A5022744654- Hippo pathway signaling and YAP/TAZ
- Reproductive System and Pregnancy
- Cell Adhesion Molecules Research
- Genetics and Physical Performance
- Cellular Mechanics and Interactions
- Nuclear Receptors and Signaling
- Adipose Tissue and Metabolism
- Atherosclerosis and Cardiovascular Diseases
Xiangya Hospital Central South University
2025
Central South University
2025
Ruijin Hospital
2024
Shanghai Jiao Tong University
2020-2024
Renji Hospital
2020-2021
Jiangmen Central Hospital
2021
Poor endometrial receptivity results in embryo implantation failure. Acquisition of involves substantial structural alterations the cytoskeleton and plasma membrane epithelial cells, which facilitate adhesion. However, underlying molecular mechanism remains largely unknown. In this study, we identified that α-actinin-1 (ACTN1) was significantly downregulated mid-secretory phase endometrium compared with other phases; however, ACTN1 increased women recurrent failure (RIF). Ishikawa human...
Abstract Background: Alpha actinins (ACTNs) are major cytoskeletal proteins and exhibit many non-muscle functions. Emerging evidence have uncovered the regulatory role of ACTNs in tumorigenesis, however, expression pattern, biological functions, underlying mechanism ACTN1 hepatocellular carcinoma (HCC) remain largely unexplored. Methods: Immunohistochemical analysis a HCC tissue microarray (n = 157) was performed to determine pattern prognostic value HCC. In vitro loss-of-function study...
Abstract Background: Alpha actinins (ACTNs) are major cytoskeletal proteins and exhibit many non-muscle functions. Emerging evidence have uncovered the regulatory role of ACTNs in tumorigenesis, however, expression pattern, biological functions, underlying mechanism ACTN1 hepatocellular carcinoma (HCC) remain largely unexplored. Methods: Immunohistochemical analysis a HCC tissue microarray (n = 157) was performed to determine pattern prognostic value HCC. In vitro loss-of-function study...