A5101826313- Cleft Lip and Palate Research
- Craniofacial Disorders and Treatments
- Orthodontics and Dentofacial Orthopedics
- Dental Health and Care Utilization
- Tracheal and airway disorders
- Dental Radiography and Imaging
- Congenital Anomalies and Fetal Surgery
- dental development and anomalies
- Dental Education, Practice, Research
- Child and Adolescent Health
- Facial Trauma and Fracture Management
- Healthcare Policy and Management
- Temporomandibular Joint Disorders
- Pain Management and Placebo Effect
- Dental Anxiety and Anesthesia Techniques
- Intracranial Aneurysms: Treatment and Complications
- Legume Nitrogen Fixing Symbiosis
- Cerebrovascular and Carotid Artery Diseases
- Body Image and Dysmorphia Studies
- Moyamoya disease diagnosis and treatment
- Hedgehog Signaling Pathway Studies
- Neonatal and Maternal Infections
- Sexuality, Behavior, and Technology
- Plant and fungal interactions
- Psychological Treatments and Assessments
University College London
2006-2025
University of Chieti-Pescara
2024
Great Ormond Street Hospital
2006-2016
Bromley College of Further and Higher Education
2014
Derriford Hospital
2012
University of Cambridge
2006-2007
The King's College
2006
King's College Hospital
2000-2006
Eastman Dental Hospital
2006
De Montfort University
2006
To develop an assessment tool for use in intercenter audit studies of cleft speech and to test its acceptability, validity, reliability. The is be used systematically record report outcomes, providing indication treatment needs continuing burden care.Regional Cleft Center, U.K.The Audit Protocol Speech-Augmented (CAPS-A) was developed by three experts who identified the key features required from existing measures. Criterion validity assessed comparing outcomes reported 20 cases with...
Abstract Objective: To describe facial development and appearance, quality of bone grafts, oral health, patient/parent satisfaction, with clinical outcome, for children in two age cohorts born unilateral cleft lip palate (UCLP) throughout the United Kingdom. Design: Cross-sectional outcome study. Setting: Fifty National Health Service centers. Participants: Children complete UCLP between April 1, 1982, March 31, 1984, (12-year-olds) 1989, 1991 (5-year-olds). Data were collected 239...
Juvenile polyps are present in a number of Mendelian disorders, sometimes association only with gastrointestinal cancer [juvenile polyposis syndrome (JPS)] and as part known syndromes (Cowden, Gorlin Banayan-Zonana) developmental abnormalities, dysmorphic features or extra-intestinal tumours. Recently, gene for JPS was mapped to 18q21.1 the candidate DPC4 (SMAD4) shown carry frameshift mutations some families. We have analysed eight families linkage DPC4. Overall, there no evidence DPC4;...
Abstract Objective: To summarize speech outcomes in children born with unilateral cleft lip and palate (UCLP) throughout the United Kingdom. Design: Prospective descriptive study on a cross-sectional sample of children. Patients/Participants: Data were collected for 238 5-year-olds (born between April 1, 1989, March 31, 1991) 218 12-year-olds 1982, 1984) complete UCLP. Main Outcomes: Ratings intelligibility, nasality, “speech type characteristics” therapy intervention. Conclusions: Nineteen...
This paper reports for the first time presence in anaerobic rumen ciliate Dasytricha ruminantium (Schuberg) of microbody-like organelles, about 0.5 micrometer diameter, with a granular matrix and an equilibrium density approx. 1.18 g/ml. These organelles can be isolated fraction sedimented at 10(5) g-min that contains 67% total pyruvate synthase (EC 1.2.7.1), 66% hydrogenase 1.18.3.1) 20% lactate dehydrogenase 1.1.1.27). Thus several respects this is enzymically similar to those containing...
Abstract Background Pain affects approximately 70% of patients with inflammatory bowel disease (IBD), persisting for five or more years in nearly half, and significantly impacts their quality life.1 However, surveys indicate it is not routinely discussed the IBD clinic.1,2 Clinicians often focus on objective measures activity rather than pain its management, assuming that addressing disease-related factors will alleviate pain.3 Compounding this, find hard to articulate may report because...
