A5001365923- Immune cells in cancer
- Analytical Chemistry and Sensors
- Oral microbiology and periodontitis research
- Bone Metabolism and Diseases
- Nanoplatforms for cancer theranostics
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Gas Sensing Nanomaterials and Sensors
- Bone and Dental Protein Studies
- Advanced Chemical Sensor Technologies
- Photodynamic Therapy Research Studies
- Mesenchymal stem cell research
- 3D Printing in Biomedical Research
- Cancer, Hypoxia, and Metabolism
- S100 Proteins and Annexins
- Extracellular vesicles in disease
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Angiogenesis and VEGF in Cancer
- Bone health and osteoporosis research
- Stress Responses and Cortisol
- Sirtuins and Resveratrol in Medicine
- Autophagy in Disease and Therapy
- Telomeres, Telomerase, and Senescence
- Fibroblast Growth Factor Research
- Photoacoustic and Ultrasonic Imaging
- Cancer Research and Treatments
Air Force Medical University
2023-2025
Sun Yat-sen University Cancer Center
2024
Sun Yat-sen University
2024
Soochow University
2020-2021
Shaanxi Normal University
2021
Type H vessels couple angiogenesis with osteogenesis, while sympathetic cues regulate vascular and skeletal function. The crosstalk between nerves type in bone remains unclear. Here, we first identify close spatial connections bone, particularly metaphysis. Sympathoexcitation, mimicked by isoproterenol (ISO) injection, reduces mass. Conversely, beta-2-adrenergic receptor (ADRB2) deficiency maintains mass the physiological condition. In vitro experiments reveal indirect modulation of via...
Background: Type 2 diabetes (T2D) is a global metabolic condition associated with complications of multiple organs, including the bone. However, exact impact T2D on bone along disease progression, particularly in early phase, remains largely unknown. Methods: Four-week and sixteen-week high-fat diet (HFD) feeding-induced mouse models were established, glucose status was examined. Bone mass evaluated by micro-computed tomography (micro-CT), immunofluorescent (IF) staining performed for...
Clear cell renal carcinoma (ccRCC) is a malignancy with dismal prognosis, caused by the buildup of fat and glycogen. Sirtuin 1 (Sirt1) deacetylase that regulates lipid metabolism. In this study, we collected tumor paracancer tissues from 386 ccRCC patients followed their prognosis over an extended time period. The expression Sirt1 in these was assessed using immunohistochemistry, LinkedOmics database analysis identified differentially expressed genes associated Sirt1. survival curve...
<title>Abstract</title> Periodontitis is a prevalent and progressive detrimental disease which characterized by chronic inflammation, the immunopathological mechanisms being not yet fully understood. Mesenchymal stem cells (MSCs) play crucial roles as immunoregulators maintain tissue homeostasis regeneration, but their <italic>in vivo</italic> function in immunopathology periodontal deterioration still unclear. Here, we utilized multiple transgenic mouse models to specifically mark, ablate...