A5033487568- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Venous Thromboembolism Diagnosis and Management
- Acute Myocardial Infarction Research
- Cerebrovascular and Carotid Artery Diseases
- Cardiac Valve Diseases and Treatments
- Cardiovascular Function and Risk Factors
- Acute Ischemic Stroke Management
- Hepatocellular Carcinoma Treatment and Prognosis
- Atrial Fibrillation Management and Outcomes
- Aortic aneurysm repair treatments
- Mechanical Circulatory Support Devices
- Peripheral Artery Disease Management
- Vascular Anomalies and Treatments
- Advanced MRI Techniques and Applications
- Diagnosis and Treatment of Venous Diseases
- Renal and Vascular Pathologies
- Healthcare Systems and Challenges
- Cardiac Arrhythmias and Treatments
- Oropharyngeal Anatomy and Pathologies
- Cardiac and Coronary Surgery Techniques
- Liver physiology and pathology
- Organ Transplantation Techniques and Outcomes
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiovascular Health and Disease Prevention
Beaumont Hospital, Royal Oak
1999-2024
Beaumont Health
2018-2021
Oakland University
2018-2019
Beaumont Hospital, Troy
2000
University of Minnesota
1994
Twin Cities Orthopedics
1994
University of Minnesota System
1993
Gottsegen National Cardiovascular Center
1993
Hemodynamically unstable high-risk, or massive, pulmonary embolism (PE) has a reported in-hospital mortality of over 25%. Systemic thrombolysis is the guideline-recommended treatment despite limited evidence. The FLAME study (FlowTriever for Acute Massive PE) was designed to generate evidence interventional treatments in high-risk PE.
Although the salutary effects of reperfusion in patients with left ventricular infarction are well documented, benefits acute right less clear.
Hepatic artery collaterals in 40 patients who had hepatic occlusion following peripheral or central embolization, surgical ligation, intra-arterial chemotherapy, intimal injury from catheterization were studied. The classified as intrahepatic extrahepatic collaterals. Intrahepatic arterial develop the portal triads and subcapsular area between lobes of liver. Extrahepatic ligaments that suspend liver peritoneal cavity through structures are closely attached to A simplified angiographic...
No-flow has been reported after 10-15% of percutaneous interventions on degenerated saphenous vein grafts. In this prospective study 36 graft lesions (32 patients), no-flow (TIMI flow < 3 in the absence a significant lesion or dissection) occurred 15/36 (42%) lesions. A total 32 episodes angioscopy (n = 14), extraction atherectomy 10), balloon angioplasty 2) stent implantation 6). Intragraft nitroglycerin (100-300 micrograms) alone resulted no improvement TIMI setting no-reflow 1.2 +/- 0.6...
Ivalon particles were used for 80 hepatic artery embolizations in 50 patients who had either primary or metastatic neoplasms. Ten died within 1-5 months and the remaining 40 still alive. The post-hepatic embolization syndrome was identical to that following Gelfoam embolization. Follow-up angiography 20 revealed tumor response 17 patients. easier use caused more peripheral persistent occlusion than Gelfoam. results suggest safe feasible
Ultrasound-accelerated thrombolysis (USAT) is advocated in pulmonary embolism (PE) based on the hypothesis that adjunctive ultrasound provides superior clinical efficacy compared to standard catheter-directed (CDT). This retrospective study was designed compare outcomes between two modalities. We analyzed patients with computed tomography-diagnosed PE at our institution treated either USAT or CDT. Efficacy parameters assessed included invasive artery systolic pressure (PASP; pre- and 24...
Background— Although proximal right coronary artery (RCA) occlusion is the culprit commonly responsible for acute ventricular (RV) infarction (RVI), severity of RV dysfunction ranges broadly. This study was designed to delineate patterns compromise that determine magnitude ischemic dysfunction. Methods and Results— In 125 patients with inferior myocardial undergoing emergency angiography, infarct lesion identified, branch flow assessed (TIMI flows frame counts), individual patient perfusion...
