A5101650950- Viral gastroenteritis research and epidemiology
- Bacteriophages and microbial interactions
- SARS-CoV-2 and COVID-19 Research
- Zoonotic diseases and public health
- Retinal Diseases and Treatments
- Gut microbiota and health
- Microbial infections and disease research
- Genetic Mapping and Diversity in Plants and Animals
- Ophthalmology and Visual Impairment Studies
- Aquaculture disease management and microbiota
- Genetic diversity and population structure
- Probiotics and Fermented Foods
- Animal Virus Infections Studies
- Plant Virus Research Studies
- Plant and Fungal Interactions Research
- Genomics and Phylogenetic Studies
- Corneal surgery and disorders
- vaccines and immunoinformatics approaches
BGI Group (China)
2015-2024
BGI Genomics
2023
Sichuan University
2020
High-resolution genetic maps are essential for fine mapping of complex traits, genome assembly, and comparative genomic analysis. Single-nucleotide polymorphisms (SNPs) the primary molecular markers used map construction. In this study, we identified 13,362 SNPs evenly distributed across Japanese flounder (Paralichthys olivaceus) genome. Of these SNPs, 12,712 high-confidence were subjected to high-throughput genotyping assigned 24 consensus linkage groups (LGs). The total length was 3,497.29...
Pasteurella multocida is a leading cause of respiratory diseases in many host species. To understand the genetic characteristics P. strains isolated from different species, we sequenced genomic DNA pigs and analyzed avian bovine pigs, rabbits using whole genome sequence (WGS) data. Our results found that capsular: lipopolysaccharide (LPS): multilocus typing (MLST) genotype A: L1: ST129 (43.75%) was predominant multocida; while genotypes B: L2: ST122 (60.00%) L3: ST79 (30.00%) were...
Abstract Background The prevalence of myopia and associated risk factors among children in Chongqing has not yet been determined. This study investigated the possible relationships between several related school Chongqing. Methods cross-sectional assessed a sample 997 (7–13 years age) attending primary Data were obtained from visual acuity refractive error measurements structured questionnaire. Myopia was defined as < 5.0 (spherical equivalent) − 0.50 diopters (D) either eye. Multilevel...
The objective of this study was to determine whether a new combination immunogens could be more effective than the S–2P design in terms eliciting an immune response. aimed use unified formulation standard make comparison between immunogen design. analyzed published mutation strategies known COVID-19 vaccines and also Spike protein variants RCSB database identify most promising combination. By choosing different variants, we prepared well characterized mRNA preparations administered them...
Metagenomic sequencing (mNGS) is a powerful diagnostic tool to detect causative pathogens in clinical microbiological testing owing its unbiasedness and substantially reduced costs. Rapid accurate classification of metagenomic sequences critical procedure for pathogen identification dry-lab step mNGS test. However, practices the technology are hampered by challenge classifying within clinically relevant timeframe. Here, we present GPMeta, novel GPU-accelerated approach ultrarapid from...
To analyze the distribution and pulsed field gel electrophoresis (PFGE) patterns of five kinds diarrheagenic Escherichia coli (DEC) in infected diarrhea population Henan province 2013.Gathering 1 037 strains E. patients from four sentinel hospitals multi-pathogen monitoring system 2013. Stool samples were cultured with Mac agar plates using KIA/MIU biochemical action as preliminary method to identify strains; preparation DNA template thermal cracking multiplex PCR detect DEC. According...