- Heat transfer and supercritical fluids
- MicroRNA in disease regulation
- Subcritical and Supercritical Water Processes
- Pediatric health and respiratory diseases
- Nuclear Engineering Thermal-Hydraulics
- Heat Transfer and Boiling Studies
- Cancer-related molecular mechanisms research
- Advanced Combustion Engine Technologies
- Immune Response and Inflammation
- Heme Oxygenase-1 and Carbon Monoxide
- Inflammasome and immune disorders
- Advanced Glycation End Products research
- Circular RNAs in diseases
- RNA modifications and cancer
- Wheat and Barley Genetics and Pathology
- Fluid Dynamics and Mixing
- Ectopic Pregnancy Diagnosis and Management
- Hepatitis B Virus Studies
- Nuclear reactor physics and engineering
- Acute Kidney Injury Research
- RNA Research and Splicing
- Epigenetics and DNA Methylation
- Hepatocellular Carcinoma Treatment and Prognosis
- Mycotoxins in Agriculture and Food
- Cardiac Ischemia and Reperfusion
Wuhan University of Technology
2023-2025
North Dakota State University
2012-2025
Second Affiliated Hospital of Nanchang University
2024
Xi'an Jiaotong University
2012-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2008-2024
University of Science and Technology of China
2024
Nanchang University
2024
Guangdong University of Technology
2024
Hangzhou First People's Hospital
2024
Yancheng Institute of Technology
2024
The wheat pathogen Stagonospora nodorum produces multiple necrotrophic effectors (also called host-selective toxins) that promote disease by interacting with corresponding host sensitivity gene products. SnTox1 was the first effector identified in S. nodorum, and shown to induce necrosis on lines carrying Snn1. Here, we report molecular cloning validation of as well preliminary characterization mechanism underlying SnTox1-Snn1 interaction which leads susceptibility. using bioinformatics...
Abstract While Ru owns superior catalytic activity toward hydrogen oxidation reaction and cost advantages, the catalyst deactivation under high anodic potential range severely limits its to replace Pt benchmark catalyst. Unveiling mechanism of correspondingly developing protection strategies remain a great challenge. Herein, we develop atomic Pt-functioned nanoparticles with excellent anti-deactivation feature meanwhile employ advanced operando characterization tools probe underlying roles...
Abstract This is a prospective study of 182 women (38 yrs or younger) undergoing IVF-ET. Endometrial thickness, echo pattern and blood flow on transvaginal ultrasonography were recorded eight hours prior to hCG administration. The patients divided into three groups: A (n = 10) with undetectable endometrial flow; B 82) sub-endometrial C 90) both flow. According IVF-ET outcomes, all re-divided 1 non-pregnancy 92); 2 intrauterine pregnancy live fetus 70); 3 others 20 including biochemical...
<h3>Objective</h3> To evaluate the safety and efficacy of daclatasvir, an HCV NS5A inhibitor with pangenotypic activity, administered peginterferon-alfa-2a/ribavirin. <h3>Design</h3> In this Phase 2b double-blind, placebo-controlled study, treatment-naive adults genotype 1 (N=365) or 4 (N=30) infection were randomly assigned (2:2:1) to daclatasvir 20 mg 60 mg, placebo once daily plus weekly peginterferon-alfa-2a twice-daily ribavirin. Daclatasvir recipients achieving protocol-defined...
Abstract The quiescent centre (QC) in the Arabidopsis root apical meristem is essential for stem cell organization. Here we show that loss of REPRESSOR OF WUSCHEL1 (ROW1), a PHD domain-containing protein, leads to QC failure, defects differentiation and ectopic expression WUSCHEL-RELATED HOMEOBOX 5 ( WOX5 ) cells normally express ROW1 . wox5-1/row1-3 double mutants similar phenotypes wox5-1 indicating epistatic ROW1. specifically binds trimethylated histone H3 lysine 4 (H3K4me3) promoter...
Electrochemical hydrogenation of acetonitrile based on well-developed proton exchange membrane electrolyzers holds great promise for practical production ethylamine. However, the local acidic condition results in severe competitive reduction reaction and poor selection toward hydrogenation. Herein, we conduct a systematic study to screen various metallic catalysts discover Pd/C exhibits 43.8% ethylamine Faradaic efficiency at current density 200 mA cm-2 with specific rate 2912.5 mmol g-1...
Patients undergoing percutaneous coronary intervention react differently to antiplatelet drugs. Those with low responsiveness clopidogrel have a higher risk of cardiac ischemic events. The goal this study is conduct head-to-head comparison the safety and effectiveness intensified therapies (either double-dose [DOUBLE] or adjunctive cilostazol [TRIPLE]) conventional strategy (STANDARD) in patients after intervention.In single-center, randomized, controlled trial, we used thromboelastography,...
Abstract Tan spot and Septoria nodorum blotch (SNB) are important diseases of wheat caused by the necrotrophic fungi Pyrenophora tritici-repentis Parastagonospora nodorum, respectively. The P. effector (NE) Ptr ToxB causes tan when recognized Tsc2 gene. NE ToxA is produced both pathogens has been associated with development SNB Tsn1 Most work to study these interactions conducted in common wheat, but little done durum wheat. Here, quantitative trait loci (QTL) analysis a segregating...
MiR‐424 has been discovered to be involved in the chemoresistance of lung cancer. However, underlying mechanism by which miR‐424 played role unknown. Here, our study, investigate non‐small cell cancer (NSCLC), we have detected expression miR‐424‐3p and ‐5p NSCLC tissues paired normal control. Moreover, explore cells, were both re‐expressed knocked down using transient transfection with their respective mimics inhibitors. Cell viability, migration, invasion evaluated MTT, wound‐healing...
Parastagonospora nodorum is an economically important necrotrophic fungal pathogen of wheat. secretes effectors that target wheat susceptibility genes to induce programmed cell death (PCD). In this study, we cloned and functionally validated SnTox5 characterized its role in pathogenesis. We used whole genome sequencing, genome-wide association study (GWAS) mapping, CRISPR-Cas9-based gene disruption, gain-of-function transformation, quantitative trait locus (QTL) analysis, haplotype isoform...