Qi‐Long Zhang

ORCID: 0000-0002-9621-4016
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Molecular Sensors and Ion Detection
  • Luminescence and Fluorescent Materials
  • Oceanographic and Atmospheric Processes
  • Climate variability and models
  • Marine and coastal ecosystems
  • Sulfur Compounds in Biology
  • Supramolecular Chemistry and Complexes
  • Ocean Waves and Remote Sensing
  • Metal complexes synthesis and properties
  • Magnetism in coordination complexes
  • Nanoplatforms for cancer theranostics
  • Advanced biosensing and bioanalysis techniques
  • Adipose Tissue and Metabolism
  • Oxidative Organic Chemistry Reactions
  • Environmental Changes in China
  • Analytical Chemistry and Chromatography
  • Synthesis and Characterization of Heterocyclic Compounds
  • Photochromic and Fluorescence Chemistry
  • Axial and Atropisomeric Chirality Synthesis
  • Geological and Geophysical Studies
  • Porphyrin and Phthalocyanine Chemistry
  • Metal-Catalyzed Oxygenation Mechanisms
  • Traditional Chinese Medicine Analysis

Guiyang Medical University
2016-2025

Shanghai University of Sport
2024

University of Jinan
2016-2023

Yulin University
2021

Anhui Medical University
2021

Guiyang University
2018-2020

Guizhou University
2007-2019

Chinese Academy of Sciences
2001-2018

Institute of Oceanology
2002-2018

Qingdao National Laboratory for Marine Science and Technology
2018

A tetraphenylethylene-functionalized salicylaldehyde Schiff-base fluorescent probe (<bold>TPE-An-Py</bold>) with aggregation-induced enhanced emission (AIEE) characteristics exhibited high sensitivity towards copper(<sc>ii</sc>) ions in aqueous media a “turn-off” fluorescence mechanism; limit of detection is 2.36 × 10<sup>−7</sup>mol L<sup>−1</sup>.

10.1039/c9qm00759h article EN Materials Chemistry Frontiers 2020-01-01

An aniline-functionalized naphthalene dialdehyde Schiff base fluorescent probe L with aggregation-induced enhanced emission (AIEE) characteristics was synthesized via a simple one-step condensation reaction and exhibited excellent sensitivity selectivity towards copper(II) ions in aqueous media fluorescence “ turn-off ” phenomenon. The detection limit of the is 1.64 × 10−8 mol·L−1. Furthermore, according to results UV-vis/fluorescence titrations, Job’s plot method 1H-NMR 1:2 stoichiometry...

10.3390/molecules26051233 article EN cc-by Molecules 2021-02-25

Purpose: This study aimed to investigate the molecular mechanisms of Compound Sidaxue (SX), a prescription Chinese Miao medicine, in treating rheumatoid arthritis (RA) using network pharmacology and vivo experimental approaches. Methods: Network was adopted detect active components four Traditional herbal medicine (TCM) SX, key targets signaling pathways treatment RA were predicted, screened for docking. The predicted validated bovine type II collagen incomplete Freund's adjuvant...

10.2147/dddt.s330947 article EN cc-by-nc Drug Design Development and Therapy 2022-02-01

Multidrug-resistant (MDR) bacteria pose serious threats to public health due the lack of effective and biocompatible drugs kill MDR bacteria. Photodynamic antibacterial therapy has been widely studied its low induction resistance. However, photosensitizers that can efficiently generate reactive oxygen species (ROS) through both type I II mechanisms have capability multiple modes action are rarely reported. Addressing this issue, we developed a near-infrared-emitting triphenylamine indole...

10.1021/acsami.4c05202 article EN ACS Applied Materials & Interfaces 2024-06-07

Cancer cells are characterized by high viscosity, low pH and levels of reactive oxygen species. viscosity key indicators which can respond to the microenvironment cancer...

10.1039/d4tb02711f article EN Journal of Materials Chemistry B 2025-01-01

The coordination between a ligand and metal is spontaneous uncontrollable process. In this Article, we successfully observe the formation of in triphenylamine-functionalized salicylaldehyde Schiff base with copper(II) ion. TPA-Py first reacts Cu2+ stepwise process to afford dynamic complex TPA-Py@Cu2+ ([ligand]:[Cu2+] = 1:1), which further an extra ion 2TPA-Py@4Cu2+ following (or cumulative) stability constants: K1 4.0694 × 103 K2 1.0761 106, respectively. entire can be visualized, mode...

