A5000082231- Effects and risks of endocrine disrupting chemicals
- Pluripotent Stem Cells Research
- Renal and related cancers
- Plant Genetic and Mutation Studies
- Epigenetics and DNA Methylation
Université Paris Cité
2022-2023
Commissariat à l'Énergie Atomique et aux Énergies Alternatives
2022-2023
Université Paris-Saclay
2022-2023
CEA Paris-Saclay
2022-2023
CEA Paris-Saclay - Etablissement de Fontenay-aux-roses
2022
Institut de Radiobiologie Cellulaire et Moléculaire
2022
Many endocrine disruptors have been proven to impair the meiotic process which is required for production of healthy gametes. Bisphenol A emblematic such disruptors, as it impairs prophase I and causes oocyte aneuploidy following in utero exposure. However, mechanisms underlying these deleterious effects remain poorly understood. Furthermore, increasing use BPA alternatives raises concerns public health. Here, we investigated foetal exposure two alternatives, bisphenol Diglycidyl Ether...
ABSTRACT Testicular cancer is an increasing burden in modern societies and the most common malignancy among young adult males. Environment contaminants, especially endocrine disrupting compounds (EDC), may play a significant role development of these cancers through epigenetic alterations occurring during fetal neonatal development. As long-term studies humans suitable experimental models with potential to develop testicular are lacking, no causal link can be established between disruptor...