A5087366747- Advanced biosensing and bioanalysis techniques
- Advanced Nanomaterials in Catalysis
- MXene and MAX Phase Materials
- Gold and Silver Nanoparticles Synthesis and Applications
- Electrochemical sensors and biosensors
- Nanocluster Synthesis and Applications
- Endoplasmic Reticulum Stress and Disease
- RNA and protein synthesis mechanisms
- Bacterial Genetics and Biotechnology
- Graphene and Nanomaterials Applications
- Bacteriophages and microbial interactions
- Tuberculosis Research and Epidemiology
- Metal-Organic Frameworks: Synthesis and Applications
- CRISPR and Genetic Engineering
- Heat shock proteins research
- Molecular Sensors and Ion Detection
- Xenotransplantation and immune response
Banaras Hindu University
2023-2025
Indian Institute of Technology BHU
2023-2024
Indian Institute of Chemical Biology
2018-2019
Academy of Scientific and Innovative Research
2019
University of Hyderabad
2017
Bone is a dynamic tissue that serves several purposes in the human body, including storing calcium, forming blood cells, and protecting supporting body's organs. Alkaline phosphatase (ALP) secreted into circulation by osteoblasts, cells responsible for making bone. It attaches to surface of osteoblast or matrix vesicles. Accordingly, ALP present serum popular biomarker evaluation bone disease other disorders clinical evaluations. In this study, composite probe made bioactive glass (BG)...
The superoxide anion radical (O2•–) is produced as a byproduct of regular cellular respiration and plays crucial roles in numerous functions, including homeostasis, cell proliferation, migration, apoptosis. However, when its regulation disrupted, it linked to various illnesses, cancer, autoimmune diseases, cardiovascular neurodegenerative etc. Hence, developing precise detection methods for O2•– measurement has recently drawn much scientific attention. Herein, we report the fabrication...
In recent years, an increase in the number of chronic kidney disease (CKD) cases has led to a global health burden majorly affecting underdeveloped and developing nations. A key biomarker for assessing kidneys' normal functioning is creatinine, which filtered out from blood by kidney. Thus, timely specific detection creatinine becomes necessary diagnosis subsequent treatment CKD. Hence, this study, we have tried develop field-deployable, software-integrated immunosensor serum sample. The was...
Biomimetic synthesis of multifunctional fluorescent gold nanoclusters (Au NCs) is great demand because their ever-increasing applications. In this study, we have used self-assembled bovine serum albumin (BSA) amyloid-like nanofibers as the bioinspired scaffold for Au NCs. The amyloid fibril stabilized nanocluster (Fib-Au NC) has been found to appreciable enhancement fluorescence emission and a large 25 nm red shift in its maxima when compared monomeric protein counterpart (BSA-Au NC)....
Au–Ag bimetallic nanoclusters with tunable NIR fluorescence have found applications in sensing toxic lead ions <italic>in vitro</italic> and inside cells.
Virulent Mycobacterium tuberculosis (MTB) strains cause cell death of macrophages (Mϕ) inside TB granuloma using a mechanism which is not well understood. Many bacterial systems utilize toxins to induce host damage, occurs along with immune evasion. These often use chameleon sequences generate an environment-sensitive conformational switch, facilitating the process infection. The presence yet known for MTB. Here, we show that MTB-secreted immunogenic MPT63 protein undergoes switch from...