Xing Fan

ORCID: 0009-0004-5639-0463
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About
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Research Areas
  • Maternal Mental Health During Pregnancy and Postpartum
  • Child and Adolescent Psychosocial and Emotional Development
  • Cervical Cancer and HPV Research
  • Hepatitis B Virus Studies
  • Attachment and Relationship Dynamics
  • Nonmelanoma Skin Cancer Studies
  • Anesthesia and Sedative Agents
  • Sympathectomy and Hyperhidrosis Treatments
  • Molecular Biology Techniques and Applications
  • Gut microbiota and health
  • Intensive Care Unit Cognitive Disorders
  • Gynecological conditions and treatments
  • Family Support in Illness
  • Cutaneous lymphoproliferative disorders research
  • Surgical Sutures and Adhesives
  • Intestinal and Peritoneal Adhesions
  • Cancer Mechanisms and Therapy
  • Porphyrin Metabolism and Disorders
  • Airway Management and Intubation Techniques
  • Photodynamic Therapy Research Studies
  • Adolescent and Pediatric Healthcare
  • Cutaneous Melanoma Detection and Management

Changsha Hospital for Maternal and Child Health Care
2016-2025

Hunan Normal University
2022-2025

Changsha Normal University
2025

First Affiliated Hospital of Anhui Medical University
2020-2023

Anhui Medical University
2020-2023

Hunan Provincial People's Hospital
2022

First Affiliated Hospital of GuangXi Medical University
2022

Guangxi Medical University
2022

High-risk human papillomavirus (HR-HPV) screening has increased colposcopy referrals, particularly for women with HR-HPV positivity but no intraepithelial lesion or malignancy (NILM) and those atypical squamous cells of undetermined significance (ASC-US). A fraction low-grade lesions (LSILs) is associated cervical neoplasia grade 2 worse (CIN2+) during diagnosis. This study evaluated the ability GYPC methylation (GYPCm ) to distinguish between <CIN2 CIN2 + in HPV-positive NILM, ASC-US, LSIL...

10.3389/fmed.2025.1575887 article EN cc-by Frontiers in Medicine 2025-04-17

Aim: To evaluate the clinical performance of PAX1 methylation (PAX1m) and cytology for patients with non-HPV16/18 high-risk HPV (hrHPV) infection. Methods: Cervical exfoliated cells from 387 outpatients hrHPV - positive were collected PAX1m assays. Results: The level increased severity histopathology. For cervical intraepithelial neoplasia (CIN)CIN2+/CIN3+, areas under curve both 0.87. specificity predictive value (PPV) greater than abnormal (CIN2+ specificity: 75.5 vs 24.8%; PPV: 38.8...

10.2217/fon-2023-0226 article EN cc-by-nc-nd Future Oncology 2023-06-08

Abstract Background The pandemic of coronavirus disease 2019 lastingly affects public mental health. Many studies have described symptoms anxiety and depression in pregnant women before the pandemic. However, limited study focuses on prevalence risk factors mood among first-trimester females their partners during China, which was aim study. Methods One hundred sixty-nine couples were enrolled. Edinburgh Postnatal Depression Scale, Patient Health Questionnaire-9, Generalized Anxiety Disorder...

10.1186/s12888-023-04621-2 article EN cc-by BMC Psychiatry 2023-03-03

Introduction Family functioning has been found to significantly impact each family member’s health mentally, physically, and socially. A number of the research focused on impaired in general, but limited studies explore vulnerable period, early pregnancy. Therefore, study aimed investigate characteristics related factors Chinese females partners during Methods The cross-sectional enrolled 226 pregnant women 166 partners. Assessment tools included McMaster Device (FAD), Edinburgh Postnatal...

10.3389/fpsyg.2023.1102796 article EN cc-by Frontiers in Psychology 2023-02-15

Primary screening for high-risk human papillomavirus (hrHPV) with cytological triage women non-16/18 hrHPV-positive status has become popular in China. However, cytology relies on the subjective judgment of pathologists, leading to inconsistent clinical performance. A total 657 aged 25–64 years were enrolled this cross-sectional study. All participants underwent colposcopic biopsy after triage, residual specimens undergoing DNA methylation testing. CIN2+ and CIN3+ sensitivity specificity...

10.1186/s12885-024-13126-4 article EN cc-by-nc-nd BMC Cancer 2024-11-04

Abstract Background Keratoacanthoma (KA) is a special kind of tumor, which regarded as variant squamous cell carcinoma (SCC) in some academic disciplines. But differentiating KA from SCC remains diagnostic challenge. The noninvasive techniques dermoscopy and reflectance confocal microscopy (RCM) can provide new insights for diagnosis. Objective To observe the characteristics under (RCM), order to gain experience reference clinicians facilitate earlier Methods We collected two cases KA, were...

10.1111/srt.12975 article EN Skin Research and Technology 2020-10-24

Objective To investigate the effect of microRNA-204 (miR-204) on invasion cervical cancer Hela cells and its underlying mechanism. Methods Hela were assigned to 4 groups. The negative control group was added with random microRNA sequences. miR-204 mimetic (agomir-204) inhibitor (antagomir-204) group. A blank not processed. At 72 h, retrieved. Fluorescence quantitative real-time PCR used detect levels in each expression Ezrin (EZR) protein detected by immunoblotting. targeting sequence...

10.3760/cma.j.issn.1674-1927.2016.06.005 article EN Chin J Biomed Eng 2016-12-15

Abstract Background: The pandemic of coronavirus disease 2019 lastingly affects public mental health. Many studies have described symptoms anxiety and depression in pregnant women during the pandemic. However, limited study focuses on prevalence risk factors mood among females their partners early pregnancy post-pandemic era China, which was aim could promote clinical attention suggest possible directions for intervention. Methods: One hundred sixty-nine first-trimester couples were...

10.21203/rs.3.rs-2279007/v1 preprint EN cc-by Research Square (Research Square) 2022-11-23
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