A5065907526- Medicinal Plants and Bioactive Compounds
- Zoonotic diseases and public health
- Vector-borne infectious diseases
- Neurological Disease Mechanisms and Treatments
- Alzheimer's disease research and treatments
- Neuroinflammation and Neurodegeneration Mechanisms
- Leptospirosis research and findings
- Saffron Plant Research Studies
- Phytochemistry and Biological Activities
- Plant Stress Responses and Tolerance
- Hearing, Cochlea, Tinnitus, Genetics
- Sperm and Testicular Function
- Yersinia bacterium, plague, ectoparasites research
- Glaucoma and retinal disorders
- Intensive Care Unit Cognitive Disorders
- Ion Channels and Receptors
- Mitochondrial Function and Pathology
- Genetics, Aging, and Longevity in Model Organisms
- Vestibular and auditory disorders
- Rabbits: Nutrition, Reproduction, Health
- Tryptophan and brain disorders
- S100 Proteins and Annexins
- Flavonoids in Medical Research
- Neurological Disorders and Treatments
- Neurobiology and Insect Physiology Research
University of Catania
2018-2023
University of Pavia
2014
Background An increase in the frequency of circulating endothelial colony forming cells (ECFCs), only subset progenitor (EPCs) truly belonging to phenotype, occurs patients affected by primary myelofibrosis (PMF). Herein, they might contribute enhanced neovascularisation fibrotic bone marrow and spleen. Store-operated Ca2+ entry (SOCE) activated depletion inositol-1,4,5-trisphosphate (InsP3)-sensitive store drives proliferation ECFCs isolated from both healthy donors (N-ECFCs) subjects...
Background: Meniere's disease (MD) is a cochlear neurodegenerative disease. Hearing loss appears to be triggered by oxidative stress in the ganglion neurons of inner ear. Objective: Here, we confirm variation markers and inflammation patients with Meniere hypothesize that chronic treatment Coriolus mushroom helps response acts on α-synuclein NF-kB-mediated inflammatory processes. Methods: Markers were evaluated MD or without for 3 6 months. Results: had small increase Nrf2, HO-1, γ-GC,...
The aim of this study was to assess the beneficial effects oral supplementation Lepidium meyenii (Maca) on improving and keeping sperm quality in dogs during storage, investigate its effect changes testosterone concentrations. Forty male were enrolled divided into four groups ten each: two subfertile (control treatment) normofertile groups. treatment received Maca a capsule formulation (75 mg/kg), while control placebo. spermiogram levels assessed at three times cycle: 0 (T0), 31 (T31), 62...
Bacterial sepsis induces the production of excessive pro-inflammatory cytokines and oxidative stress, resulting in tissue injury hyperinflammation. Patients recovering from have increased rates central nervous system (CNS) morbidities, which are linked to long-term cognitive impairment, such as neurodegenerative pathologies. This paper focuses on hyperinflammation observed acute phase development neuroinflammation associated with septicemia. Here we evaluate effects Coriolus versicolor...
Alzheimer’s disease (AD) is the most common cause of dementia, and its prevalence rises with age. Inflammation altered antioxidant systems play essential roles in genesis neurodegenerative diseases. In this work, we looked at effects MemophenolTM, a compound rich polyphenols derived from French grape (Vitis vinifera L.) wild North American blueberry (Vaccinium angustifolium A.) extracts, rat model AD. Methods: For 60 days, animals were administered AlCl3 (100 mg/kg, orally) D-galactose (60...
Dogs are considered the main reservoir of several zoonoses endemic to Mediterranean Basin. In this study, a prevalence infections and coinfections canine vector-borne diseases was analyzed in apparently healthy dogs different pure breeds Sicily (Italy), where these endemic. The seroprevalence Leishmania infantum, Ricketsia ricketsii, Anaplasma phagocytophilum, Erlichia canis assessed, as single coinfections. Biochemical hematological parameters were evaluated, epidemiological factors,...
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Determining the boundaries of norm and pathology mental aging is an urgent scientific task. We have formulated a hypothesis about presence transitional period within cognitive continuum, which represents borderline between normality disorder; such state subjective decline. The outcome this depends on interaction disease factors protective factors, one reserve. review to systematize current data in field research decline that prevent its transformation into disorder. A systematic studies was...
Vector-borne infectious zoonotic diseases are relevant problem, not only in veterinary medicine, as well human medicine. Dogs considered the main reservoir of these zoonosis, and sentinels for control that, due to increase temperatures climate change, becoming more frequent. Prevalence infections coinfections canine vector-borne has been analyzed apparently healthy dogs breeds St. Bernard, English Cocker Spaniel, Setter, Cirneco dell'Etna crossbred Sicily (Italy), where endemics....