Zhiguang Lin

ORCID: 0009-0005-0876-5707
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About
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Research Areas
  • CNS Lymphoma Diagnosis and Treatment
  • Lymphoma Diagnosis and Treatment
  • Glioma Diagnosis and Treatment
  • Advancements in Battery Materials
  • Supercapacitor Materials and Fabrication
  • Advanced Battery Materials and Technologies
  • Microgrid Control and Optimization
  • Multilevel Inverters and Converters
  • MRI in cancer diagnosis
  • Electrocatalysts for Energy Conversion
  • Geochemistry and Geologic Mapping
  • Soil Geostatistics and Mapping
  • HVDC Systems and Fault Protection
  • Advanced DC-DC Converters
  • Power System Optimization and Stability
  • Advanced battery technologies research
  • Graphene research and applications
  • Water Quality Monitoring Technologies
  • Circular RNAs in diseases
  • Soil and Land Suitability Analysis
  • Inorganic Fluorides and Related Compounds
  • Acute Lymphoblastic Leukemia research
  • Anodic Oxide Films and Nanostructures
  • Advanced Sensor and Energy Harvesting Materials
  • Viral-associated cancers and disorders

Chinese Academy of Sciences
2017-2025

Fudan University
2013-2025

Huashan Hospital
2013-2025

Royal Society of Chemistry
2024

Centre National pour la Recherche Scientifique et Technique (CNRST)
2024

Xiamen Institute of Rare-earth Materials
2022-2024

University of Chinese Academy of Sciences
2024

Fujian Institute of Research on the Structure of Matter
2023-2024

State Grid Corporation of China (China)
2022-2023

Institute of Intelligent Machines
2017

The pathological diagnosis of primary central nervous system lymphoma (PCNSL) by stereotactic brain biopsy and craniotomy is not often applicable due to the high cost associated complications. In recent years, some biomarkers in cerebrospinal fluid (CSF), including interleukin 10 (IL-10), microRNAs, CXC chemokine ligand 13 (CXCL13), have been reported be with PCNSL. However, this conclusion was controversial. Therefore, study test whether Th17 cell-related cytokines could used distinguish...

10.2147/cmar.s255482 article EN cc-by-nc Cancer Management and Research 2020-07-01

<title>Abstract</title> Ionogels have emerged as versatile materials with potential applications in flexible electronics and soft robotics. However, preparing high-performance ionogels high conductivity good mechanical strength remains challenging. Here, we report the development of a novel supramolecular ionogel wearable device for monitoring stimulus-response behavior aquatic animals. The integration silver nanowires (AgNWs) endows electrical (0.56 S m<sup>− 1</sup>) robustness (strain...

10.21203/rs.3.rs-5757703/v1 preprint EN cc-by Research Square (Research Square) 2025-01-15

Purpose: Current prognostic scoring systems for newly diagnosed primary central nervous system lymphoma (PCNSL), such as IELSG score and MSKCC score, are widely used but have limitations in clinical practice. This study aimed to develop a novel model based on real data compare it with existing systems. Patients Methods: A total of 288 patients PCNSL were recruited. randomly allocated the development validation cohorts. The least absolute shrinkage selection operator (LASSO) regression...

10.2147/jir.s498121 article EN cc-by-nc Journal of Inflammation Research 2025-02-01

High-dose methotrexate (HD-MTX)-based chemotherapy regimen is the first-line treatment of primary central nervous system lymphoma (PCNSL). At present, doses MTX in range 3.5-8 g/m2 are frequently used. However, optimal dose for PCNSL remains controversial. The purpose this real-world study was to compare efficacy and toxicity HD-MTX patients with untreated PCNSL.Immunocompetent adults newly diagnosed between January 2015 December 2018 were investigated followed up June 2019. All patients'...

10.2147/cmar.s322467 article EN Cancer Management and Research 2021-08-01

Background Primary central nervous system lymphoma (PCNSL) is an aggressive extranodal non-Hodgkin with a poor prognosis. We aimed to evaluate the prognostic impact of circulating NK cells in PCNSL. Materials and methods Patients diagnosed PCNSL who were treated at our institution between December 2018 2019 retrospectively screened. Patient variables including age, sex, Karnofsky performance status, diagnostic methods, location lesions, lactate dehydrogenase, cerebrospinal fluids (CSF),...

10.3389/fimmu.2023.1191033 article EN cc-by Frontiers in Immunology 2023-06-22

A fast fluoride ion conductor with mixed components of hexagonal, cubic and orthorhombic phases is synthesized to achieve high conductivity.

10.1039/d4nj01063a article EN New Journal of Chemistry 2024-01-01

Based on theoretical calculations, the molecule predominantly generated by combination of sodium with graphite is identified as NaC186. Consequently, this compound has a relatively limited capacity for storage, amounting to only 36 mA h g–1. In study, we construct FeSe2 intercalation compounds (FeSe2-GIC) in situ inserting between interlayers hydrothermal process. The resulting FeSe2-GIC material then subjected ball milling form FeSe2-GIC-BM. was found be tightly intercalated within layers,...

