Xiaodong Han

ORCID: 0009-0005-7682-9282
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About
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Research Areas
  • Nanoparticles: synthesis and applications
  • Inhalation and Respiratory Drug Delivery
  • Chemokine receptors and signaling
  • MicroRNA in disease regulation
  • Graphene and Nanomaterials Applications
  • Immunotherapy and Immune Responses
  • Cancer Immunotherapy and Biomarkers
  • Microplastics and Plastic Pollution
  • Allergic Rhinitis and Sensitization
  • Toxin Mechanisms and Immunotoxins
  • Asthma and respiratory diseases
  • Pharmaceutical studies and practices
  • Retinal Diseases and Treatments
  • Circular RNAs in diseases
  • Cancer-related molecular mechanisms research
  • Ocular Diseases and Behçet’s Syndrome
  • Phytochemicals and Medicinal Plants
  • Retinal and Optic Conditions

Nanjing University
2023-2024

People's Hospital of Cangzhou
2019

People 's Hospital of Jilin Province
2017

Hebei Medical University
2016

MicroRNAs (miRNAs) are small non-coding RNAs that key post-transcriptional regulators of gene expression. MicroRNA-214 (miR-214) and microRNA-218 (miR-218) have shown the function tumor suppressors in various types human cancers. However, biological functions miR-214 miR-218 breast cancer not been elucidated completely. The present study evaluated expression cancer. Our results revealed were significantly decreased tissues compared with adjacent tissues. aberrant negatively associated Ki-67,...

10.3892/or.2016.4749 article EN cc-by-nc-nd Oncology Reports 2016-04-15

Gold nanoparticles (AuNPs) is the most excellent anticancer theranostic synthesized through efficient, simple and green synthesis method using extracts of Trichosanthes kirilowii, extensively characterized by UV-spectroscopy, FT-IR TEM techniques. The AuNPs, means T. kirilowii identified that were ∼50 nm in size, which an admirable nano dimension attained synthesis. In agreement with outcome microscopic cellular morphological observations, MTT assay showed effective, selective,...

10.1080/21691401.2019.1626412 article EN cc-by Artificial Cells Nanomedicine and Biotechnology 2019-08-28

Nanoplastics (NPs), regarded as the emerging contaminants, can enter and be mostly accumulated in digest tract, which pose potential threat to intestinal health. In this study, mice were orally exposed polystyrene (PS), PS-COOH PS-NH2 NPs with size of 100 nm at a human equivalent dose for 28 consecutive days. All three kinds PS-NPs triggered Crohn’s ileitis-like features, such ileum structure impairment, increased proinflammatory cytokines epithelial cell (IEC) necroptosis, PS-COOH/PS-NH2...

10.2139/ssrn.4382811 article EN 2023-01-01
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