A5012571577- Renal Transplantation Outcomes and Treatments
- Cytomegalovirus and herpesvirus research
- Cardiomyopathy and Myosin Studies
- Adenosine and Purinergic Signaling
- Organ Transplantation Techniques and Outcomes
- T-cell and B-cell Immunology
- Muscle Physiology and Disorders
- Immune Cell Function and Interaction
- Advanced Fluorescence Microscopy Techniques
Inserm
2022-2023
Nantes Université
2022-2023
Institut de Transplantation Urologie en Nephrologie
2022-2023
Center for Research in Transplantation and Translational Immunology
2021-2023
Laboratoire de Microbiologie et Génétique Moléculaires
2021
The mechanisms regulating CD8
The human immune system contains cells with either effector/memory or regulatory functions. Besides the well-established CD4+CD25hiCD127lo T (Tregs), we and others have shown that B can also functions since their frequency number are increased in kidney graft tolerance cell depletion as induction therapy may lead to acute rejection. On other hand, CD28-CD8+ represent a subpopulation potent In current study, tested hypothesis allograft rejection be linked an imbalance of cells. Based on large...
Duchenne muscular dystrophy (DMD) is a neuromuscular disease caused by mutations in the gene encoding dystrophin. It leads to repeated cycles of muscle fiber necrosis and regeneration progressive replacement fibers fibrotic adipose tissue, with consequent weakness premature death. Fibrosis and, particular, collagen accumulation are important pathological features dystrophic muscle. A better understanding development fibrosis crucial enable management DMD. Three-dimensional (3D)...