A5100676493- Metabolomics and Mass Spectrometry Studies
- Peroxisome Proliferator-Activated Receptors
- Advanced Graph Theory Research
- Machine Learning in Bioinformatics
- Limits and Structures in Graph Theory
- Plant biochemistry and biosynthesis
- RNA Interference and Gene Delivery
- Metabolism and Genetic Disorders
- Cancer-related molecular mechanisms research
- Protein Structure and Dynamics
- Virus-based gene therapy research
- RNA modifications and cancer
- Advanced biosensing and bioanalysis techniques
- RNA and protein synthesis mechanisms
- Cancer Mechanisms and Therapy
- Urban Green Space and Health
- Cancer therapeutics and mechanisms
- Environmental Sustainability in Business
- Circular RNAs in diseases
- Neonatal Health and Biochemistry
- Vitamin C and Antioxidants Research
- Coding theory and cryptography
- Adipose Tissue and Metabolism
- Uterine Myomas and Treatments
- Cell death mechanisms and regulation
Hebei Medical University
2025
First Hospital of Shijiazhuang
2025
Ruijin Hospital
2025
Shanghai Jiao Tong University
2025
Huazhong Agricultural University
2023-2024
Sichuan Mianyang 404 Hospital
2024
Union Hospital
2024
Sichuan University
2024
Princeton University
2024
Qilu University of Technology
2024
Abstract Lactic acid, traditionally considered as a metabolic waste product arising from glycolysis, has undergone resurgence in scientific interest since the discovery of Warburg effect tumor cells. Numerous studies have proved that lactic acid could promote angiogenesis and impair function immune cells within microenvironments. Nevertheless, precise molecular mechanisms governing these biological functions remain inadequately understood. Recently, been found to induce posttranslational...
The past two decades have witnessed immense advances in quantum information technology (QIT), benefited by physics, chemistry, biology, and materials science engineering. It is intriguing to consider whether these diverse molecular supramolecular structures materials, partially inspired effects as observed sophisticated biological systems such light-harvesting complexes photosynthesis the magnetic compass of migratory birds, might play a role future QIT. If so, how? Herein, we review specify...
Endometriosis is a chronic inflammatory disorder characterized by presence of endometrial tissue outside the uterine cavity. Immunohistochemical analysis (IHC) revealed markedly elevated expression IL6ST in patients with ovarian endometriosis. Level methylation diminished endometriosis, whereas level mRNA RT-PCR. Cell Counting Kit-8, Transwell, Terminal deoxynucleotidyl transferase dUTP nick end labeling assays substantiated stromal cells stably transfected 3*FLAG-IL6ST plasmid exhibited...
Starting from the theoretical mechanism of impact financial agglomeration on regional green innovation efficiency, and using panel data 30 provinces in China 2009 to 2017, this study calculates a index efficiency applying principal component analysis slacks-based measure (SBM) super-efficiency. The then constructs static dynamic spatial Durbin models two different weight matrices empirically test spillover effect efficiency. results reveal significant positive correlation between China's...
Summary Objective This study sought to systematically compare the efficacy and mechanism of cyclodextrins as drug interventions in lipid metabolism diseases, potentially providing ideas for subsequent research directions clinical applications. Methods We used bibliometric method feature mining, applied VOSviewer software clustering analysis, content analysis objective descriptions accurate analysis. Results (1) collected more than 50 studies, which is basic database this study. (2) The...
With the rapid progress of technology, decision-making and behaviors artificial intelligence have begun to shift from external settings internal development. Intelligent agents gradually possess varying degrees adaptive, decision-making, behavioral abilities, their autonomous capabilities are continuously enhanced. For moral considerations, with has be regarded as a agent. Therefore, how traditional morality can play an role in intelligent technologies become problem that must faced. The...
