A5087897840- Lymphoma Diagnosis and Treatment
- Advanced Radiotherapy Techniques
- Head and Neck Cancer Studies
- Inflammatory mediators and NSAID effects
- Cancer-related molecular mechanisms research
- Management of metastatic bone disease
- Esophageal Cancer Research and Treatment
- Systemic Lupus Erythematosus Research
- Brain Metastases and Treatment
- Vasculitis and related conditions
- Lung Cancer Treatments and Mutations
- Glioma Diagnosis and Treatment
- Sinusitis and nasal conditions
- Atherosclerosis and Cardiovascular Diseases
- Hepatocellular Carcinoma Treatment and Prognosis
- Osteoarthritis Treatment and Mechanisms
- Gastric Cancer Management and Outcomes
- Lung Cancer Research Studies
- Cancer Immunotherapy and Biomarkers
- Additive Manufacturing Materials and Processes
- dental development and anomalies
- Cancer Mechanisms and Therapy
- Ear and Head Tumors
- High-Temperature Coating Behaviors
- Cancer Risks and Factors
Huazhong University of Science and Technology
2024-2025
Hebei Medical University
2020-2025
Fourth Hospital of Hebei Medical University
2020-2025
Tongji Hospital
2024-2025
Anhui University
2025
Union Hospital
2025
Wuhan Union Hospital
2025
Fuzhou University
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2012-2023
Peking Union Medical College Hospital
1998
Abstract Myocardial infarction (MI) poses a significant threat to human health. Current treatments emphasize early revascularization restore blood supply the myocardium, often overlooking extensive oxidative damage and autophagy dysfunction resulting from reactive oxygen species (ROS) release after MI. Therefore, timely effective interventions clear ROS in stages of MI are crucial for inhibiting pathological progression restoring cardiac function. This study constructed ROS‐responsive...
Abstract As a class of emerging photoluminescent materials, hybrid halide crystals have drawn research attention for their potential application in the fields light‐emitting, security, and waveguide. Nevertheless, containing antimony with long‐term stability tunable light emission are still increasingly demand. In this work, serial new (BZA) 2 ZnCl 4 ·2H O: x Sb 3+ ( = 0–0.2, represents reaction ratio) SbCl 5 synthesized (BZA 2,4‐diamino‐6‐phenyl‐1,3,5‐triazine). crystals, cations replace...
In this study, we determined serum 25-hydroxyvitamin D [25(OH) D] levels in serum, and investigated their associations with risk of recurrent stroke mortality a 24-month follow up study Chinese patients first-ever ischemic stroke. preplanned post hoc analysis, 25(OH) NIH scale (NIHSS) were measured at the time admission cohort We used logistic regression model to assess relationship between or mortality. The follow-up rate was 98.2% 220 patients. Of 216 patients, 18.5% (95%CI: 13.3%–23.7%)...
Esophageal squamous-cell carcinoma (ESCC) is commonly treated with radiotherapy; however, radioresistance hinders its clinical effectiveness, and the underlying mechanism remains elusive. Here, we develop patient-derived xenografts (PDXs) from 19 patients ESCC to investigate mechanisms driving radioresistance. Using RNA sequencing, cytokine arrays, single-cell reveal an enrichment of cancer-associated fibroblast (CAF)-derived collagen type 1 (Col1) tumor-cell-derived CXCL1 in non-responsive...
Immunotherapy has demonstrated potential in the treatment of esophageal cancer (EC); however, overall response rate (ORR) remains below 30% among EC patients. Herein, use peripheral blood lymphocyte subsets as biomarkers was explored to evaluate efficacy immunotherapy this patient population. Sixty-three patients were enrolled. The diagnosed with and treated immune checkpoint inhibitors (ICIs) at Fourth Hospital Hebei Medical University from December 2019 June 2023. Kaplan-Meier (KM)...
CHI3L1 has been identified as a protein expressed in various tissues and tumor tissues, playing critical roles diverse physiological pathological processes such inflammation, oxidative stress, cell death, immune regulation. Previous studies have indicated that the elevated levels synovial fluid serum of osteoarthritis patients may serve biomarker for osteoarthritis. However, mechanisms by which affects chondrocytes significance its upregulated expression remain to be fully elucidated. This...
Immune Checkpoint Inhibitors (ICIs) have dramatically revolutionized the therapeutic approaches by which we treat a series of cancers accompanied immune-related adverse events (irAEs). Herein, reported an intrahepatic cholangiocarcinoma male patient with history ankylosing spondylitis developing pulmonary arterial hypertension (PAH) under ICI combined therapy pembrolizumab and lenvatinib. The indirect measurement cardiac ultrasound showed artery pressure (PAP) 72mmHg after 21 three-week...
Esophagogastric junction adenocarcinoma (EJA) has increased in recent years, and it exhibits a poor prognosis short survival period for patients. Hydrogen sulfide (H<sub>2</sub>S) plays an important role the pathogenesis of cancer been studied as diagnostic factor some tumor diseases. However, few studies have explored value H<sub>2</sub>S EJA. In present study, total 56 patients with early‑stage EJA were enrolled while 57 healthy individuals selected control group. Clinical features...
Journal Article Three novel mutations of the EDA gene in Chinese patients with X‐linked hypohidrotic ectodermal dysplasia Get access J. Zhao, Zhao Department Medical Genetics and National Key Laboratory Molecular Biology, Institute Basic Sciences, Academy Sciences & Peking Union College, Beijing 100005, China Search for other works by this author on: Oxford Academic Google Scholar R. Hua, Hua X. Y. Meng, Meng Ao, Ao Q. Liu, Liu D. Shang, Shang M. Sun, Sun W.H‐Y. Lo, Lo Zhang Correspondence:...
Gastric cancer is a significant global malignancy with poor prognosis. Although the emergence of immune checkpoint inhibitors (ICIs) prolonged duration survival, resistance and progression are inevitable. We aim to evaluate effectiveness programmed death-1 (PD-1) in immunotherapy beyond (IBP). divided advanced gastric patients who received two lines into same regimen group (with PD-1 inhibitor regime after IBP) different IBP). Statistical analysis conducted compare patient characteristics...
Objective MicroRNA-related single-nucleotide polymorphisms (miR-SNPs) can alter microRNA (miRNA) expression profiles, thereby influencing the risk of rheumatic diseases. Herrin a case control study, six miR-SNPs in miRNA processing machinery genes, namely RAN (rs14035), XPO5 (rs11077), Dicer (rs3742330), GEMIN3 (rs197412), GEMIN4 (rs2740348), and TNRC6B (rs9623117), were genotyped to assess their correlation with systemic lupus erythematosus (SLE). Methods We included 119 patients SLE 130...
Introduction: Smoking is well-known to increase cancer risk, particularly risk of lung cancer, and negatively affects efficacy treatment. However, recent evidence suggests that among patients, paradoxically, smokers respond treatment better than non-smokers. We propose conduct a focused review meta-analysis compare response drug between smoking non-smoking patients. Methods design: will collect data from large clinical trials therapies for patients which have included search PubMed, PMC/...