- Aquaculture disease management and microbiota
- Aquaculture Nutrition and Growth
- Vibrio bacteria research studies
- Environmental Toxicology and Ecotoxicology
- Computational Drug Discovery Methods
- Nanoparticles: synthesis and applications
- Cholinesterase and Neurodegenerative Diseases
- Invertebrate Immune Response Mechanisms
- Aquatic life and conservation
- Antifungal resistance and susceptibility
- Moringa oleifera research and applications
- Parasite Biology and Host Interactions
- Identification and Quantification in Food
- Pharmaceutical and Antibiotic Environmental Impacts
- Animal Nutrition and Physiology
- Probiotics and Fermented Foods
- Natural Antidiabetic Agents Studies
- Pharmacogenetics and Drug Metabolism
- Reproductive tract infections research
- Phytochemistry and Bioactivity Studies
- Ginger and Zingiberaceae research
- Biopolymer Synthesis and Applications
- Phytochemicals and Medicinal Plants
- Clostridium difficile and Clostridium perfringens research
- Protein Hydrolysis and Bioactive Peptides
Central Institute of Fisheries Education
2011-2025
All India Institute of Medical Sciences
2023
Indian Institute of Science Education and Research, Bhopal
2017-2019
Jamia Millia Islamia
2014-2016
Aquatic Systems (United States)
2014
Background: Copper nanoparticles (CuONPs) have garnered significant attention for their unique properties and potential applications in agriculture, medicine, environmental science. Using eco-friendly methods, the stem extract of Tinospora cordifolia, a medicinal plant known its bioactive compounds, can act as reducing agent CuONP synthesis. This approach minimises impact while leveraging plant’s inherent properties. Aim: To synthesise characterise CuONPs using T. cordifolia evaluate...
Ectoparasites are a serious concern for the ornamental fish industry, causing severe pathological and behavioral changes that diminish aesthetic value of adversely affect trade. Recently, phytotherapy, application plant extracts or their active biomolecules, has gained attention control treatment various diseases humans animals, including fish. The present study evaluated broad-spectrum antiparasitic activity azadirachtin, neem-based bioactive molecule, under in vitro condition against adult...
Candida dubliniensis is an emerging pathogenic yeast in humans and infections are usually restricted to mucosal parts of the body. However, its presence specimens immunocompromised individuals, especially HIV-positive patients, major medical concern. There a large fraction genomes C. database which uncharacterized for their biochemical, biophysical, and/or cellular functions, identified as hypothetical proteins (HPs). Function annotation genome is, therefore, essentially required facilitate...
The recent advances in microbiome studies have revealed the role of gut microbiota altering pharmacological properties oral drugs, which contributes to patient-response variation and undesired effect drug molecule. These are essential guide us for achieving desired efficacy activity existing molecule or discovering novel more effective therapeutics. However, one main limitations is lack atomistic details on binding metabolism these molecules by gut-microbial enzymes. Therefore, this study, a...
Background: Carbonic anhydrase IX (CAIX) is an attractive target for anticancer therapy because it selectively overexpressed in tumor cells.Various CAs' inhibitors (sulfonamides/sulfaumates and coumarins) are reported as promising anti-cancer agents, showed appreciable affinity selectivity.Novel chemical scaffolds with improved pharmacological properties essential the development of safe potent CAIX inhibitors.Materials methods: Crystal structure its revealed critical residues that interacts...
The study was performed over a period of 60 days to evaluate the effect dietary carrageenan on growth, hematology, biochemistry, and innate immunity in rohu Labeo rohita. A basal diet supplemented with iota (i)Carrageenan at 5, 10 20g/kg fed three different groups fish for days. were examined 15, 30, 45, after commencement study. Parameters growth (absolute specific rate, percentage weight gain), hematology (total erythrocyte count, total leucocyte thrombocyte count hemoglobin value),...
The present study was conducted to investigate the bacterial pathogens involved in mortality of cultured Pangasianodon hypophthalmus. Diseased fish samples were collected from Maharashtra, India for isolation pathogenic bacteria. isolates identified using 16S rRNA gene sequencing analysis which revealed that they 99% identical with Aeromonas jandaei. further characterized biochemical methods. lowest dose caused 50% cumulative (LD50) hypophthalmus 8.84 X 105 CFU per fish. This achieved by...
The human gut harbors diverse bacterial species in the gut, which play an important role metabolism of food and host health. Recent studies have also revealed their altering pharmacological properties efficacy oral drugs through promiscuous metabolism. However, atomistic details enzyme-drug interactions enzymes can potentially carry out drug molecules are still scarce. A well-known example is FDA amphetamine (a central nervous system stimulant), has been predicted to undergo by bacteria....
Interpretation :To investigate the acute inflammatory response in induced by carrageenan (red seaweeds)The fingerlings were injected with 50 examined at 3, 6, 12, 24, 48 and 96 hr post injection.The cellular markers that includes thrombocyte, macrophage, monocyte, granulocyte (neutrophils) lymphocyte counts, serum myeloperoxidase activity, nitroblue tetrazolium (NBT) assay, total protein, albumin globulin, C-reactive protein (CRP) cortisol examined.Additionally, mRNA expression of...