Objective To describe facial development and appearance, quality of bone grafts, oral health, patient/parent satisfaction, with clinical outcome, for children in two age cohorts born unilateral cleft lip palate (UCLP) throughout the United Kingdom. Design Cross-sectional outcome study. Setting Fifty National Health Service centers. Participants Children complete UCLP between April 1, 1982, March 31, 1984, (12-year-olds) 1989, 1991 (5-year-olds). Data were collected 239 5-year-olds 218...
Abstract Objective: A critical appraisal of cleft care in the United Kingdom. Design: Retrospective comparative study. Setting: All National Health Service centers Patients/Participants: Children born with unilateral complete clefts lip and palate between April 1, 1982, March 31, 1984 (12-year-olds), 1989, 1991 (5-year-olds). Newly appointed senior clinicians. Main Outcome Measures: Skeletal pattern, dental arch relationship, success alveolar bone grafting, health, facial appearance, oral...
A critical appraisal of cleft care in the United Kingdom.Retrospective comparative study.All National Health Service centers Kingdom.Children born with unilateral complete clefts lip and palate between April 1, 1982, March 31, 1984 (12-year-olds), 1989, 1991 (5-year-olds). Newly appointed senior clinicians.Skeletal pattern, dental arch relationship, success alveolar bone grafting, health, facial appearance, oral health status, patient/parent satisfaction.This paper highlights poor outcomes...
To summarize speech outcomes in children born with unilateral cleft lip and palate (UCLP) throughout the United Kingdom.Prospective descriptive study on a cross-sectional sample of children.Data were collected for 238 5-year-olds (born between April 1, 1989, March 31, 1991) 218 12-year-olds 1982, 1984) complete UCLP.Ratings intelligibility, nasality, "speech type characteristics" therapy intervention.Nineteen percent 4% judged to be impossible understand or just intelligible strangers....
Objectives:To examine the relationships between dental appearance, characteristics of individual and their environment, oral health-related quality life (OHQoL) in young people over time.
The aim of this cross‐sectional clinical outcome study using retrospective data capture treatment histories was to examine the characteristics children born with unilateral cleft lip and palate (UCLP) in United Kingdom (UK) who were not grafted at appropriate age or had an unsuccessful secondary alveolar bone graft.
Abstract Objective: To review the history of cleft care in United Kingdom and rationale methodology a national study. Design: Descriptive overview to introduce this series papers. Setting: Fifty National Health Service teams. Patients/Participants: Two age cohorts, 5-year-olds 12-year-olds, with nonsyndromic complete unilateral lip palate their parents. Main Outcome Measures: Facial development appearance, quality bone grafts, speech, oral health patient/parent satisfaction. Conclusions: The...
Objective To review the history of cleft care in United Kingdom and rationale methodology a national study. Design Descriptive overview to introduce this series papers. Setting Fifty National Health Service teams. Patients/Participants Two age cohorts, 5-year-olds 12-year-olds, with nonsyndromic complete unilateral lip palate their parents. Main Outcome Measures Facial development appearance, quality bone grafts, speech, oral health patient/parent satisfaction. Conclusions The case for...
During the study of two-hundred orthodontic cases under treatment in General Dental Service, four clinicians showed only moderate agreement using British Standard Classification Incisor Malocclusion. Cohen's Kappa statistic was used to measure inter-examiner agreement. The 35 which there high disagreement between examiners were scrutinized determine source this disagreement. Following discussion, revised definitions produced included introduction a Class II-intermediate group. After an...
The angulation of the maxillary central incisor crown to its root has been measured in 191 patients representing four classes malocclusion. Significant differences were only found between Class II Division 1 and 2 groups.
To identify risk factors for poor dental arch relationships in children with unilateral cleft lip and palate the United Kingdom, authors performed a cross-sectional outcome study retrospective data capture of treatment histories under care 44 teams Kingdom. The sample comprised 238 born nonsyndromic complete between April 1, 1989, March 31, 1991, who were 5.0 7.7 years age (mean age, 6.5 years) at time collection. Five-Year-Old Index was used to rank from models. Velopharyngeal insufficiency...
Abstract Objective: Our objective was to evaluate complete unilateral cleft lip and palate repair outcome in the Cleft Unit Perth, Western Australia, by assessment of dentoalveolar relationships. Design: This is a retrospective study. Setting: subjects were individuals under care team Australia. Participants: All patients with available 6-year casts who had been born since January 1, 1985, identified from unit’s database. The nature verified examination birth study models photographs. A...