A5007222792- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Venous Thromboembolism Diagnosis and Management
- Cardiac pacing and defibrillation studies
- Abdominal Trauma and Injuries
- Cardiovascular Effects of Exercise
- Pelvic and Acetabular Injuries
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Reproductive tract infections research
- Pericarditis and Cardiac Tamponade
- Cardiovascular Disease and Adiposity
- Inhalation and Respiratory Drug Delivery
- Respiratory Support and Mechanisms
- Intestinal and Peritoneal Adhesions
- Diabetes Management and Education
- Cardiac Ischemia and Reperfusion
- Airway Management and Intubation Techniques
- Amoebic Infections and Treatments
- Wound Healing and Treatments
- Diagnosis and Treatment of Venous Diseases
- Minimally Invasive Surgical Techniques
- Urological Disorders and Treatments
- Dysphagia Assessment and Management
- Cardiovascular and Diving-Related Complications
St. Josefs Hospital
2020-2025
Bernhard Nocht Institute for Tropical Medicine
2023
Garmisch-Partenkirchen Medical Center
1989-2023
Lipidomix (Germany)
2013-2014
Ludwig-Maximilians-Universität München
1981-2010
Klinik für Psychosomatik
2006
Differences in immune response between men and women may influence the outcome of infectious diseases. Intestinal infection with Entamoeba histolytica leads to hepatic amebiasis, which is more common males. Previously, we reported that innate cells contribute liver damage males murine model for amebiasis. Here, focused on influences sex androgens neutrophils particular. Infection associated neutrophil accumulation was higher male than female mice further increased after testosterone...
Age is a major risk factor for development of atrial fibrillation (AF) and associated with increased recurrence rates in the setting rhythm control. Current data tend to support catheter ablation elderly patients, but uncertainties exist regarding efficacy safety patients.
Patients with obesity are at higher risk of developing atrial fibrillation (AF) and benefit from radiofrequency ablation. Potentially, cryoballoon ablation (CBA) may be equally effective safe in such patients.We conducted a prospective, single-center study to investigate whether CBA for pulmonary vein isolation is as obese patients it non-obese controls. Primary efficacy endpoint was recurrence AF, flutter or tachycardia after 90-day blanking period. Safety endpoints were death, stroke...
Electrical cardioversion (ECV) is highly effective in restoring sinus rhythm patients with atrial fibrillation (AF), but it does not influence long-term control. Remote ischemic preconditioning (RIPC) has demonstrated various cardioprotective effects. Combining ECV RIPC could provide a promising approach to minimizing AF recurrences after successful ECV. This prospective, randomized, single-blinded, single-centre study investigated the impact of on early recurrence following (defined as ≥ 30...
Abstract Background Cardiovascular diseases and increasing age are risk factors for the occurrence of atrial fibrillation (AF). Current data provide evidence a prognostic benefit from rhythm control strategy, which is most effectively achieved by catheter ablation. High comorbidity burden may impact on procedural efficacy incidence cardiovascular events following pulmonary vein isolation (PVI). Methods Consecutive AF patients who underwent first-time PVI with cryoballoon (cryoPVI) were...
(1) Background: Cryoballoon pulmonary vein isolation (cryoPVI) is established for symptomatic paroxysmal atrial fibrillation (AF) treatment, but its value in persistent AF less clear. In particular, limited data are available on efficacy elderly patients (≥75 years) with AF. Age an important modifier of progression and represents a risk-factor recurrence. (2) Methods: Prospective, single-center observational study to evaluate the impact age safety cryoPVI patients. Primary endpoint was...
Abstract Background Age is a major risk factor for development of atrial fibrillation (AF) and associated with increased recurrence rates in the setting rhythm control. Current data tend to support catheter ablation elderly patients, but it remains unclear whether there an age limit potential benefits justify potentially complication rate elderly. Objective To prospectively analyze impact on efficacy safety cryoballoon (CBA). Methods ; We analyzed consecutive patients who underwent CBA...
Background Heart failure with reduced ejection fraction is associated potentially deleterious imbalance of the cardiac autonomic nervous system. Sacubitril/valsartan (angiotensin receptor‐neprilysin inhibitor [ARNI]) reduces cardiovascular mortality and hospitalization for heart fraction. Whether ARNI affects system has not been studied. Methods Results This investigator‐initiated, prospective, single‐center cohort study compared rate (HR) variability, HR, deceleration capacity, periodic...
In the light of an increasing prevalence atrial fibrillation (AF) and growing evidence for superiority early invasive rhythm control, demand ablation therapy is rising. Accordingly, centres will have to maximize their capacity by either adding electrophysiology laboratory resources or optimizing process management. order optimize management, we applied "Lean Six Sigma" method a single center. We compared procedural parameters, acute efficacy safety cryoballoon pulmonary vein isolation...
