A5036093388- Plant Gene Expression Analysis
- Microbial Metabolism and Applications
- Neurological Disease Mechanisms and Treatments
- Phytochemicals and Antioxidant Activities
- Photosynthetic Processes and Mechanisms
- Medicinal plant effects and applications
- Heat shock proteins research
- Cancer Mechanisms and Therapy
- Plant biochemistry and biosynthesis
- Drug Transport and Resistance Mechanisms
- Cancer-related Molecular Pathways
- Hidradenitis Suppurativa and Treatments
- Microscopic Colitis
- Phytochemistry and Bioactivity Studies
- Biochemical Analysis and Sensing Techniques
- Plant Stress Responses and Tolerance
- Phytoestrogen effects and research
- Advanced Breast Cancer Therapies
- PI3K/AKT/mTOR signaling in cancer
- Biochemical and biochemical processes
- Ginkgo biloba and Cashew Applications
- Chronic Myeloid Leukemia Treatments
- Inflammasome and immune disorders
- Cancer-related molecular mechanisms research
- Immune Cell Function and Interaction
Beijing Forestry University
2021-2025
State Forestry and Grassland Administration
2024-2025
Abstract Ovarian cancer (OV) poses a significant challenge in clinical settings due to its difficulty early diagnosis and treatment resistance. FOXP4, belonging the FOXP subfamily, plays pivotal role various biological processes including cancer, cell cycle regulation, embryonic development. However, specific importance of FOXP4 OV have remained unclear. Our research showed that is highly expressed tissues, with elevated levels correlating poor prognosis. We further explored FOXP4’s function...
Abstract Background Mei ( Prunus mume ) is the only woody plant in genus with a floral fragrance, but underlying mechanisms of aroma compound biosynthesis are unclear despite being matter considerable interest. Results The volatile contents petals two cultivars significantly different aromas, ‘Xiao Lve’ and ‘Xiangxue Gongfen’, were characterised by GC-MS at flowering periods, total 44 compounds detected. Among these, main substances forming typical P. identified as eugenol, cinnamyl acetate,...
Ginkgo (Ginkgo biloba L.) is a cherished relic among plants, commonly planted as street tree. However, it faces cultivation challenges due to escalating soil salinization and widespread snowmelt application. Therefore, this study used 4-year-old seedlings investigate how exogenous melatonin at varying concentrations affects seedling growth physiology under salinity stress. The results revealed that appropriate (0.02, 0.1 mmol·L−1) significantly mitigated leaf yellowing different NaCl stress...
Colon cancer ranks among the prevalent malignancies globally, and its proclivity for metastasis significantly contributes to adverse prognostic outcomes observed in patients. The epithelial-mesenchymal transition (EMT) represents a critical biological process through which tumor cells gain migratory invasive capabilities. Nilotinib is selective inhibitor of tyrosine kinases, commonly utilized treatment chronic myeloid leukemia. Prior investigations have demonstrated that derivative, N-12,...
Cyclin-dependent kinases 4 and 6 (CDK4/6) are central regulators of cell cycle progression frequently dysregulated in cancers, including breast cancer. While selective CDK4/6 inhibitors like Palbociclib, Ribociclib, Abemaciclib have shown clinical benefit hormone receptor-positive (HR+) cancer, their efficacy is often limited by resistance mechanisms dose-limiting toxicities. In this study, we developed LA-CB1, a novel derivative that induces degradation through the ubiquitin-proteasome...
Mei (Prunus mume Sieb. et Zucc.) is a rare woody species that flowers in winter, yet its large-scale propagation limited by the variable ability of cuttings to form adventitious roots (ARs). In this study, two cultivars were compared: P. ‘Xiangxue Gongfen’ (GF), which readily, and ‘Zhusha Wanzhaoshui’ (ZS), more recalcitrant. Detailed anatomical observations revealed following cutting, basal region expanded within 7 days, callus tissues had appeared 14 AR primordia emerged between 28 35...
Abstract Soil salinisation is an important factor limiting the cultivation and distribution of Prunus mume . Therefore, identifying regulation mechanism salt tolerance P. will promote its molecular breeding. In this study, garden tree species ‘Meiren’ was investigated, with a soil NaCl content (w/w) 0.3%. Photosynthetic gas exchange parameters, relative electrical conductivity, malondialdehyde, osmoregulation substances, antioxidant enzyme activity were measured in early (3d), middle (10d),...
The elucidation of resources pertaining to the
The present study aims to explore the genetic diversity of germplasm resources Chrysanthemum×morifolium (hereinafter, C.×morifolium) at molecular level and establish a fingerprint database C.×morifolium varieties. We employed 12 pairs primers with high levels polymorphism, clear bands, degrees reproducibility analyze SSR markers 91 materials 14 chrysanthemum- related materials. With regard constructing fingerprints tested materials, we chose 9 core primers. findings revealed that primer...
Abstract Previous research has highlighted a significant association between inflammatory proteins and the development progression of hidradenitis suppurativa (HS). Nevertheless, potential causative link these factors remains to be definitively established. To investigate genetic correlation HS, linkage disequilibrium score regression (LDSC) was employed. Mendelian randomization (MR) analysis, incorporating inverse variance weighted, MR‐Egger, weighted median methodologies, utilized evaluate...