10.1021/acs.inorgchem.1c00523 article EN Inorganic Chemistry 2021-06-07

This work provides a naphthaldehyde-based Schiff base with reversible multiple stimuli-responsive behaviour of AIEE mechanochromic luminescence, which functions as sensitive chemosensor for Cu 2+ ions.

10.1039/d2qm00542e article EN cc-by Materials Chemistry Frontiers 2022-01-01

Co/Fe bimetallic spherical nanomaterials were synthesized by hydrothermal method as an efficient heterogeneous catalyst, which can catalyze the selective oxidation of benzyl alcohol to benzaldehyde O2, thereby replacing stoichiometric reagents such chromate and manganese oxide. CoFe2O4 has good activity selectivity for alcohol. The catalyst catalyzes preparation formaldehyde from oxide O2 at 150 °C, with a conversion rate 95.3% yield 96.7%. Furthermore, is recycled 5 consecutive uses without...

10.1016/j.catcom.2023.106757 article EN cc-by Catalysis Communications 2023-09-04

Photodynamic therapy (PDT) brings new hope for the treatment of breast cancer due to few side effects and highly effective cell killing; however, low bioavailability traditional photosensitizers (PSs) their dependence on oxygen severely limits application. Aggregation-induced emission (AIE) PSs can dramatically facilitate photosensitization effect, which have positive impacts tumor PDT. To-date, most AIE lack targeting capability possess poor delivery, resulting in use large quantities that...

10.1016/j.ajps.2024.100967 article EN cc-by-nc-nd Asian Journal of Pharmaceutical Sciences 2024-09-21

Organic reaction is a powerful and versatile tool for the creation of various new substrates materials. However, there have been few reports direct fabrication organic particles by reactions. Herein, we report that water as co-solvent can efficiently switch [2 + 2] macrocycle (3) to [1 1] (4) in Schiff-base from same precursors at room temperature. Unexpectedly, series tunable micro/nanoparticles, including solid microspheres, core–shell spheres, vesicles, could be directly precipitated...

10.1021/acsnano.8b09478 article EN ACS Nano 2019-01-31

A novel turn-on fluorescence probe L has been designed that exhibits high selectivity and sensitivity with a detection limit of 9.53 × 10−8 mol/L for the quantification Zn2+. 1H-NMR spectroscopy single crystal X-ray diffraction analysis revealed unsymmetrical nature structure Schiff base L. An emission titration experiment in presence different molar fractions Zn2+ was used to perform Job’s plot analysis. The results showed stoichiometric ratio complex formed by 1:1. Moreover, molecular...

10.3390/molecules26133825 article EN cc-by Molecules 2021-06-23

Antibacterial hydrogels, as novel antibacterial materials with inherent or exogenous activity, can be used for local use, controlled drug release, stimulus-responsive activation, synergistic therapy, realizing its translational applications in different medical fields.

10.1039/d3tc02166a article EN Journal of Materials Chemistry C 2023-01-01

Abstract The global incidence of dengue fever has gradually increased in recent years, posing a serious threat to human health. In the absence specific anti-dengue drugs, understanding interaction Dengue virus (DENV) with host is essential for development effective therapeutic measures. Autophagy often activated during DENV infection promote viral replication, but mechanism how DENV's own proteins induce autophagy not been clarified. this study, we first preliminarily identified DENV-2 NS1...

10.1186/s12985-023-02166-0 article EN cc-by Virology Journal 2023-10-11

Bacterial infections typically invade the living tissue of wounds, thereby aggravating inflammatory response, delaying wound healing, or causing further complications. In this paper, antibacterial hydrogel (PNVBA) with antifreezing and antidrying properties was prepared by a two-step method using N-isopropylacrylamide (NIPAM), 1-butyl-3-vinylimidazolium bromide (VBIMBr), 3-acrylamidophenylboronic acid (AAPBA). PNVBA hydrogels exhibited high adsorption capacity 280 mg·g–1 for bovine serum...

10.1021/acs.biomac.3c01040 article EN Biomacromolecules 2023-12-27

The adipokine chemerin contributes to exercise-induced improvements in glucose and lipid metabolism; however, the underlying mechanism remains unclear. We aimed confirm impact of reduced expression on improvement glycolipid metabolism male diabetic (DM) mice through exogenous administration. Furthermore, involved changes muscle mitochondria function mediated by androgen/androgen receptor (AR) was explored generating adipose-specific global knockout (adipo-chemerin

10.1152/ajpendo.00104.2023 article EN AJP Endocrinology and Metabolism 2024-05-22
Coming Soon ...