- Dental Implant Techniques and Outcomes
- Oral microbiology and periodontitis research
- Oral Health Pathology and Treatment
- Dental materials and restorations
- Salivary Gland Disorders and Functions
- Ovarian cancer diagnosis and treatment
- Oral and Maxillofacial Pathology
- Genetic factors in colorectal cancer
- Bone Tissue Engineering Materials
- Uterine Myomas and Treatments
- Oral and gingival health research
- Orthopaedic implants and arthroplasty
- Cancer Genomics and Diagnostics
- PARP inhibition in cancer therapy
- Lung Cancer Treatments and Mutations
- NF-κB Signaling Pathways
- Periodontal Regeneration and Treatments
- Bone and Dental Protein Studies
- Celiac Disease Research and Management
- Helicobacter pylori-related gastroenterology studies
- Magnetic and Electromagnetic Effects
- Electromagnetic Fields and Biological Effects
- Melanoma and MAPK Pathways
- Tattoo and Body Piercing Complications
- Infections and bacterial resistance
Marche Polytechnic University
2002-2017
Istituto Nazionale di Riposo e Cura per Anziani
2016
Ospedali Riuniti di Ancona
1998-2014
Ancon (United Kingdom)
2007
University of Naples Federico II
1999
CTO Hospital
1997
Eastman Chemical Company (Germany)
1996
A series of 110 cases oral squamous cell carcinoma (SCC) together with six lymph node and one distant metastatic lesions was analysed for expression survivin, a recent apoptosis inhibitor, by immunohistochemistry Western blotting. In total, 91 (82.7%) all metastasis (seven cases, 100%) were positive survivin expression, weighted scores ranging from 1 to 4. contrast, normal epithelium did not express survivin. There no significant correlation between age, sex, tumour size, the presence...
P-cadherin, a transmembrane molecule similar to E-cadherin involved in the cell-cell adhesion, and catenins form complexes between its cytoplasmic domain cytoskeleton. Five cell lines, 108 specimens of oral squamous carcinomas (OSCC), 9 metastasis 10 normal mucosa were examined evaluate P-cadherin expression cellular localization by immunohistochemistry western-blotting. In there was membranous only basal parabasal layers. 91 cases (84%) showed membranous/cytoplasmic positivity, whereas 17...
The mucosa around implants and the gingiva teeth respond to plaque formation with development of an inflammatory lesion which has similar magnitude histological features. Different cell types in inflamed healthy periodontal peri-implant tissues are capable producing a variety important pro-inflammatory anti-inflammatory cytokines growth factors mediate host response. aim this study is compare expression levels detectable soft tissue two single-implant crowns supported either by zirconia or...
Scientific interest in saliva as a diagnostic matrix has greatly increased over the last decade. The Triage® screening test (Biosite Diagnostics), rapid immunological used to detect recreational drugs urine, was compare two biological matrixes: non-conventional one, saliva, and traditional urine. Twenty-one drug abusers collected one urine specimen, both of which were tested with Triage kit. Data validated by gas-chromatography-mass-spectrometry (GC-MS). Results positive for methadone 9 14...
Since Raloxifene, a drug used in osteoporosis therapy, inhibits the osteoclast functions but not osteoblast functions, it could improve recovery during implant surgery. This preliminary report describes simple method to link, through covalent bond, Raloxifene titanium by interfacing with (3-aminopropyl)-Triethoxysilane as assessed IR-FT and SEM. To evaluate biological response of osteoblast-like cells this implant, we compared expression gene profiling cell cultures on conjugated normal DNA...
Coral is used worldwide for bone reconstruction. The favorable characteristics that make this material desirable implantation are (i) osteoinduction, (ii) and osteoconduction. These proprieties have been demonstrated by in vivo studies with animal models clinical trials over a twenty-year period. Also poly(2-hydroxyethylmethacrylate) [poly(HEMA)] widely biomaterial. By using coral poly(HEMA), scaffold reconstruction application has recently synthesized. Cytological, histological genetic...