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Contact & Profiles
A5093068124
Research Areas
- Cancer-related Molecular Pathways
- Autophagy in Disease and Therapy
- Ubiquitin and proteasome pathways
Vilnius University
2023
Abstract The protein sequestosome 1 (p62/SQSTM1) is primarily known as a selective autophagy cargo receptor, but due to its multidomain structure, it also has roles in the ubiquitin‐proteasome system, metabolism, cell death and survival signalling. increase p62 levels detected some types of cancers, including colorectal cancer (CRC). Chemoresistance main cause high mortality rates CRC patients. Since can regulate both death, potential modulator chemoresistance. impact on molecular causes...
10.1002/jcb.30488
article
EN
Journal of Cellular Biochemistry
2023-10-16
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