A5100427052- Gastric Cancer Management and Outcomes
- Liver Disease Diagnosis and Treatment
- Metastasis and carcinoma case studies
- Cardiac Imaging and Diagnostics
- Renal cell carcinoma treatment
- Cardiovascular Disease and Adiposity
- Ferroptosis and cancer prognosis
- Systemic Lupus Erythematosus Research
- Cerebrovascular and Carotid Artery Diseases
- Cancer Mechanisms and Therapy
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Alcohol Consumption and Health Effects
- Inflammatory Myopathies and Dermatomyositis
- Gastrointestinal Tumor Research and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Digital Radiography and Breast Imaging
- Radiomics and Machine Learning in Medical Imaging
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Esophageal Cancer Research and Treatment
- Gout, Hyperuricemia, Uric Acid
- AI in cancer detection
- Sarcoidosis and Beryllium Toxicity Research
- Bladder and Urothelial Cancer Treatments
- Cardiovascular Health and Disease Prevention
- Liver Disease and Transplantation
Chinese Academy of Medical Sciences & Peking Union Medical College
2023-2025
Shanxi Medical University
2022-2025
Yangzhou University
2023-2025
First Affiliated Hospital of Anhui Medical University
2025
Anhui Medical University
2015-2025
Guangxi Medical University
2025
National Clinical Research
2024
Children's Hospital of Fudan University
2021-2024
Affiliated Hospital of Nantong University
2024
Nantong University
2024
Purpose To investigate the utility of a liposomal-iodinated nanoparticle contrast agent and computed tomography (CT) imaging for characterization primary nodules in genetically engineered mouse models non-small cell lung cancer. Methods Primary cancers with mutations K-ras alone (KrasLA1) or combination p53 (LSL-KrasG12D;p53FL/FL) were generated. A liposomal-iodine containing 120 mg Iodine/mL was administered systemically at dose 16 µl/gm body weight. Longitudinal micro-CT cardio-respiratory...
Objectives The study aimed to describe the characteristics of gastrointestinal (GI) involvement in a cohort hospitalized children with IgA vasculitis (IgAV) China. Method We reviewed records IgAV patients from January 2014 December 2020 at one tertiary medical center. were divided into severe GI group and non-severe according presence massive bleeding complications. clinical manifestations, laboratory factors, treatment analyzed between two groups. Results A total 1,179 due IgAV. was noted...
Objective Metabolic dysfunction-associated fatty liver disease (MAFLD) and nephrolithiasis are two common metabolic diseases, but their relationship has not yet been thoroughly studied. Therefore, this study aimed to explore the association between MAFLD assess effect of on risk nephrolithiasis. Materials methods This cross-sectional included 96,767 adults from China. All participants underwent medical examinations, including physical history tests, laboratory tests. Based ultrasound...
To identify high-risk gastric carcinoma patients with concurrent vascular and neural invasion ("double invasion") who are at heightened risk of progression-free survival (PFS) decline, enabling personalized clinical management. In this multi-center retrospective study, 559 double underwent curative gastrectomy between May 2002 December 2020 were analyzed. Prognostic factors for PFS identified using Lasso-Cox regression. Model validation included internal bootstrapping, calibration plots,...
Background: Statin therapy is associated with an increased risk of new-onset diabetes (NOD), possibly due to a reduction in coenzyme Q10 (CoQ10) levels as result statin use. This study aimed investigate the relationship between exogenous CoQ10 supplementation and development NOD. Methods: included 4394 participants from National Health Nutrition Examination Survey (NHANES). Baseline characteristics were compared those without NOD CoQ10. Univariate logistic regression was performed identify...
Arterial stiffness is recognized as a new risk factor for stroke. However, the association between estimated pulse wave velocity (ePWV), well-established indirect measure of arterial and stroke among older adults, remains incompletely investigated. This study utilized data from 3 prospective, nationally representative cohorts: Health Retirement Study in United States, English Longitudinal Aging Kingdom, China China. ePWV was calculated based on age mean pressure. Cox proportional hazard...
Objective Serum uric acid (SUA), a non-protein antioxidant, exerts anti-inflammatory and antioxidative stress effects. This study aimed to investigate the association between SUA levels risk of benign prostatic hyperplasia (BPH). Methods cross-sectional included 48 653 adult men who underwent health checkups at Health Examination Center Affiliated Hospital Yangzhou University in 2022. Data on demographics, clinical history laboratory parameters were collected. Multivariable logistic...
Abstract Skeletal muscle and fat tissue show distinct pathophysiological roles pivotal functions. The culmination of wasting accumulation represents an opposite terminal each state. Specifically, this situation has been designated as sarcopenic obesity. However, obesity still lacks a unanimous definition, diagnostic criteria, generalized modalities for assessment in the context versatile liver diseases. Moreover, underpinning mechanisms by which combination abnormal skeletal leads to...
Objective To explore the efficacy of initial treatment newly diagnosed childhood-onset lupus nephritis (cLN) with combination belimumab and either cyclophosphamide, mycophenolate mofetil, tacrolimus or multitargeted therapy. Methods A historical control study was conducted on children aged 5–17 years cLN. All patients recruited met 2012 Systemic Lupus International Collaborating Clinics and/or 2019 European League Against Rheumatism/American College Rheumatology classification criteria for...
Abstract Objective This study aimed to establish novel nomograms that could be used predict the prognosis of gastric carcinoma patients who underwent D2 + total gastrectomy on overall survival (OS) and progression-free (PFS). Methods Lasso regression was employed construct nomograms. The internal validation process included bootstrapping, which test accuracy predictions. calibration curve then demonstrate consistency In addition, Harrell’s Concordance index (C-index) time-dependent receiver...
Hepatocellular carcinoma (HCC) is a malignancy with bleak prognosis. Although emerging research increasingly supports the involvement of chromatin regulators (CRs) in cancer development, CRs HCC patients have not received proportionate attention. This study aimed to investigate role and prognostic significance patients, providing new insights for clinical diagnosis treatment strategies. We analyzed 424 samples The Cancer Genome Atlas-Liver hepatocellular (TCGA-LIHC) data identify key CR...
Serum lycopene exhibits distinct associations with all-cause and cardiovascular mortality in populations or without obesity.
Renal cell carcinoma (RCC) originated from parenchyma and the majority of malignancies originating in renal pelvis are transitional (TCC). In present study, a rare case RCC growing into mimicking TCC medical imaging is reported. The preoperative differentiation between important order to identify type surgical treatment required: Nephrectomy or ureteronephrectomy. role ureteroscopy biopsy emphasized accurate diagnosis pelvic mass. Thus, study provided fundamental evidence for pathogenesis...
We sought to develop novel nomograms accurately predict overall survival (OS) of chemotherapy cycles <9 and ≥9 construct risk stratification differentiate low-risk high-risk two cohorts.Patients who underwent curative-intent resection for gastric cancer between January 2002 May 2020 at a single China institution were identified. Variables associated with OS recorded analyzed according multivariable Cox models. Nomograms predicting 3- 5-year built variables resulting from Discrimination...
The coagulation system is closely related to the physiological status and immune response of body. Recent years, studies focusing on association between abnormalities tumor progression have been widely reported. In clear cell renal carcinoma (ccRCC), poor prognosis often occurs in patients with venous thrombosis abnormalities, there a lack research fields. Significant differences function were also demonstrated our clinical sample high ccRCC stage or grade. Therefore, this study, we analyzed...