A5101675218- Heart Rate Variability and Autonomic Control
- Non-Invasive Vital Sign Monitoring
- Cardiovascular Health and Disease Prevention
- Hemodynamic Monitoring and Therapy
- Cancer Genomics and Diagnostics
- Ferroptosis and cancer prognosis
- Cancer-related molecular mechanisms research
- Lung Cancer Treatments and Mutations
- Meningioma and schwannoma management
- Viral-associated cancers and disorders
- Speech and Audio Processing
- Cancer-related gene regulation
- Gastric Cancer Management and Outcomes
- Synthesis and biological activity
- Cardiac Valve Diseases and Treatments
- Traditional Chinese Medicine Studies
- Cancer Mechanisms and Therapy
- Hearing Loss and Rehabilitation
- Epigenetics and DNA Methylation
- Acupuncture Treatment Research Studies
- Biochemical effects in animals
- Cancer, Lipids, and Metabolism
- Sensor Technology and Measurement Systems
- Cardiac Imaging and Diagnostics
- Spectroscopy and Chemometric Analyses
First Affiliated Hospital of Zhengzhou University
2024-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2025
Shanxi Medical University
2025
Xi'an Honghui Hospital
2024
Xi'an Jiaotong University
2024
National Taipei University
2020
Taichung Hospital
2018-2019
Taichung Veterans General Hospital
2006
China Medical University
2000-2006
Xiaomi (China)
2002
Background According to GLOBOCAN 2020, lymphoma ranked as the 9 th most common cancer and 12 leading cause of cancer-related deaths worldwide. Traditional diagnostic methods rely on invasive excisional lymph node biopsy, which is an approach with some limitations. Most patients are diagnosed at advanced stage since they asymptomatic beginning, has significantly impacted treatment efficacy prognosis disease. Method This study assessed performance utility a newly developed blood-based assay...
To identify high-risk gastric carcinoma patients with concurrent vascular and neural invasion ("double invasion") who are at heightened risk of progression-free survival (PFS) decline, enabling personalized clinical management. In this multi-center retrospective study, 559 double underwent curative gastrectomy between May 2002 December 2020 were analyzed. Prognostic factors for PFS identified using Lasso-Cox regression. Model validation included internal bootstrapping, calibration plots,...
Recent studies highlight the promise of blood-based multi-cancer early detection (MCED) tests for identifying asymptomatic cancer patients. However, most focus on a single hallmark thus limiting effectiveness due to cancer's heterogeneity. Here, multi-omics test named SeekInCare MCED is reported. incorporates multiple genomic and epigenetic hallmarks, including copy number aberration, fragment size, end motif, oncogenic virus, via shallow whole-genome sequencing from cell-free DNA, alongside...
Purpose . This study aimed to clarify whether it is appropriate choose any measurement location for pulse diagnosis research. Methods A total of 37 subjects were recruited and measured pressure waves at 18 locations (9 per hand “three positions nine indicators”). These data Fourier‐transformed the frequency spectrum, harmonics C0‐C10 each obtained. Box plots generated using SPSS v.22.0 R v.3.4.1. Data compared with multivariate analysis variance (MANOVA) a randomized block design. Results...
Not all patients with angina pectoris have coronary artery stenosis. To facilitate the diagnosis of disease (CAD), we sought to identify predictive factors pulse spectrum analysis, which was developed by Wang and is one technique modern diagnosis. The suffered from chest pain received cardiac catheterization confirm CAD Gensini score were recruited. Their waves radial recorded. Then, performing a fast Fourier transform, 10 amplitude values frequency harmonics obtained. Each harmonic divided...
Pulse diagnosis researches acquiring pulse waves from the wrist radial artery has not yet addressed issue of whether this information is affected by differences in hemodynamic characteristics pressure derived different locations. This study aimed to clarify blood dynamic states are identical with regard "three positions and nine indicators" ((Equation included full-text article.)) listed traditional Chinese medicine (TCM).A total 37 participants CAD group 20 healthy were recruited, measured...
Nutrition is the major source of bioenergy. The present study investigated physiological response to fasting by analyzing effect on pulse spectrum radial artery. Sixteen subjects were allowed take only mineral water for 24 hours, and was measured at intervals during after eating resumed. Data analyzed using one-way analysis variance (ANOVA) with Scheffe's test pairwise comparisons. results indicate second harmonic increased sixth decreased significantly hours fasting. proportions then those...
Traditional Chinese Medicine (TCM) holds that Blood and Qi are fundamental substances in the human body for sustaining normal vital activity. The theory of Qi, Zang-Fu contribute most important theoretical basis physiology TCM. An animal model using conscious rats was employed this study to further comprehend how organisms survive during acute hemorrhage by maintaining functionalities through dynamically regulating visceral physiological conditions. Pulse waves arterial blood pressure before...
Previous work from our laboratory has demonstrated that the percentage differences of 2nd (C2) and 3rd (C3) pulse harmonics related to Kidney Spleen were both increased toward another steady state in rats after acute hemorrhage. Therefore, it is suggested changes spectra might represent ability animals survive a model progressive In this study, difference patterns between survivors non-survivors hemorrhage (by loss 5%, 10% or 20% estimated blood volume) anesthetized determined. Seven rats,...
In order to provide a faster and easier way for outcome prediction of sepsis, this study aimed characterize the pattern arterial pulse spectrum by rat cecum ligation puncture (CLP) model explore whether specific harmonic components are associated with mortality CLP rats, followed comparison accuracy between these variables IL-6. Nineteen Sprague-Dawley rats receiving were analyzed. Femoral artery each was catheterized blood pressure recording sampling in first 24 hours after CLP. The former...
Despite the proven inhibitory effects of drugs targeting vascular endothelial growth factor receptor 2 (VEGFR2) on solid tumors, including non-small cell lung cancer (NSCLC), development anti-NSCLC solely VEGFR2 still faces risks such as off-target and limited efficacy. This study aims to develop a novel fingerprint-enhanced graph attention convolutional network (FnGATGCN) model for predicting activity drugs. Employing multimodal fusion strategy, integrates feature extraction layer that...
Multi-channel audio systems are widely used in modern sound devices for movie theaters and home theaters. However, most files encoded into stereo tracks. When using a multichannel system to play stereophonic audio, the may not produce best possible listening perception. This study aims upmix 5.1-channel sound, thereby enhancing surround experience. The proposed extracts primary center channel ambient side channels. frontal channels reinforced by special equalization technique. Users can use...