The effect of 3 months low dose (120 micrograms/kg.week or 0.24 IU/kg.week) recombinant human GH (rhGH) treatment on glucose tolerance, insulin secretion, and insulin- glucose-mediated disposal was examined in 10 GH-deficient adults. frequently sampled iv tolerance test performed at baseline after 1 week rhGH therapy analyzed by the minimal model method Bergman to provide estimates decay rate, first second phase secretion (phi phi 2), fractional clearance insulin, insulin-mediated disposal....

20 normoglycemic first degree relatives of non-insulin-dependent diabetes mellitus (NIDDM) patients were compared with matched subjects without any family history using the intravenous glucose tolerance test minimal model analysis disappearance and insulin kinetics. Intravenous index (Kg) was similar in both groups (1.60 +/- 0.14 vs 1.59 0.18, x 10(-2) min-1, NS). However, sensitivity (Si) reduced (3.49 0.43 4.80 0.61, 10(-4) min-1 per mU/liter, P = 0.05), whereas effectiveness (Sg)...

past year.In four cases bone-marrow suppression was limited to the myeloid compartment,'-4 whereas in present case, as one reported by Gavras et al,5 erythroid and megakaryocytic cell lines were all suppressed.In cases, ours, patients had renal insufficiency.Since captopril is eliminated kidney, toxic concentrations of drug may have developed.Other drugs given three including immunosuppressives one, patient suspected having underlying blood dyscrasia,4 but our no disease combined...

Reduced glucose effectiveness is a predictor of future tolerance in individuals with family history type 2 diabetes. We examined retrospectively at 10 years normoglycemic relatives diabetic subjects (RELs) the pathophysiological role development isolated impaired fasting glucose, intolerance, and acute insulin release. At 0 years, 19 RELs 18 matched control had (GE), sensitivity, release (AIR)IVGTT, disposition index measured during an iv test (IVGTT), using minimal model analysis. oral...

Increasing the K intake of rats above requirements reduced half-retention time for 134Cs but at a decreasing rate. Maximum was 5% which resulted in T1/2 6 days. The Na added 0.3 or 2% to high diet had no influence on 134Cs. Rb salts retention would indicate that this ion is less effective than K. decreased effect may be due its failure adequately substitute normal muscle cell metabolism.

The day-to-day variability of blood glucose concentrations in juvenile diabetes means that it is often more reasonable to aim achieve a generally good pattern control, rather than regularly assess the next insulin dose after each measurement. This immediate assessment by patient his not always necessary. We have investigated control 22 insulin-requiring diabetic patients monthly series four samples taken during day into collector bottles and transported laboratory for assay. overall before...

A study of transfer to milk three isotopes Tc indicated different results for 99mTcO4−, 95mTcO4−, and 99TcO4−. When the were given orally lactating goats in separate experiments, coefficients increased with decreasing specific activity. Gut absorption administered as pertechnetate (TcO4−) was decreased by reduction TcO4− rumen. The rate rumen greater higher activity doses Tc. These suggest that a radioisotope may significantly influence estimated dose humans from contaminated and, probably,...

THE action of rubidium (Rb) on frog heart muscle was shown by Ringer (1884) to be similar that potassium (K). Loeb (1920) reported both Rb and cesium would replace K in solutions for the development sea urchin eggs. Lazritzke Szorenyi (1934) have yeast can utilize place K. Mitchell et al. (1921) hyperirritability death after two three weeks substituting diets rats. Heppel Schmidt (1938) concluded a short time Follis (1943) observed rats K-deficient showed improved growth when 0.5 % chloride...

Context Historically, medical school curriculums have not addressed applications of nutrition therapy (MNT) in patient care plans. In 2020, an elective pilot lifestyle medicine course, “Food and Nutrition as Medicine (FANAM),” was implemented at Edward Via College Osteopathic Carolinas (VCOM-Carolinas) using a community-centric model. Objective Teach students skills education, culinary techniques, patient-centered through intersectional lenses culture, available resources, health literacy....

HbA 1c values in capillary blood (50 μl) were compared with venous samples, assayed by HPLC (normal < 6.6%) 64 Type 1 and 2 diabetic patients. One group (n = 43) collected the Outpatient Department simultaneously a sample. The sample collection was not supervised. A second 21) obtained two samples during routine home glucose monitoring Unistep containers within days of posted them to laboratory questionnaire about ease use acceptance method. In group, 97% returned there no postal losses,...