A5045115239- MicroRNA in disease regulation
- Circular RNAs in diseases
- Advanced Neuroimaging Techniques and Applications
- Extracellular vesicles in disease
- Genetic Syndromes and Imprinting
- Ubiquitin and proteasome pathways
- Kruppel-like factors research
- Total Knee Arthroplasty Outcomes
- Glioma Diagnosis and Treatment
- Neurological and metabolic disorders
- Animal Genetics and Reproduction
- Glycosylation and Glycoproteins Research
- Advanced MRI Techniques and Applications
- Sulfur Compounds in Biology
- Lipid metabolism and disorders
- Radiomics and Machine Learning in Medical Imaging
- Hip and Femur Fractures
- Sinusitis and nasal conditions
- Animal Nutrition and Physiology
- Antimicrobial Peptides and Activities
- Orthopaedic implants and arthroplasty
- Heavy Metal Exposure and Toxicity
- Proteins in Food Systems
Shihezi University
2023-2024
University of Cambridge
2019
Second Hospital of Shandong University
2018
Chinese Academy of Medical Sciences & Peking Union Medical College
2016
Peking Union Medical College Hospital
2016
Dalian Medical University
2013
Northwest A&F University
2012
University of California, Davis
1995
Abstract The Arabidopsis thaliana ecotype Columbia ubiquitin gene family consists of 14 members that can be divided into three types genes; polyubiquitin genes, ubiquitin-like genes and extension genes. isolation characterization eight sequences, consisting four are described here, their relationships to each other previously identified were analyzed. UBQ3, UBQ10, UBQ11 UBQ14, contain tandem repeats the 228-bp coding region. Together with a gene, UBQ4, they differ in synonymous...
The release of adipose tissue-derived miRNAs is increased under conditions obesity, but the exact molecular mechanisms involved have not been elucidated. This study investigated whether obesity-induced increases in palmitic acid (PA) content could activate NF-κB/endoplasmic reticulum stress (ER stress) pathway and promote expression exosomal adipocytes.
ABSTRACT Aims/introduction Previous studies have found that miR‐4472 is overexpressed in the serum of individuals with obesity and type 2 diabetes mellitus (T2DM), which may participate process obesity‐induced T2DM. However, a role for has not been demonstrated. Here, we aim to investigate whether increased content adipose tissue derived from exosomes inhibits glucose uptake skeletal muscle by downregulating expression its target gene. Materials methods In vitro C2C12 3T3‐L1 cells, vivo...
Abstract In the obesity context, inflammatory cytokines secreted by adipocytes lead to insulin resistance and are key metabolic syndrome development. our previous study, we found that transcription factor KLF7 promoted expression of p‐p65 IL‐6 in adipocytes. However, specific molecular mechanism remained unclear. present KLF7, PKCζ, p‐IκB, p‐p65, epididymal white adipose tissue (Epi WAT) mice fed a high‐fat diet (HFD) was significantly increased. contrast, decreased Epi WAT fat conditional...
<h3>BACKGROUND AND PURPOSE:</h3> Previous studies by using proton MR spectroscopy found metabolite abnormalities in the cerebral cortex and white matter of patients with type 2 diabetes mellitus. The present study was undertaken to detect differences lenticular nuclei thalamus T2DM. <h3>MATERIALS METHODS:</h3> Twenty subjects T2DM 22 age-matched control underwent single-voxel left right thalami. NAA/Cr Cho/Cr ratios were calculated. Brain lactic acid, fasting blood glucose, glycosylated...
To investigate the molecular mechanism by which diets of different energy levels alter fat accumulation, 120 Black-Bone chickens were divided into 3 groups and fed with varying for six weeks (low: 3.02 Mcal/kg, moderate: 3.22 high: 3.42 Mcal/kg).The high-energy diet increased concentration blood lipids.Furthermore, intake inhibited activities several serum lipases.Histological sections showed over-synthesis lipids in livers diets.Data from western blotting PCR analyses indicated that key...
Gene polymorphism is an important factor that affects human susceptibility to toxin. For example, previous studies suggested ALAD genotype affect workers lead toxic effects, including hemopoiesis, nerve system. However, we have few researches in Taiwan, though there are thousands of involved lead-related industries. On the other hand, although it well known deposits bone mineral component and interaction with calcium, were on relation lead, calcium (or density) vitamin D receptor genes when...