Twenty-four patients with hepatocellular carcinoma or cholangiocarcinoma were treated hepatic artery infusion (HAI) of chemotherapeutic agents (14 patients) embolization (HAE) (11 patients). One patient had a combination the two treatments. Ten 14 (71%) who underwent HAI demonstrated partial remission. The median survival time was 12.3 months. Six 9 (67%) HAE and for whom follow-up available responded to treatment. those 17.4
Background The purpose of this study was to assess serial changes in coronary blood flow velocity before and after Rotablator atherectomy adjunctive percutaneous transluminal angioplasty (PTCA). Since results luminal enlargement by plaque pulverization distal embolization, improvement could be attenuated despite enlargement. Methods Results Intracoronary Doppler measurements were obtained with a Flowire. Basal average peak (bAPV), hyperemic APV (hAPV), diastolic/systolic ratio (DSVR),...
The BARASTER registry was formed to evaluate the initial success and long-term results of rotational atherectomy in management in-stent restenosis. Rotational used 197 cases restenosis: 46 with stand-alone or at most 1 atmosphere balloon inflation (Rota strategy), 151 adjunctive angioplasty <1 (Combination strategy). These were compared 107 episodes restenosis treated alone. In this observational study, use Combination therapy associated a slightly higher rate (95% vs. 87% Rota strategy 89%...
Abstract Objectives The purpose of the present study is to evaluate safety and efficacy “low‐dose” systemic thrombolytic therapy (TT) for treatment patients with intermediate‐high risk submassive pulmonary embolism (PE). Background TT increasingly utilized in acute PE. Strategies include catheter‐directed administration as well traditional IV therapy. Regardless route, most studies document attendant significant bleeding complication rates expected from induction a lytic state. To mitigate...
Abstract The purpose of this study was to compare a newly developed Doppler guide wire in the measurement coronary blood flow velocity (CBFV) and reserve (CFR) when compared previously extensively validated catheter. Sequential measurements signals from catheter were obtained response graded doses intracoronary adenosine left circumflex 10 anesthetized dogs. signal recorded on standard physiologic chart recorder; that both recorder commercially available spectral analysis recording system....
Some patients with severe carotid stenosis have anatomical or clinical comorbidities that place them at high risk for endarterectomy (CEA). The early and late outcomes after artery stenting (CAS) were evaluated in CEA.Between 2002 2009, 186 enrolled a high-risk CAS institutional registry. primary outcome was major adverse cardiac cerberovascular events (MACCEs) 30 days, including death, stroke, myocardial infarction. Secondary technical, procedural, success; nonstroke neurological events;...
Intra-arterial infusion of chemotherapeutic agents (CDDP alone or combined with DTIC) was used to treat recurrent melanoma in 22 patients. In 17 cases, sequential arteriograms were obtained before and after monitor the procedure. Pre-treatment angiograms usually demonstrated rounded nodules a homogeneous, hypervascular stain. 3 patients, additional deep-seated lesions which not palpable clinically detected by angiography. Arteriograms those patients who responded chemotherapy revealed...
ABSTRACT Recent advances in therapy and the promulgation of multidisciplinary pulmonary embolism teams (PERTs) show great promise to improve management outcomes acute (PE). However, absence randomized evidence lack consensus leads tremendous variations treatment compromises wide implementation new innovations. Moreover, changing landscape healthcare, where quality, cost, accountability are increasingly relevant, dictates that a broad spectrum care must be routinely monitored fully capture...
Venous thromboembolism from a “thrombotic storm”–like syndrome is major cause of morbidity and mortality in patients with active or “recovered” COVID-19. Patients should be risk-stratified, optimally by pulmonary embolism (PE) response team (PERT), considered for escalation care if found intermediate high-risk PE. We present series COVID-19-associated PE thrombotic storm D-dimer >10 000 ng/mL who underwent successful mechanical thrombectomy to All had immediate improvement hemodynamics...