- Meat and Animal Product Quality
- French Urban and Social Studies
- Muscle metabolism and nutrition
- Protein Hydrolysis and Bioactive Peptides
- Archaeological and Geological Studies
- Calpain Protease Function and Regulation
- Biochemical effects in animals
- Animal Nutrition and Physiology
- Ubiquitin and proteasome pathways
- Proteins in Food Systems
- Archaeology and ancient environmental studies
- Bee Products Chemical Analysis
- Ancient and Medieval Archaeology Studies
- Nutrition and Health in Aging
- Maritime and Coastal Archaeology
- T-cell and Retrovirus Studies
- Environmental and Cultural Studies in Latin America and Beyond
- Geology and Paleoclimatology Research
- Identification and Quantification in Food
- Protease and Inhibitor Mechanisms
- Pleistocene-Era Hominins and Archaeology
- Pharmacological Effects and Assays
- Child Nutrition and Water Access
- Digestive system and related health
- Glycosylation and Glycoproteins Research
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2020-2024
Institut National de Recherches Archéologiques Préventives
2007-2024
Centre National de la Recherche Scientifique
2021-2023
Laboratoire Animal et Agroécosystèmes
2010-2022
DuPont (France)
2016
Banque de France
2012
Institut National de la Recherche Agronomique
2002-2010
Terra Nova Learning Systems (United States)
2009
Laboratoire de Biochimie
2005
Université Paris Cité
2001
The present study aimed to evaluate the digestion rate and nutritional quality of pig muscle proteins in relation different meat processes (aging, mincing, cooking). Under our experimental conditions, aging mincing had little impact on protein digestion. Heat treatments temperature-dependent effects degradation potential. At 70 °C, underwent denaturation that enhanced speed pepsin by increasing enzyme accessibility cleavage sites. Above 100 oxidation-related aggregation slowed but improved...
The objective of this study was to investigate the effect chemical oxidation on myofibrillar protein digestibility. Myofibrils were prepared from pig M. longissimus dorsi and oxidized by a hydroxyl radical generating system. Oxidative modifications proteins assessed carbonyl content, surface hydrophobicity, electrophoresis, immunoblotting. Oxidized or nonoxidized then exposed proteases digestive tract (pepsin, trypsin, alpha-chymotrypsin). Results showed direct quantitative relationship...
BACKGROUND Proteasomes are nonlysosomal proteolytic structures that have been implicated in cell growth and differentiation. Abnormal expression levels of proteasomes described tumor cells, can be detected measured plasma. The objective this study was to characterize differences proteasome between normal, healthy donors patients with neoplastic disease correlate the findings clinical status other biologic markers spread. METHODS Plasma were using a sandwich enzyme-linked immunosorbent assay...
Calpain 1, a ubiquitous calcium‐dependent intracellular protease, was recently found in tight association with myofibrils skeletal muscle tissue [Delgado EF, Geesink GH, Marchello JA, Goll DE & Koohmaraie M (2001) J Anim Sci 79 , 2097–2107). Our immunofluorescence and immunoelectron microscopy investigations restrain the protease location at periphery of Z‐band midpoint I‐band. Furthermore, calpain 1 is to localize myofibril fractures, described as proteolysis sites, postmortem bovine...
Collagen antioxidant peptides are being widely studied. However, no research has paid attention to biological parameters such as the age and anatomy of collagen-rich tissues, which can determine a change in tissue structure composition, then bioactivity. Moreover, only few works have studied assessed activity on food matrix. This work aimed investigate effect bovine’s bone anatomy, six different enzymes, collagen peptides. was extracted from young old bovine femur tibia; enzymes were used...
In vitro digestions of dry-cured sausages formulated with four different rates added sodium nitrite and nitrate (NaNO2 / NaNO3, in ppm: 0/0; 80/80; 120/120; 0/200) were performed a dynamic gastrointestinal digester (DIDGI®). The chemical reactivity the potentially toxic nitroso-compounds (NOCs), oxidation reactions products iron types evaluated over time. No nor dose effect was observed on NOCs' reactivity. Nitrosothiols scarce, nitrosylheme destabilized for every conditions, possibly...
ABSTRACTIn Central America, maize processing for the production of tortillas bears a strong cultural connotation preservation traditions. The METATE project aims to explore long-term history, from Prehispanic times until today, and use grinding stone tools (metates molcajetes) on slopes El Metate volcano (Michoacán, Mexico). It has been approached through multidisciplinary program including volcanology, archaeology, anthropology. village Turícuaro recognized centuries as major center metate...
Nutritional strategies are required to limit the prevalence of denutrition in elderly.