Ilya A. Sedlov

ORCID: 0009-0004-1445-4924
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About
Contact & Profiles
Research Areas
  • 14-3-3 protein interactions
  • RNA and protein synthesis mechanisms
  • Lipid metabolism and biosynthesis
  • Biotin and Related Studies
  • Plant and Fungal Interactions Research
  • Microbial Natural Products and Biosynthesis
  • Plant Reproductive Biology
  • Advanced Proteomics Techniques and Applications
  • Plant Molecular Biology Research
  • Photosynthetic Processes and Mechanisms

A N Bach Institute of Biochemistry
2024-2025

Lomonosov Moscow State University
2025

Russian Academy of Sciences
2025

Moscow State University
2025

Institute of Bioorganic Chemistry
2023

Institute of Bioorganic Chemistry
2021-2023

Interaction of dimeric 14-3-3 proteins with phosphotargets regulates various physiological processes in plants, from flowering to transpiration and salt tolerance. Several genes express distinct "isoforms," particularly numerous but these are unevenly studied even model species. Here we systematically investigated twelve isoforms Arabidopsis thaliana. While all can homodimerize, four representing a supposedly more ancestral, epsilon phylogenetic group (iota, mu, omicron, epsilon), not their...

10.1111/tpj.70017 article EN The Plant Journal 2025-03-01

Molecular mechanisms underlying the green insect camouflage have puzzled researchers for over a century. Here, we isolated and identified water-soluble protein from integument of bush-cricket Tettigonia cantans . De novo sequencing cloning revealed severely fragmented form vitellogenins, ubiquitous multifunctional, but still largely enigmatic glycolipoproteins essential embryonic development lacking structural characterization. The distinctive color chromoprotein results binding remarkable...

10.1073/pnas.2502567122 article EN cc-by-nc-nd Proceedings of the National Academy of Sciences 2025-05-27

Abstract Interaction of dimeric 14-3-3 proteins with numerous phosphotargets regulates various physiological processes in plants, from flowering to transpiration and salt tolerance. Several genes express distinct ‘isoforms’, particularly but comparative studies all isoforms for a given organism have not been undertaken. Here we systematically investigated twelve the model plant Arabidopsis thaliana , uniformly capable homodimerization at high protein concentration. We unexpectedly discovered...

10.1101/2024.07.02.601760 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2024-07-03

10.31857/s0132342323040395 article EN Биоорганическая химия 2023-07-01

Abstract Recent evidence shows that small open reading frame (smORF; <100 codons)-encoded peptides (SEPs) containing transmembrane domains are preadapted to be progenitors of novel functional genes. A dozen such SEPs translated from long non-coding RNAs (lncRNAs) already functionally characterised in animals. However, plant lncRNA-smORF-coded not yet described. Here, we report detailed characterization a 41-aa peptide encoded by lncRNA-smORFs the moss Physcomitrium patens, which was named...

10.1101/2021.11.24.469821 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2021-11-25
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