A5094580453- Glycosylation and Glycoproteins Research
- Protein purification and stability
- Monoclonal and Polyclonal Antibodies Research
Robert Koch Institute
2024-2025
Staphylococcal enterotoxins (SEs) are major contributors to foodborne intoxications. Reliable detection methods for SEs essential maintain food safety and protect public health. Since the heat-stable toxins also exert their toxic effect in absence of bacterium, reliance on DNA alone can be misleading: it does not allow determining which specific encoded by a given strain produced epidemiologically linked with outbreak. Commercially available diagnostic assays SE so far limited sensitivity...
Because of their superior properties for certain biological applications small antibody derivatives like fragment antigen binding (Fab) have found widespread use in basic research and as therapeutics. However, generation Fab-fragments is still a rather complex matter, reflected by the fact that variety methods purification techniques are necessary production all different classes (kappa/lambda light chains, type species). Here we demonstrate derived from six antibodies human or murine origin...