs) have exponentially increased in popularity and usage due to the perception that e‐cigs are safe, their usefulness as a cigarette‐smoking cessation tool, appeal of heavily marketed flavors. There is little known about long‐term effects E‐cig vapor exposure, particularly context vascular dysfunction. We hypothesize use decreased aortic function, increase stiffness. Methods Data were obtained from C57BL/6 female mice exposed 3R4F reference cigarette...
Nicotine and cigarette smoking is known to promote weight loss suppress appetite. Since becoming available in 2007, the use of electronic cigarettes (E‐cig) has increased dramatically US, however there are still very few studies that examine long‐term consequences e‐vapor, particularly context appetite regulation or management. The present study was devised compare effects smoke E‐cig vapor exposure on food intake, body weight, composition mice. We hypothesized E‐cigs would elicit similar...
Introduction Nicotine is a known central nervous system stimulant that increases heart rate and metabolism. E‐cigarettes (E‐cig) are new highly effective nicotine delivery device, include vast array of flavorings chemical by‐products likely to have deleterious consequences. Currently there very little about the long‐term effects E‐cig vapor exposure, particularly in context whole body We hypothesize metabolic cage activity will be increased mice chronically exposed vapor. Methods C57BL/6...
Introduction Traditional cigarette usage has been linked to a number of nefarious metabolic effects, including insulin resistance, however the effects electronic cigarettes (E‐cigs) are not currently known. Advertised as safe alternative for traditional tobacco cigarettes, long‐term studies investigating E‐cigs lacking. The purpose this study was gain better understanding possible consequences E‐cig usage. We hypothesize will induce resistance in mice. Methods C57BL/6 mice were divided...
Introduction Electronic cigarettes (E‐cigs) are gaining popularity in the United States and worldwide. Little is currently known about effects of chronic E‐cigarette exposure on cytokine expression throughout body. Methods C57BL/6 female mice were randomly assigned to cappuccino flavored E‐vapor (18 mg/ml nicotine, N=12) or filtered air (N=13) exposed groups. Animals 4 hours per day, 5 days week for 8 months. After major organs including lung, serum, gastrocnemius removed flash frozen...
Several studies have characterized the density of beta‐cell mass in rodents reporting greater amounts body and tail (which is most proximal to spleen) compared head pancreas (located curved duodenum). Whether or not obesity alters distributions within known. PURPOSE The objective this study was evaluate islet area a rat model metabolic syndrome. METHODS Obese (OZR, n=8) lean Zucker rats (LZR, were euthanized at 17‐weeks age. Pancreases harvested, sectioned into three regions (head, body,...