A5026706383- Insect and Pesticide Research
- Insect and Arachnid Ecology and Behavior
- Plant and animal studies
- Cardiac electrophysiology and arrhythmias
- Bee Products Chemical Analysis
- Ion channel regulation and function
- Pesticide Residue Analysis and Safety
- Cardiomyopathy and Myosin Studies
- Traditional Chinese Medicine Analysis
- Molecular Biology Techniques and Applications
- Cardiovascular Effects of Exercise
- Rice Cultivation and Yield Improvement
- Analytical Chemistry and Chromatography
- Biofield Effects and Biophysics
- Real-time simulation and control systems
- Embedded Systems Design Techniques
- Andrographolide Research and Applications
- Evacuation and Crowd Dynamics
- Micro and Nano Robotics
- Neuroscience and Neural Engineering
- Genetic Mapping and Diversity in Plants and Animals
- Flowering Plant Growth and Cultivation
- Insect-Plant Interactions and Control
- Fire Detection and Safety Systems
- Analytical chemistry methods development
Virginia Tech
2020-2025
Biomedical Research Institute
2020-2025
Carilion Roanoke Memorial Hospital
2021-2024
Concordia University
2024
Shanxi Jincheng Anthracite Mining Group (China)
2020
Dongfeng Motor Group (China)
2019
First Affiliated Hospital of Jinan University
2016
Beijing Forestry University
2011-2014
Chinese Academy of Medical Sciences & Peking Union Medical College
2011-2013
United States Government Accountability Office
2013
Abstract Tumour vasculature is generally disordered because of the production excessive angiogenic factors by tumour cells, which results in progression and reduces effectiveness radiotherapy or chemotherapy. Transient anti-angiogenic therapies that regulate vascular morphology function improve efficiency antitumour therapy are under investigation. Recombinant human endostatin (Endostar/rhES) a angiogenesis–disrupting agent has been used to treat non-small cell lung cancer (NSCLC) clinical...
BACKGROUND: Viral cardiac infection represents a significant clinical challenge encompassing several etiological agents, disease stages, complex presentation, and resulting lack of mechanistic understanding. Myocarditis is major cause sudden death in young adults, where current knowledge the field dominated by later phases pathological immune responses. However, little known regarding how can acutely induce an arrhythmogenic substrate before Adenovirus leading myocarditis, but due to species...
Small-scale robots capable of remote active steering and navigation offer great potential for biomedical applications. However, the current design manufacturing procedure impede their miniaturization integration various diagnostic therapeutic functionalities. Herein, submillimeter fiber that can integrate navigation, sensing, modulation functions are presented. These fabricated through a scalable thermal drawing process at speed 4 meters per minute, which enables ferromagnetic, electrical,...
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Cardiac voltage-gated sodium channel gain-of-function prolongs repolarization in the long-QT syndrome type 3 (LQT3). Previous studies suggest that narrowing perinexus within intercalated disc, leading to rapid depletion, attenuates LQT3-associated action potential duration (APD) prolongation. However, it remains unknown whether extracellular concentration modulates APD prolongation during gain-of-function. We hypothesized elevated and widened synergistically prolong LQT3. LQT3 was induced...
A fast gas chromatographic method for simultaneous determination of 50 organochlorine (OCP) and pyrethroid (PP) pesticides in Lycium barbarum L. is established. OCP PP were extracted from using acetonitrile, cleaned with alumina neutral-florisil column, eluted by mixed solvents ethyl acetate hexane (15 : 85, v/v). Selected identified HP-5 DB1701 capillary dual column detected electron-capture detector. Quantitative analysis was performed an external standard column. Results show that...
An efficient, fast, and easy-to-perform multi-residue method tracing pesticide residue based on ultrasonic extraction, mixed mode solid-phase extraction for purification GC–MS/MS analysis was successfully validated applied to the simultaneous determination of 100 residues in traditional Chinese medicine Flos Chrysanthemi samples. Results showed matrix-matched calibration curve linearity >0.9900 all target analytes. The recoveries obtained each ranged between 65.3 124.7%, RSD values were less...
Abstract Small-scale robots capable of remote active steering and navigation offer great potential for biomedical applications. However, the current design manufacturing procedure impede their miniaturization integration various diagnostic therapeutic functionalities. Here, we present a robotic fiber platform integrating navigation, sensing, functions at submillimeter scale. These consist ferromagnetic, electrical, optical, microfluidic components, fabricated with thermal drawing process....
Abstract Precise quantification of myocardial infarction is crucial for evaluating the therapeutic strategies. We developed a robust, color-based semi-automatic algorithm capable infarct region detection, isolation and with four different histological staining techniques, diffuse fibrosis in heart. Our method based on color difference non-infarct regions after staining. Mouse cardiac tissues stained Masson’s trichrome (MTS), hematoxylin eosin (H&E), 2,3,5-Triphenyltetrazolium chloride...
Background: Precise quantification of myocardial infarct size in therapeutic studies is a key prerequisite to ensure reliable and demonstrative results, supports the rapid translation findings into clinical practice. However, current methods are often highly dependent on hand tracing pose challenges that may impact accuracy, user ease, cost, timeliness image analysis. Here, we developed semi-automatic color-based algorithm capable region detection with four different histological staining...
Background: Ephaptic coupling (EpC), a form of intercellular communication between excitable cells, has been proposed to occur at the perinexus, sodium channel-rich nanodomain within intercalated disc (ID). Previous studies suggest that widening perinexus can influence EpC by altering ion availability, which in turn determines perinexal currents (INa). However, there is lack direct evidence for causal relationship and ephaptic coupling. This study aims develop novel approach directly measure...