A5061813648- Primate Behavior and Ecology
- Adipose Tissue and Metabolism
- Diet and metabolism studies
- Animal Behavior and Reproduction
- Muscle Physiology and Disorders
- Gut microbiota and health
- Bat Biology and Ecology Studies
- Amphibian and Reptile Biology
- Adipokines, Inflammation, and Metabolic Diseases
- Animal Behavior and Welfare Studies
- Dietary Effects on Health
- Exercise and Physiological Responses
- Medicinal Plant Pharmacodynamics Research
- Cardiovascular Health and Risk Factors
- Genetics, Aging, and Longevity in Model Organisms
- Crustacean biology and ecology
- Genomics, phytochemicals, and oxidative stress
- Tea Polyphenols and Effects
- Genetic diversity and population structure
- Synthesis and Biological Evaluation
- Neurobiology and Insect Physiology Research
- Gestational Diabetes Research and Management
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Wound Healing and Treatments
- Synthesis and biological activity
Zhengzhou University
2015-2024
China Tobacco
2023
The University of Sydney
2018-2019
Chinese Academy of Sciences
2014
Institute of Oceanology
2014
A question of considerable importance is why some animals are able to succeed on a wide range diets whereas others more tightly constrained. Theory predicts that generalists should show flexible response for macronutrient regulation in the face ecologically driven constraint nutritional balance available foods, which modeling framework geometry has been quantitatively characterized as an "equal distance" regulatory model. This prediction, empirical support from several laboratory studies...
Increasing energy expenditure by activating thermogenesis in brown and beige adipocytes is a critical approach to protect against obesity. Here, we investigated the action mechanism of natural polymethoxyflavone on adaptive high-fat diet-induced obesity mouse model. Nobiletin treatment significantly ameliorated obesity, alleviated whitening adipose tissue, promoted browning white tissue mice fed diet. Gut microbiota analysis metabolomic profiling revealed that nobiletin resulted composition...
Slow oxidative myofibers play an important role in improving muscle endurance performance and maintaining body energy homeostasis. However, the targets means to regulate slow proportion remain unknown. Here, we show that tangeretin (TG), a natural polymethoxylated flavone, significantly activates myofibers-related gene expression increases type I proportion, resulting improved aerobic metabolism mice. Proteomics, molecular dynamics, cellular thermal shift assay (CETSA) drug affinity...
Recent advances in niche theory have stressed the importance of understanding dietary generalism at multiple levels, including range habitat and foods exploited by a species, within populations, patterns nutrient intake. Here we apply this framework to examine strategy Macaca mulatta, primate species that is second only humans their breadth geographical distribution, occupy diverse ecological habitats from cold temperate tropical latitudes. A recent study showed Taihangshan subspecies ( M....
Sesamin, a major lignin mainly found in sesame (Sesamum indicum) oil and seeds, has been demonstrated to possess lipoclasis-promoting, antiobesity, antidiabetic effects. Irisin is newly discovered myokine that attracted great interest as key target prevent/treat obesity its related metabolic diseases. However, the effect potential mechanism of sesamin on FNDC5/irisin are still vacant. In this study, we showed treatment increased activation regulated SIRT1, PGC-1α, p-SMAD3/SMAD3 expression...
Food supply is one of the major drivers animal behavior, and gut microbiome an important mediator between food its effects on physiology. However, predicting outcome diet change consequences for has proven extremely challenging. We propose this reflects processes occurring at different scales. Inadequate accounting multi-level complexity nutrition (nutrients, foods, diets) obscures influence subsequently animal. Here, we present a detailed year-round, analysis changes in wild population...
Obesity is a serious public health issue worldwide. Growing evidence demonstrates the efficacy of ketogenic diet (KD) for weight loss, but there may be some adverse side effects such as dyslipidemia and hepatic steatosis. Aerobic exercise widely recognized approach improving these metabolic markers. Here we explored combined impacts KD moderate aerobic an 8-week intervention on body fat serum biomarkers, lipid metabolism in mouse model high-fat diet-induced obesity. Both with significantly...
Naringin, a natural flavonoid mainly found in citrus fruit, has been reported to exert positive effect on improving skeletal muscle health. However, the effects and potential mechanisms of naringin fiber switching is still unclear. Here, we discovered that oral administration increased low-speed running time, four-limb hanging body oxygen consumption mice, enhanced aerobic enzyme activity, MyHC I expression, slow-twitch percentage mice muscle. By contrast, decreased α-GPDH IIb fast-twitch...
Growing evidence supports the efficacy of ketogenic diets for inducing weight loss, but there are also potential health risks due to their unbalanced nutrient composition. We aim at assessing relative effectiveness a balanced diet and reversing metabolic syndrome in diet-induced C57BL/6J mouse model. Mice were fed high-fat induce obesity. Obese individuals then either or as an obesity intervention. Serum, liver, fat faecal samples analysed. observed that both interventions led significant...
Abstract Nutrient intake of animals is influenced by an interplay external and internal factors, such as food availability reproductive state, respectively. We used the nutritional geometry framework to analyze individual‐based data on energy nutrient in relation state a population rhesus macaques ( Macaca mulatta tcheliensis ), which live harsh high‐latitude habitat, Taihangshan mountains China, exhibit strong seasonality. combined over 3‐year period availability, diets, output, components...
We aimed to explore the relationship between dietary patterns and gestational diabetes mellitus (GDM) during pre-pregnancy six months using principal component analysis (PCA) geometric framework for nutrition (GFN).
Abstract Background Within multi-male and multi-female mammalian societies, paternity assignment is crucial for evaluating male reproductive success, dominance hierarchy, inbreeding avoidance. It is, however, difficult to determine because of female promiscuity during reproduction. Noninvasive molecular techniques (e.g., fecal DNA) make it possible match the genetic father his offspring. In current study, a troop free-ranging Taihangshan macaques ( Macaca mulatta tcheliensis ) in Mt. area,...
To investigate the relationship between light sensing systems in eye and circadian oscillators hypothalamus of subterranean rodents, we studied Mandarin voles (Lasiopodomys mandarinus) that spend their entire lives under dark conditions with degenerated eyes, compared oscillatory expression patterns clock genes aboveground relatives, Brandt's (L. brandtii). Individuals both vole species were kept a 12-h light/12-h condition or continuous for 4 weeks. In species, expressions most showed...
Evolving evidence supports the role of ketogenic diet (KD) in weight loss. However, no coherent conclusions are drawn on its impact effect KD exercise and antioxidant capacity after loss obese individuals. We evaluated performance, energy metabolism mice using high-fat diet-induced mice, used normal (ND) intervention, respectively, to provide a theoretical basis for further study health effects KD. Our results showed that 8-week significantly reduced body improved performance treadmill...