A5101809193- Endodontics and Root Canal Treatments
- Dental Trauma and Treatments
- Dental Radiography and Imaging
- Oral microbiology and periodontitis research
- Neuroscience and Neuropharmacology Research
- Dental Health and Care Utilization
- Neuropeptides and Animal Physiology
- Stress Responses and Cortisol
- Dental Research and COVID-19
- Nerve injury and regeneration
- Anesthesia and Neurotoxicity Research
- Neuroendocrine regulation and behavior
- Infectious Diseases and Tuberculosis
- Dental Erosion and Treatment
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- dental development and anomalies
- Analytical Chemistry and Sensors
- Pharmacological Receptor Mechanisms and Effects
- Cancer, Stress, Anesthesia, and Immune Response
- Nuclear Receptors and Signaling
- Genomics and Chromatin Dynamics
- Osteomyelitis and Bone Disorders Research
- Radiomics and Machine Learning in Medical Imaging
- Photoacoustic and Ultrasonic Imaging
- Sleep and Wakefulness Research
Xuzhou University of Technology
2023-2024
Xuzhou Medical College
2020-2024
Seattle Reproductive Medicine
2023-2024
Seattle Children's Hospital
2023
University of Washington
2009-2023
Shanxi Jincheng Anthracite Mining Group (China)
2020
University of Toledo
2010
Background The γ-aminobutyric acid–mediated (GABAergic) inhibitory system in the brain is critical for regulation of sleep–wake and general anesthesia. lateral septum contains mainly GABAergic neurons, being cytoarchitectonically divided into dorsal, intermediate, ventral parts. This study hypothesized that neurons participate control wakefulness promote recovery from Methods By employing fiber photometry, chemogenetic optogenetic neuronal manipulations, anterograde tracing, vivo...
Abstract Background/Aim A new bioceramic material iRoot BP Plus has been introduced and reported to have good biocompatibility, sealing ability antibacterial activity. It also be successfully used for procedures such as pulpotomy, pulp floor perforation repair so on. However, there are only a few reports on the use of in management traumatized teeth with an exposed pulp. The aim this study was investigate clinical radiographic outcomes partial pulpotomy immature permanent complicated crown...
Robust sex difference among humans regarding psychiatry- and pain-related behaviors is being researched; however, the use of female mice in preclinical research relatively rare due to an unchecked potential behavioral variation over estrous cycle. In present study, a battery are examined under physiological condition C57BL/6J different cycle phases: proestrus, estrous, metestrous, diestrous. Our results reveal that there no significant phases social interaction test, sucrose preference tail...
Pulp revascularisation with MTA sealing has been accepted as an alternative treatment for non-vital immature permanent teeth. Successful cases GIC were also reported, but lack of long-term researches.To evaluate outcomes using and canal-sealing materials in teeth.Clinical radiographic data 60 teeth treated (36.8 ± 12.4 months follow-up) reviewed. Of these, 28 sealed MTA, 32 GIC. Tooth survival, success rate, increases root length dentine wall thickness evaluated.Teeth group showed a similar...
Abstract Dextromethorphan is widely used in over‐the‐counter cough and cold medications. Its efficacy safety for infants young children remains to be clarified. The present study was designed use zebrafish as a model investigate the potential toxicity of dextromethorphan during embryonic larval development. Three sets embryos/larvae were exposed at 24, 48 72 h post fertilization (hpf), respectively, embryonic/larval Compared with hpf exposure sets, 24 set showed much higher mortality rates...
<italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">Objective:</i> Bacteria in the dental biofilm produceacid after consumption of carbohydrates which if left unmonitored leads to caries formation. We present O-pH, a device that can measure acidity and provide quantitative feedback assist oral health monitoring. xmlns:xlink="http://www.w3.org/1999/xlink">Method:</i> O-pH utilizes ratiometric pH sensing method by capturing fluorescence Sodium...
Sugar-rich diets and poor dental hygiene promote the formation of a biofilm (plaque) that strongly adheres to enamel surface fosters evolution aciduric bacteria. The acid contributes demineralization exterior tooth enamel, which accelerates after pH drops below critical value (∼5.5) for extended time periods resulting in need restorative procedures. Preventative techniques alert dentist caries-susceptible patients regarding vulnerability decay require clinical measure plaque activity....
Complicated crown-root fracture is considered a severe dental trauma and unlikely to heal without treatment. Usually, dentists have remove the loose coronal fragment of fractured tooth treat remaining part with multidisciplinary approaches. However, we observed spontaneous healing in two pediatric cases history complicated fractures over 4 years ago.In case 1, 12-year-old boy complained pain at 11 following an accidental fall 1 d ago. Clinical examination showed crack line on crown 11. Cone...
The same doses of anesthesia may yield varying depths in different patients. Clinical studies have revealed a possible causal relationship between deep and negative short- long-term patient outcomes. However, reliable index method the clinical monitoring detecting latency remain lacking. As burst-suppression is characteristic phenomenon anesthesia, present study investigated (BSL) subsequent ratio (BSR) to find an improved detection for onset intraoperative anesthesia. mice were divided...
Optical imaging modalities and therapy monitoring protocols are required for the emergence of non-surgical interventions treating infections in teeth to remineralize enamel. Current standard visual inspection, tactile probing radiograph caries detection is not highly sensitive, quantitative, safe. Furthermore, latter two viable options interproximal caries. We present preliminary results multimodal laser-based uorescence spectroscopy a blinded clinical study comparing topical therapies early...
Although anesthesia provides favorable conditions for surgical procedures, recent studies have revealed that the brain remains active in processing noxious signals even during anesthesia. However, whether and how these responses affect effect unclear. The ventrolateral periaqueductal gray (vlPAG), a crucial hub pain regulation, also plays an essential role controlling general Hence, it was hypothesized vlPAG may be involved regulation of by stimuli. Here, we found acute stimuli, including...
Objective: To identify tooth number abnormalities on pediatric panoramic radiographs based deep learning. Methods: Eight hundred of children aged 4 to 11 years meeting the inclusion and exclusion criteria were selected randomly assigned by writing programs in Python (version 3.9) training set (480 images), verification (160 images) internal test taken Department Pediatric Dentistry, Peking University School Hospital Stomatology between November 2012 August 2020. And all First Outpatient from...
We have developed a new tool to measure the acid production by plaque oral bacteria. Many species of bacteria metabolize sugars in food and produce organic acids that demineralize dental enamel leading formation cavities. Measuring acidity level before after sugar rinse can indicate susceptibility an individual tooth decay location active caries. In case study on two subjects, non-contact optics-based pH device was able track rinse. The fiber optic probe measures difficult access locations...