A5022782652- Surface Roughness and Optical Measurements
- Ferroptosis and cancer prognosis
- Autophagy in Disease and Therapy
- Advanced Measurement and Detection Methods
- Heme Oxygenase-1 and Carbon Monoxide
- Advanced Fiber Optic Sensors
PLA Army Engineering University
2022
Jinan University
2022
Phospholipid peroxidation of polyunsaturated fatty acids at the bis-allylic position drives ferroptosis. Here we identify a novel role for phospholipid in inhibition autophagy. Using vitro and vivo models, report that induced by glutathione peroxidase-4 arachidonate 15-lipoxygenase overexpression leads to overload peroxidized phospholipids culminate Functional lipidomics analysis further demonstrated autophagy was associated with an increase phosphatidylethanolamine (PE) conjugated LC3. We...
Molecularly defined cortical cell types have recently been linked to whole neuronal morphology (WNM), particularly those characterized by whole-brain-wide projections, such as intratelencephalic (IT), extratelencephalic (ET), and corticothalamic (CT) neurons. In contrast, classical morphological classifications (e.g., tufted TPC, small SPC, stellate SSC) are based primarily on local dendrosomatic axonal structures, especially apical dendrites. This study bridges these perspectives...