Drug Prescribing for Patients with Chronic Kidney Disease in General Practice: a Cross-Sectional Study
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Abstract Background While a gender-specific influence has been demonstrated for many cardiovascular interventions, no prospective data is yet available cryoballoon pulmonary vein isolation (CryoPVI). Methods We prospectively analyzed consecutive AF patients who underwent first CryoPVI in single-center cohort between 2018 and 2023. stratified regarding gender into two groups. was performed standardized procedure. Foollow-up at 3, 6, 12, 18, 24 36 months after CryoPVI. Efficacy endpoint the...
Abstract Background According to current guidelines, the occurrence of atrial fibrillation (AF) recurrence within first 90 days after pulmonary vein isolation (PVI) should not indicate re-do procedures. Accordingly, a 90-day blanking period is usually accepted. However, data suggests that early arrhythmia relapses during have an impact on efficacy. The optimal for indicating re-ablation therefore remains unclear. Methods We prospectively analyzed consecutive AF patients who underwent...
Abstract Background Cryoballloon pulmonary vein isolation (CryoPVI) is well established for atrial fibrillation (AF) ablation. Nevertheless, it still important to identify possible periprocedural factors influencing its efficacy. With difficult anatomical conditions currently unclear whether the number of cryoballoon applications needed achieve complete has an impact on long-term effectiveness CryoPVI. Methods We prospectively analyzed AF patients who underwent first-time CryoPVI in a single...
Fragestellung: Die Arzthelferin stellt für den Patienten die erste Anlaufstelle dar. Dennoch existieren im deutschsprachigen Raum bisher keine systematischen Untersuchungen über Arzthelferin-Patient-Kommunikation. In Aus- und Fortbildung spielen Techniken der Gesprächsführung eine untergeordnete Rolle. Im Projekt „FUNKTIONAL“ (1,2) stellte sich Frage nach mentalen Konstrukten schwierige resultierenden Konzepte Strategien. Darauf aufbauend wird spezielle Schulung Arzthelferinnen zum Thema...
Abstract Background Atrial fibrillation (AF) and heart failure (HF) are of growing prevalence increasing mortality. Radiofrequency ablation is safe effective for patients with AF HF. Prognosis might be improved in treated. However, there no prospective trial investigating efficacy safety cryoballon Objective To prospectively compare cryoballoon without HF (defined as LVEF ≤40%) terms efficacy. Methods Ongoing POLAR-HF a prospective, investigator-initiated, single-center, non-inferiority,...
Der Zufallsbefund des Magenwandtumors in der Computertomografie stellte sich Endosonografie als polyzystische septierte echoarme Raumforderung Submukosa dar. Durch die endosonografische Feinnadelpunktion konnte ein muzinöses Sekret gewonnen werden, Tumormarker oder Lipase konnten jedoch nicht dem nachgewiesen werden. Im Serum war CA 19 – 9 nahezu im Normbereich. Eine endoskopische Resektion großen über 5 cm messenden gelang nicht, da eine Art Zystenwand bereits mit den angrenzenden...
Chlamydien sind obligat intrazelluläre Erreger mit einem breiten Wirtsspektrum. Eine Infektion Chlamydia psittaci kann bei Menschen fieberhafte respiratorische Erkrankungen hervorrufen (Psittakose), die Übertragung von Vögeln auf den kommt häufig vor. Die Verlaufsform beim Rind nach intrabronchialer Inokulation ähnelt stark dem akuten Krankheitsbild Menschen. Bei der Suche neuen antichlamydialen Behandlungsstrategien erwies sich im Zellkulturmodell eine Kombination aus Chinolon und...
Kolorektale Metastasenchirurgie wird ergänzt von und konkurriert mit innovativen individualisierten multimodalen Therapieoptionen. Die Indikationsstellung ist geprägt Leitlinien, interdisziplinären Konzepten Patientenströmen. Während nationale internationale Leitlinien zur Lebermetastasenchirurgie differenziert Stellung nehmen, werden kolorektale Lungenmetastasen nur dem Attribut "Resektabilität" angesprochen. Im Rahmen eines peripheren zertifizierten onkologischen Zentrums integrierter...
Objective: We investigated whether patients who belong to the high risk group develop type-2 diabetes can be identified by medical assistants (MFA) in everyday routine of general practice means a few characteristics. The effectiveness diabetes-risk screening could improved selective approach are at risk. Method: As part feasibility study 'SeRiFIN', were between 20 and 50 years old and/or had positive family history approached trained MFA 6 practices. To determine diabetes, selected should...
Einleitung: Aufgrund von widersprüchlichen Berichten zur Wirksamkeit Doxyzyklin bei der Behandlung Chlamydieninfektionen wurde Effekt auf eine respiratorische Chlamydia psittaci (Cp) Infektion in einem bovinen Modell überprüft. Die Dosierung an die Zielspezies Mensch und Rind angepasst.