A5045800539- Dental Implant Techniques and Outcomes
- Periodontal Regeneration and Treatments
- Dental Radiography and Imaging
- Oral and Maxillofacial Pathology
- dental development and anomalies
- Endodontics and Root Canal Treatments
- Oral microbiology and periodontitis research
- Dental materials and restorations
- Mesenchymal stem cell research
- Oral and gingival health research
- Head and Neck Cancer Studies
- Oral Health Pathology and Treatment
- Bone Tissue Engineering Materials
- Tissue Engineering and Regenerative Medicine
- Bone and Dental Protein Studies
- Genomic variations and chromosomal abnormalities
- Orthodontics and Dentofacial Orthopedics
- Bone Tumor Diagnosis and Treatments
- Salivary Gland Tumors Diagnosis and Treatment
- Hedgehog Signaling Pathway Studies
- Dental Trauma and Treatments
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Cleft Lip and Palate Research
- Dental Erosion and Treatment
University of Campania "Luigi Vanvitelli"
2014-2025
University of Catania
2025
Carlo Forlanini Hospital
2014-2024
Azienda Ospedaliera San Camillo-Forlanini
2022
University of Naples Federico II
2007-2021
Azienda Ospedaliera Universitaria Università degli Studi della Campania Luigi Vanvitelli
2021
University of Messina
2015-2020
Nini Hospital
2014-2019
Laboratoire de Génétique Médicale
2019
University of Foggia
2014-2018
In this study we used a biocomplex constructed from dental pulp stem/progenitor cells (DPCs) and collagen sponge scaffold for oro-maxillo-facial (OMF) bone tissue repair in patients requiring extraction of their third molars.The experiments were carried out according to our Internal Ethical Committee Guidelines written informed consent was obtained the patients.The presented with bilateral reabsorption alveolar ridge distal second molar secondary impaction on cortical lamina, producing...
Curcumin (diferuloylmethane) is a polyphenol derived from the Curcuma longa plant. has been used extensively in Ayurvedic medicine, as it nontoxic and exhibits variety of therapeutic properties, including antioxidant, analgesic, anti‑inflammatory antiseptic activities. Recently, certain studies have indicated that curcumin may exert anticancer effects biological pathways involved mutagenesis, apoptosis, tumorigenesis, cell cycle regulation metastasis. The present study reviewed previous...
Abstract Mesenchymal stem cells deriving from dental pulp differentiate into osteoblasts capable of producing bone. In previous studies, we extensively demonstrated that, when seeded on collagen I scaffolds, these can be conveniently used for the repair human mandible defects. Here, assess stability and quality regenerated bone vessel network 3 years after grafting intervention, with conventional procedures in-line holotomography, an advanced phase-imaging method using synchrotron radiation...
Dental pulp stem cells (DPSCs) can be found within the "cell rich zone" of dental pulp. Their embryonic origin, from neural crests, explains their multipotency. Up to now, two groups have studied these extensively, albeit with different results. One group claims that produce a "dentin-like tissue", whereas other research has demonstrated are capable producing bone, both in vitro and vivo. In addition, it been reported easily cryopreserved stored for long periods time still retain...
Adult mesenchymal stem cells, such as dental pulp are of great interest for cell-based tissue engineering strategies because they can differentiate into a variety tissue-specific above all, osteoblasts. In recent years, epigenetic studies on cells have indicated that specific histone alterations and modifying enzymes play essential roles in cell differentiation. However, although several reported valproic acid (VPA)-a selective inhibitor deacetylases (HDAC)-enhances osteoblast...
The aim of the present study is to compare histological aspects bone formation in atrophic posterior mandibles augmented by autologous block from chin area with corticocancellous allograft used as inlays sandwich technique. Materials and Methods . Sixteen patients bilateral partial edentulism mandible were selected. residual height, preliminarily measured computed tomography scans, ranged between 5 7 mm inferior alveolar nerve. All required regeneration procedure (control group) versus Puros...
Abstract The aim of this randomized controlled trial was to evaluate the survival rate, marginal bone level, and aesthetic outcome; at 3 years’ follow-up, dental implants placed into a high-esthetic zone by comparing 2 techniques postextraction implant with immediate loading: socket shied technique conventional insertion technique. Several clinical studies suggested that avulsion element causes dimensional alterations both soft hard tissues postextractive site. To increase outcomes,...
The accuracy of surgical guides is a relevant factor in both safety and prosthetic implications. impact widespread fabrication technologies (milling 3D printing) was investigated.Surgical manufactured by means two specific milling 3D-printing systems were digitized compared analysis with the digital file designed guides. surface mean distance (at where teeth mucosa made contact) axial linear deviations sleeves' housings measured metrological software program. Univariate multivariate...
Dental pulp stem cells (DPSCs) are multipotent derived from neural crest and mesenchyme have the capacity to differentiate into multiple cell lineages.It has already been demonstrated that DPSCs melanocyte-like but only when cultivated in a specific melanocyte differentiating medium.In this study we shown, for first time, capable of spontaneously mature melanocytes, which display molecular ultrastructural features full development, including expression markers presence melanosomes up...
ABSTRACT Background: An adequate alveolar crest is essential for implant placement in terms of esthetics and function. The objective this randomized clinical trial was to compare the preservation ridge dimensions following tooth extraction using porcine‐derived xenograft combined with a membrane versus extraction‐alone (EXT) sites. Methods: Fifteen patients who required double contralateral premolars delayed were randomly selected receive both ridge‐preservation procedure EXT. test sites...
Human dental pulp stem cells (hDPSCs) are mesenchymal that have been successfully used in human bone tissue engineering. To establish whether these can lead to a ready be grafted, we checked DPSCs for their osteogenic and angiogenic differentiation capabilities with the specific aim of obtaining new tool transplantation. Therefore, hDPSCs were specifically selected from stromal-vascular fraction, using appropriate markers, cultured. Growth curves, expression bone-related calcification...
To describe the early healing events in alveolar socket during first 8 weeks of spontaneous after tooth extraction.16 adult beagle dogs were selected and five periods analysed (4 h, 1 week, 2 weeks, 4 weeks). Mandibular premolars extracted each corresponding to mesial root was left heal undisturbed. In period, three animals euthanatized, providing four study sites. Healing assessed by descriptive histology histometric analysis using as landmarks: vertical distance between buccal lingual...