The differences in clinical characteristics and treatment prognosis NSCLC patients harboring primary acquired BRAF mutations are still poorly understood. From Oct 2017 to Dec 2023, 10, 211 lung cancer at Shanghai Ruijin Hospital were reviewed. 88 15 BRAF-mutated resistant EGFR TKIs included the study. Primary preferentially occurred elderly (median age: 67 vs 61, p=0.015), males (53.4% 26.7%, p=0.056), former/current smokers (36.5% 6.7%, p=0.033), non-adenocarcinoma (11.4% 0%, P=0.351)...
High-density communities have proliferated globally during rapid urbanization. They are characterized by a high population density and limited per capita public spaces, making them susceptible to infectious disease risks. The impact of diseases in these communities, as evident the COVID-19 pandemic, underscores their vulnerabilities. Yet, research on prevention high-density areas remains limited. This study aims investigate relationship between built environment transmission urban with...
A new strategy for the construction of cationic lipid gene vectors non-viral delivery by simple and efficient multi-component Passerini reaction was provided, relevant structure–activity relationship studied.
Comparative metabolomics plays a crucial role in investigating gene function, exploring metabolite evolution, and accelerating crop genetic improvement. However, systematic platform for intra- cross-species comparison of metabolites is currently lacking. Here, we report the Plant Metabolome Database (PCMD; http://yanglab.hzau.edu.cn/PCMD), multilevel database based on predicted metabolic profiles 530 plant species. The PCMD serves as comparing characteristics at various levels, including...
Appropriate modification of LMW PEI not only enhanced gene transfection efficiency, but also provided a promising nucleic acid vaccine platform for anti-tumor immunotherapy.
Purpose: This study aims to investigate the predictive value of blood calcium in prognosis traumatic fracture. Methods: A retrospective experimental design was employed, 112 cases (52 non-fracture and 60 fracture) were randomly selected. The type fracture complies with WHO-recommended (2019) diagnostic criteria for osteoporosis combined pressure (BP) measured by OMRON's HEM-7136 model electronic monitor. Blood (Ca2+), phosphorus (P) values using Colorimetric Roche kits on a Roche/Hitachi...
Circular permutation in proteins is a phenomenon with significant implications the study of protein evolution and functionality. The detection such permutations traditionally reliant on structural alignment methods, which, while accurate, are computationally intensive require known three-dimensional structures. circular method based sequence dependencies may be faster, but it sacrifice some accuracy, especially for structures low similarity. To address these limitations, we introduce novel...
The planar Tur\'{a}n number of a graph $H$, denoted by $ex_{\mathcal{P}}(n,H)$, is the maximum edges in an $n$-vertex $H$-free graph. Recently, D. Ghosh, et al. initiated topic double stars and prove that $ex_{\mathcal{P}}(n,S_{2,5})\leq \frac{20}{7}n$. In this paper, we continue to study give sharp upper bound \frac{19}{7}n-\frac{18}{7}$ for all $n\geq 1$, with equality when $n=12$. This improves Ghosh's result.
The planar Tur$\acute{a}$n number of a graph $H$, denoted by $ex_{\mathcal{P}}(n,H)$, is the maximum edges in an $n$-vertex $H$-free graph. Recently, D. Ghosh, et al. initiated topic double stars and prove that $ex_{\mathcal{P}}(n,S_{2,5})\leq \frac{20}{7}n$. In this paper, we continue to study give sharp upper bound \frac{19}{7}n-\frac{18}{7}$ for all $n\geq 1$, with equality when $n=12$. This improves Ghosh's result.
Abstract Comparative metabolomics plays a crucial role in understanding gene function, exploring metabolite evolution, and improving crop genetic breeding. However, systematic platform for comparing intra- cross-species metabolites is currently lacking. In this study, we present the plant comparative metabolome database (PCMD; http://yanglab.hzau.edu.cn/PCMD ), comprehensive multi-level comparison encompassing metabolic profiling 530 plants. Remarkably, PCMD offers analysis, allowing...