A5088144921- Autophagy in Disease and Therapy
- Mosquito-borne diseases and control
- HIV Research and Treatment
- Sirtuins and Resveratrol in Medicine
- Prostate Cancer Diagnosis and Treatment
- Brain Metastases and Treatment
- Heart Failure Treatment and Management
- Seismic Imaging and Inversion Techniques
- Blood Pressure and Hypertension Studies
- Global Cancer Incidence and Screening
- Hydraulic Fracturing and Reservoir Analysis
- interferon and immune responses
- Erythropoietin and Anemia Treatment
- Inflammasome and immune disorders
- Drilling and Well Engineering
- Climate Change and Health Impacts
- Prostate Cancer Treatment and Research
- Advances in Oncology and Radiotherapy
- Calcium signaling and nucleotide metabolism
- Radiomics and Machine Learning in Medical Imaging
- Chronic Kidney Disease and Diabetes
- Viral Infections and Vectors
- Global Public Health Policies and Epidemiology
Guiyang Medical University
2022-2024
Northeast Petroleum University
2022
Abstract Background Prostate cancer (PCa) is the second most common among men worldwide. This study uses data from 2021 Global Burden of Disease (GBD) to estimate global burden prostate 1990 2021. Methods We analyzed incidence, mortality, and disability-adjusted life years (DALYs) globally Based on Sociodemographic Index (SDI), we used estimated annual percentage change (EAPC) Age-Period-Cohort model compare disease across different age groups regions with varying levels development....
Abstract The global incidence of dengue fever has gradually increased in recent years, posing a serious threat to human health. In the absence specific anti-dengue drugs, understanding interaction Dengue virus (DENV) with host is essential for development effective therapeutic measures. Autophagy often activated during DENV infection promote viral replication, but mechanism how DENV's own proteins induce autophagy not been clarified. this study, we first preliminarily identified DENV-2 NS1...
Background The global burden of chronic kidney diseases related heart failure (CKD-related HF) has yet to be reported. study aims analyze the CKD-related HF. Methods Utilizing data from Global Burden Disease Study 2021, we delineated prevalence and years lived with disability (YLDs) HF at global, regional, national levels, alongside its age sex distributions, as well temporal trends. Furthermore, conducted transnational inequality analysis frontier analysis. Additionally, analyzed diverse...
Background: Low Physical Activity (LPA) is a recognized risk factor for Chronic Kidney Disease (CKD). However, there currently lack of research reports addressing the global burden CKD attributable to LPA. Methods: We systematically described LPA globally, regionally, and nationally using data from Global Burden Study 2021. examined distribution by age, sex, time trends. Furthermore, we conducted analyses on cross-national inequalities frontier analysis. Additionally, analyzed among...
Dengue virus type 2 (DENV-2) was used to infect primary human umbilical vein endothelial cells (HUVECs) examine autophagy induced by activation of the adenosine monophosphate-activated protein kinase (AMPK)/extracellular signal-regulated (ERK)/mammalian target rapamycin (mTOR) signaling pathway following tripartite motif-containing 22 (TRIM22)-mediated DENV-2 infection further reveal underlying pathogenic mechanism infection.Quantitative real-time polymerase chain reaction (qRT-PCR) screen...
Abstract Renal anemia has inflicted a certain degree of loss on global health. However, there are no systematically analyses the burden renal anemia. We analyzed prevalence and years lived with disability (YLDs) from 1990 to 2021. Based Socio-Demographic Index (SDI), combined cross-national inequality analysis, frontier analysis age-period-cohort (APC) model YLDs differences between different aspects were compared. Since 1990, in 2021 have shown an upward trend. In countries medium low...
Abstract The bedding layers in shale reservoirs are highly developed with numerous joints. In the hydraulic fracturing process, propagation of fractures during formation significantly affects efficient development reservoirs. this study, we employed pulsating cyclic loading technique to develop a model interaction between and layer; addition, used numerical optimization method for zero-thickness cohesive element compare fracture layer behavior under static loading. We studied at different...
Abstract Background: Dengue virus type 2 (DENV-2) was used to infect primary human umbilical vein endothelial cells (HUVECs) examine autophagy induced by activation of the adenosine monophosphate-activated protein kinase (AMPK)/extracellular signal-regulated (ERK)/mammalian target rapamycin (mTOR) signaling pathway following tripartite motif-containing 22 (TRIM22)-mediated DENV-2 infection further reveal underlying pathogenic mechanism infection. Methods: Quantitative real-time polymerase...
Abstract Background Dengue virus type 2 (DENV-2) was used to infect primary human umbilical vein endothelial cells (HUVECs) examine autophagy induced by activation of the adenosine monophosphate-activated protein kinase (AMPK)/extracellular signal-regulated (ERK)/mammalian target rapamycin (mTOR) signaling pathway following tripartite motif-containing 22 (TRIM22)-mediated DENV-2 infection further reveal underlying pathogenic mechanism infection. Methods Quantitative real-time polymerase...