A5112368372- Nutritional Studies and Diet
- Dietetics, Nutrition, and Education
- Obesity, Physical Activity, Diet
- Nutrition, Health and Food Behavior
- Conducting polymers and applications
- Organic Electronics and Photovoltaics
- Perovskite Materials and Applications
- Cancer Risks and Factors
- Genetic factors in colorectal cancer
- Colorectal Cancer Screening and Detection
- Glioma Diagnosis and Treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Human Health and Disease
- Electrospun Nanofibers in Biomedical Applications
- Food Security and Health in Diverse Populations
- Histone Deacetylase Inhibitors Research
- Urban Design and Spatial Analysis
- Smart Parking Systems Research
- RNA modifications and cancer
- Disaster Management and Resilience
- Gastrointestinal Tumor Research and Treatment
- Microbial metabolism and enzyme function
- Colorectal Cancer Treatments and Studies
- Technology Use by Older Adults
- Endometrial and Cervical Cancer Treatments
Second Affiliated Hospital of Dalian Medical University
2017-2025
Dalian Medical University
2017-2025
Shanghai Polytechnic University
2024
Donghua University
2022-2024
Southern University of Science and Technology
2022-2024
Wuhan University of Technology
2022
Dalian University
2019
Qilu Hospital of Shandong University
2018
Tianjin Children's Hospital
2018
Division of Undergraduate Education
2001-2012
Brain metastasis (BM) is a leading cause of mortality in patients with non-small cell lung cancer (NSCLC). However, the molecular mechanisms underlying BM NSCLC remain largely unknown because lack models to accurately investigate such dynamic and complex process. Here we developed multi-organ microfluidic chip as new methodological platform study BM. The consisted two bionic organ units – an upstream “lung” downstream “brain” characterized by functional “blood–brain barrier (BBB)” structure,...
Traumatic brain injury induces potent inflammatory responses that can exacerbate secondary blood-brain barrier (BBB) disruption, neuronal injury, and neurological dysfunction. Dexmedetomidine is a novel α2-adrenergic receptor agonist exert protective effects in various central nervous system diseases. The present study was designed to investigate the neuroprotective action of dexmedetomidine mouse traumatic model, explore possible mechanisms. Adult male C57BL/6J mice were subjected...
Abstract The diversity in molecular structures and solution processability of non‐fullerene acceptors (NFAs), particularly those containing selenium (Se), plays a pivotal role advancing organic solar cells (OSCs). Among various design strategies, the introduction atoms, characterized by their large covalent radius, loose electron cloud, strong polarization properties, can enhance intermolecular Se‐Se interactions improve electron‐donating capability π‐cores. This approach is considered...
Topoisomerase IIα (TOP2A) plays an oncogenic role in multiple tumor types. However, no pan-cancer analysis about the function and upstream molecular mechanism of TOP2A is available. For first time, we analyzed potential roles 33 cancer types via The Cancer Genome Atlas (TCGA) database. Overexpression was existed almost all types, related to poor prognosis advanced pathological stages most cases. Besides, high frequency genetic alterations observed several some Moreover, conduct miRNAs...
The emergence of Y-series non-fullerene acceptors (NFAs) has inspired the development various materials for high-performance organic solar cells (OSCs). In this work, a novel asymmetric NFA named Y6-1OBO bearing branched alkyl and alkoxy side chains was designed synthesized. When diiodomethane selected as solvent additive, Y6-1OBO-based devices achieved an efficiency 18.02% with open-circuit voltage 0.93 V fill factor 77.1%, which is much higher than that Y6-1O-based (16.81%). effects...
Although accumulating evidence has verified the relationship between CCNA2 and cancers, no pan-cancer analysis about function upstream molecular mechanism of is available. For first time, we analyzed potential oncogenic roles in 33 cancer types via The Cancer Genome Atlas (TCGA) database. Overexpression widespread almost all types, it related to poor prognosis advanced pathological stages most cases. Moreover, conducted miRNAs lncRNAs establish regulatory networks kidney renal clear cell...
Nonfused ring electron acceptors (NFREAs) have emerged as promising materials for commercial applications in organic solar cells due to their straightforward synthesis process and cost-effectiveness. The rational design of structural frameworks is crucial enhancing device efficiency. In this study, we explore the use maleimide thiophene key building blocks, employing cyclization engineering techniques. Additionally, cyclopentanedithiophene was chosen bridging unit, coupled with fluorinated...
Background The purpose of this study is to employ a competing risk model based on the Surveillance, Epidemiology, and End Results (SEER) database identify prognostic factors for elderly individuals with sigmoid colon adenocarcinoma (SCA) compare them classic Cox proportional hazards model. Methods We extracted data from patients diagnosed SCA registered in SEER between 2010 2015. Univariate analysis was conducted using cumulative incidence functions Gray’s test, while multivariate performed...
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal of digestive system. They usually occur in gastrointestinal tract. However, we discovered a rare phenomenon which small cell carcinoma infiltrated GIST patient. The patient came to hospital and presented with chest tightness shortness breath for 2 months dry cough half month. As ancillary tests were refined, it was that he also had lesion pelvic cavity. After pathological examination core needle biopsy (CNB) samples from...
China has the largest and fastest-growing population of people with dementia in world. It become urgent to create environments urban areas where these populations can live thrive. This paper provides an in-depth case study activity centres cafes public spaces China. highlights contemporary social issues, such as lack universal education dementia-friendly spaces. Through examination challenges from perspective built environment, this proposes cognitively friendly design strategies at levels...
With the rapid development of Internet Things (IoT) technology, IoT technology has become popular in many fields and effectively improved work efficiency practical applications. In current operation parking lot, gradual increase devices caused a certain degree management difficulties, based on this situation, paper designs lot system with device function, which three subsystems, corresponding to The sub-systems, correspond IOT information management, vehicle personnel management. This...
Brain metastasis (BM) is a leading cause of mortality in patients with non-small cell lung cancer (NSCLC). However, the molecular mechanisms underlying BM NSCLC remain largely unknown because we lack models to accurately investigate such dynamic and complex process. Here developed multi-organ microfluidic chip provided new methodological platform study BM. The consisted two bionic organ units – an upstream “lung” downstream “brain” characterized by functional “blood-brain barrier (BBB)”...