10.1021/acsaelm.3c01355 article EN ACS Applied Electronic Materials 2023-11-30

Ruddlesden–Popper (R-P) perovskite oxides have attracted much attention as highly active and stable bifunctional materials for the oxygen evolution reaction (OER)/oxygen reduction (ORR) in alkaline solutions due to nonuse of precious metal elements. Herein, a triple (H+, O2–, electron) conductive R-P oxide, La1.2Sr0.8Ni0.6Fe0.4O4+δ, was prepared, valence state transition cations oxidized (O–/O22–) structure tuned by low-temperature fluorine substitution treatment. The homogeneous...

10.1021/acs.energyfuels.4c00553 article EN Energy & Fuels 2024-04-17

To solve the stability problem of large-scale offshore wind power integration and transmission, this paper proposed a topology distributed medium voltage DC collection high transmission. The has three series boosters. first stage booster is realized through direct connection turbine generators, second Modular Multilevel Direct-current Converter (MMDC), third side ports MMDC. method its system characteristics are introduced. typical control strategy MMDC analyzed, providing support for...

10.1109/ispec58282.2023.10402895 article EN 2021 IEEE Sustainable Power and Energy Conference (iSPEC) 2023-11-28

// Ni Fan 1,* , Lu Zhang Xiaoping Xu 1 Bobin Chen Zhu Pei Li Zi Tianling Ding Yan Ma Yuan and Zhiguang Lin Department of Hematology, Huashan Hospital, Fudan University, Shanghai, China Correspondence to: Xu, email: Chen, Keywords : PCNSL, methotrexate, idarubicin, PFS Received September 06, 2016 Accepted February 07, 2017 Published March 04, Abstract Primary central nervous system lymphoma (PCNSL) is a rare form non-Hodgkin with poor long-term survival. This study assessed methotrexate (MTX)...

10.18632/oncotarget.15899 article EN Oncotarget 2017-03-04

The aim was to determine the clinical and cytogenetic characteristics of non-Hodgkin's lymphoma (NHL) in Shanghai. A retrospective analysis conducted 516 patients with NHL. Patient data, including age, sex, diagnosis, immunophenotypes, karyotypes, were collected. median age 58 years. There a male predominance all NHL, except extranodal marginal zone mucosa-associated lymphoid tissue. Patients B cell NHL (1.5%) expressed CD3. T (11.5%) CD20. Epstein–Barr virus latent integral membrane protein...

10.1179/1607845413y.0000000097 article EN Hematology 2013-10-01

Extreme events can cause damages to transmission system equipment, resulting in a major power outage. In disturbance scenario, local distributed energy resources (DERs) and switches be fully utilized restore loads, which is critical for enhancing the resiliency. A service restoration model distribution network with soft open point (SOP) proposed, ZIP loads are considered. Traditional tie switch (TS) operations output capabilities of DERs coordinated outage area. On this basis, SOP...

10.1016/j.egyr.2022.08.063 article EN cc-by-nc-nd Energy Reports 2022-08-22

The present study aimed to investigate the curative effect of high-dose methotrexate (HD-MTX) combined with teniposide (Vm26) vs. HD-MTX alone in treatment primary central nervous system lymphoma (PCNSL), order provide data for assisting decisions associated clinical treatment. Data from 56 patients PCNSL admitted Shanghai Huashan Hospital (Shanghai, China) January 2009 December 2014 were included into study. Clinical data, effects and prognosis these two groups retrospectively analyzed...

10.3892/ol.2020.11328 article EN Oncology Letters 2020-01-22

Background: Due to the poor prognosis and rising occurrence, there is a crucial need improve diagnosis of Primary Central Nervous System Lymphoma (PCNSL), which rare type non-Hodgkin's lymphoma. This study utilized targeted metabolomics cerebrospinal fluid (CSF) identify biomarker panels for improved or differential primary central nervous system lymphoma (PCNSL). Methods: In this study, cohort 68 individuals, including patients with non-malignant disease controls, other brain tumors, was...

10.3389/fmolb.2023.1257079 article EN cc-by Frontiers in Molecular Biosciences 2023-10-31

PCNSL is a heterogeneous and aggressive non-Hodgkin lymphoma with poor prognosis. The present study revealed that 3D-ASL MR perfusion imaging-derived rCBF values pre- posttreatment can be used as predictors for patients newly diagnosed PCNSL. Furthermore, this the first identifying rCBFmean an independent predictor overall survival. Different from traditional prognostic scoring system, provided noninvasive MRI technique requires no contrast agent or radiation exposure. Inclusion of sequence...

10.58530/2023/1580 article EN Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition 2024-08-14
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